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Showing 1 to 12 of 77 entries
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Hybridization generates a hopeful monster: a hermaphroditic selfing cichlid.

Royal Society open science

Svensson O, Smith A, García-Alonso J, van Oosterhout C.
PMID: 27069660
R Soc Open Sci. 2016 Mar 23;3(3):150684. doi: 10.1098/rsos.150684. eCollection 2016 Mar.

Compared with other phylogenetic groups, self-fertilization (selfing) is exceedingly rare in vertebrates and is known to occur only in one small clade of fishes. Here we report observing one F1-hybrid individual that developed into a functional hermaphrodite after crossing...

Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study.

BMJ open

Lo Tam Loi AT, Hoonhorst SJ, Franciosi L, Bischoff R, Hoffmann RF, Heijink I, van Oosterhout AJ, Boezen HM, Timens W, Postma DS, Lammers JW, Koenderman L, Ten Hacken NH.
PMID: 23377993
BMJ Open. 2013 Feb 01;3(2). doi: 10.1136/bmjopen-2012-002178. Print 2013.

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with pulmonary and extra-pulmonary manifestations. Although COPD is a complex disease, diagnosis and staging are still based on simple spirometry measurements. Different COPD phenotypes exist based on clinical, physiological,...

Fine mapping the .

NPJ aging and mechanisms of disease

van Leeuwen EM, Huffman JE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Feitosa MF, Duan Q, Schraut KE, Navarro P, van Vliet-Ostaptchouk JV, Zhu G, Mbarek H, Trompet S, Verweij N, Lyytikäinen LP, Deelen J, Nolte IM, van der Laan SW, Davies G, Vermeij-Verdoold AJ, van Oosterhout AA, Vergeer-Drop JM, Arking DE, Trochet H, Medina-Gomez C, Rivadeneira F, Uitterlinden AG, Dehghan A, Franco OH, Sijbrands EJ, Hofman A, White CC, Mychaleckyj JC, Peloso GM, Swertz MA, Willemsen G, de Geus EJ, Milaneschi Y, Penninx BW, Ford I, Buckley BM, de Craen AJ, Starr JM, Deary IJ, Pasterkamp G, Oldehinkel AJ, Snieder H, Slagboom PE, Nikus K, Kähönen M, Lehtimäki T, Viikari JS, Raitakari OT, van der Harst P, Jukema JW, Hottenga JJ, Boomsma DI, Whitfield JB, Montgomery G, Martin NG, Polasek O, Vitart V, Hayward C, Kolcic I, Wright AF, Rudan I, Joshi PK, Wilson JF, Lange LA, Wilson JG, Gudnason V, Harris TB, Morrison AC, Borecki IB, Rich SS, Padmanabhan S, Psaty BM, Rotter JI, Smith BH, Boerwinkle E, Cupples LA, van Duijn C.
PMID: 28721259
NPJ Aging Mech Dis. 2015 Nov 12;1:15011. doi: 10.1038/npjamd.2015.11. eCollection 2015.

BACKGROUND: Individuals with exceptional longevity and their offspring have significantly larger high-density lipoprotein concentrations (HDL-C) particle sizes due to the increased homozygosity for the I405V variant in the cholesteryl ester transfer protein (METHODS: We performed a meta-analysis of HDL-C...

Letter to the Editor: Should we focus on quality or quantity in meta-analyses?.

Psychological medicine

van Oosterhout B, Smit F, Krabbendam L, Castelein S, Staring AB, van der Gaag M.
PMID: 26888290
Psychol Med. 2016 Jul;46(9):2003-5. doi: 10.1017/S003329171600009X. Epub 2016 Feb 18.

No abstract available.

The role of histopathologic subtyping in predicting neurologic complications in small-cell lung-cancer.

International journal of oncology

Vanoosterhout A, Thunnissen F, Volovics A, Vandenpol M, Tenvelde G, Twijnstra A.
PMID: 21566913
Int J Oncol. 1994 Jan;4(1):201-5. doi: 10.3892/ijo.4.1.201.

We examined the significance of histologic subtyping of small cell lung cancer (SCLC) as a prognostic factor for neurologic complications and in particular central nervous system (CNS) metastases. Pretreatment material of 239 consecutive patients with SCLC was retrospectively reexamined...

Application of evidence-informed deliberative processes in health technology assessment in low- and middle-income countries.

International journal of technology assessment in health care

Oortwijn W, van Oosterhout S, Kapiriri L.
PMID: 32715993
Int J Technol Assess Health Care. 2020 Jul 27;1-5. doi: 10.1017/S0266462320000549. Epub 2020 Jul 27.

OBJECTIVES: Evidence-informed deliberative processes (EDPs) were introduced to guide health technology assessment (HTA) agencies to improve their processes toward more legitimate decision making. A survey among members of the International Network of Agencies for HTA (INAHTA) showed that EDPs...

Lessons learned from early closure of a clinical trial for steroid-refractory acute GVHD.

Bone marrow transplantation

Meyers G, Hamadani M, Martens M, Ali H, Choe H, Dawson P, Harris AC, van Hooren E, Klaassen W, Leifer E, MacMillan ML, van Oosterhout Y, Perez L, Pusic I, Vo P, Levine JE.
PMID: 34815518
Bone Marrow Transplant. 2021 Nov 23; doi: 10.1038/s41409-021-01529-x. Epub 2021 Nov 23.

No abstract available.

Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.

Journal of medicinal chemistry

Wellaway CR, Baldwin IR, Bamborough P, Barker D, Bartholomew MA, Chung CW, Dümpelfeld B, Evans JP, Fazakerley NJ, Homes P, Keeling SP, Lewell XQ, McNab FW, Morley J, Needham D, Neu M, van Oosterhout AJM, Pal A, Reinhard FBM, Rianjongdee F, Robertson CM, Rowland P, Shah RR, Sherriff EB, Sloan LA, Teague S, Thomas DA, Wellaway N, Wojno-Picon J, Woolven JM, Coe DM.
PMID: 34928601
J Med Chem. 2021 Dec 20; doi: 10.1021/acs.jmedchem.1c01765. Epub 2021 Dec 20.

The Janus family of tyrosine kinases (JAK1, JAK2, JAK3, and TYK2) play an essential role in the receptor signaling of cytokines that have been implicated in the pathogenesis of severe asthma, and there is emerging interest in the development...

Fungal Burden and Raised Intracranial Pressure Are Independently Associated With Visual Loss in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis.

Open forum infectious diseases

Molloy SF, Ross B, Kanyama C, Mfinanga S, Lesikari S, Heyderman RS, Kalata N, Ellis J, Kouanfack C, Chanda D, Temfack E, Lakhi S, Moodley A, Chan AK, van Oosterhout JJ, Mapoure Y, Mwaba P, Lalloo DG, Wang D, Lortholary O, Jaffar S, Hosseinipour MC, Loyse A, Harrison TS, Bicanic T.
PMID: 33937434
Open Forum Infect Dis. 2021 Feb 05;8(4):ofab066. doi: 10.1093/ofid/ofab066. eCollection 2021 Apr.

Among 472 patients with human immunodeficiency virus-associated cryptococcal meningitis, 16% had severe visual loss at presentation, and 46% of these were 4-week survivors and remained severely impaired. Baseline cerebrospinal fluid opening pressure ≥40 cmH

Sex-specific differences and how to handle them in early psoriatic arthritis.

Arthritis research & therapy

Passia E, Vis M, Coates LC, Soni A, Tchetverikov I, Gerards AH, Kok MR, Vos PAJM, Korswagen L, Fodili F, Goekoop-Ruiterman YPM, van der Kaap J, van Oosterhout M, Luime JJ.
PMID: 35016726
Arthritis Res Ther. 2022 Jan 11;24(1):22. doi: 10.1186/s13075-021-02680-y.

OBJECTIVES: The prevalence of psoriatic arthritis (PsA) is the same in men and women; however, the latter experience a higher burden of disease and are affected more frequently by polyarthritis. Here, we performed an early PsA cohort analysis to...

The effect of needle size on cerebrospinal fluid collection time and post-dural puncture headache: A retrospective cohort study.

Headache

van Dongen RM, Onderwater GLJ, Pelzer N, Zielman R, van Oosterhout WPJ, van Zwet EW, Ferrari MD, Terwindt GM.
PMID: 33452678
Headache. 2021 Feb;61(2):329-334. doi: 10.1111/head.14046. Epub 2021 Jan 16.

OBJECTIVE: The main objective of this study was to compare cerebrospinal fluid (CSF) collection time and patient's discomfort between 20G (a)traumatic and 22G atraumatic needles.BACKGROUND: Risk of post-dural puncture headache (PDPH) is decreased using atraumatic needles. Smaller needles may...

Short-term Mortality Outcomes of HIV-Associated Cryptococcal Meningitis in Antiretroviral Therapy-Naïve and -Experienced Patients in Sub-Saharan Africa.

Open forum infectious diseases

Kalata N, Ellis J, Kanyama C, Kuoanfank C, Temfack E, Mfinanga S, Lesikari S, Chanda D, Lakhi S, Nyazika T, Chan AK, van Oosterhout JJ, Chen T, Hosseinipour MC, Lortholary O, Wang D, Jaffar S, Loyse A, Heyderman RS, Harrison TS, Molloy SF.
PMID: 34646905
Open Forum Infect Dis. 2021 Jul 28;8(10):ofab397. doi: 10.1093/ofid/ofab397. eCollection 2021 Oct.

BACKGROUND: An increasing proportion of patients with HIV-associated cryptococcal meningitis have received antiretroviral therapy (ART) before presentation. There is some evidence suggesting an increased 2-week mortality in those receiving ART for 14 days. However, presentation and outcomes for cryptococcal...

Showing 1 to 12 of 77 entries