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Showing 1 to 8 of 8 entries
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Insulin-like growth factor II-mediated proliferation of human neuroblastoma.

The Journal of clinical investigation

El-Badry OM, Helman LJ, Chatten J, Steinberg SM, Evans AE, Israel MA.
PMID: 1991849
J Clin Invest. 1991 Feb;87(2):648-57. doi: 10.1172/JCI115042.
Free PMC Article

Neuroblastoma is an embryonal tumor that typically arises in cells of the developing adrenal medulla. IGF-II mRNA is expressed at high levels in the adrenal cortex before birth but it is not detectable until after birth in the adrenal...

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El-Badry OM, Helman LJ, Chatten J, et al. Insulin-like growth factor II-mediated proliferation of human neuroblastoma. J Clin Invest. 1991;87(2):648-57doi: 10.1172/JCI115042.
El-Badry, O. M., Helman, L. J., Chatten, J., Steinberg, S. M., Evans, A. E., & Israel, M. A. (1991). Insulin-like growth factor II-mediated proliferation of human neuroblastoma. The Journal of clinical investigation, 87(2), 648-57. https://doi.org/10.1172/JCI115042
El-Badry, O M, et al. "Insulin-like growth factor II-mediated proliferation of human neuroblastoma." The Journal of clinical investigation vol. 87,2 (1991): 648-57. doi: https://doi.org/10.1172/JCI115042
El-Badry OM, Helman LJ, Chatten J, Steinberg SM, Evans AE, Israel MA. Insulin-like growth factor II-mediated proliferation of human neuroblastoma. J Clin Invest. 1991 Feb;87(2):648-57. doi: 10.1172/JCI115042. PMID: 1991849; PMCID: PMC296355.
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Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II.

The Journal of clinical investigation

El-Badry OM, Romanus JA, Helman LJ, Cooper MJ, Rechler MM, Israel MA.
PMID: 2547840
J Clin Invest. 1989 Sep;84(3):829-39. doi: 10.1172/JCI114243.
Free PMC Article

Insulin-like growth factor II (IGF-II) mRNA was increased in two of eight neuroblastomas and in eight of eight pheochromocytomas, tumors of the adrenal medulla that occur in childhood and adulthood, respectively. RNA encoding the type I IGF receptor, the...

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El-Badry OM, Romanus JA, Helman LJ, et al. Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. J Clin Invest. 1989;84(3):829-39doi: 10.1172/JCI114243.
El-Badry, O. M., Romanus, J. A., Helman, L. J., Cooper, M. J., Rechler, M. M., & Israel, M. A. (1989). Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. The Journal of clinical investigation, 84(3), 829-39. https://doi.org/10.1172/JCI114243
El-Badry, O M, et al. "Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II." The Journal of clinical investigation vol. 84,3 (1989): 829-39. doi: https://doi.org/10.1172/JCI114243
El-Badry OM, Romanus JA, Helman LJ, Cooper MJ, Rechler MM, Israel MA. Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. J Clin Invest. 1989 Sep;84(3):829-39. doi: 10.1172/JCI114243. PMID: 2547840; PMCID: PMC329726.
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Insulin-like growth factor II gene expression in human neuroblastoma.

Progress in clinical and biological research

el-Badry OM.
PMID: 2068141
Prog Clin Biol Res. 1991;366:249-56.

No abstract available.

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el-Badry OM. Insulin-like growth factor II gene expression in human neuroblastoma. Prog Clin Biol Res. 1991;366:249-56
el-Badry, O. M. (1991). Insulin-like growth factor II gene expression in human neuroblastoma. Progress in clinical and biological research, 366249-56.
el-Badry, O M. "Insulin-like growth factor II gene expression in human neuroblastoma." Progress in clinical and biological research vol. 366 (1991): 249-56.
el-Badry OM. Insulin-like growth factor II gene expression in human neuroblastoma. Prog Clin Biol Res. 1991;366:249-56. PMID: 2068141.
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Design and synthesis of novel imidazo[4,5-b]pyridine based compounds as potent anticancer agents with CDK9 inhibitory activity.

Bioorganic chemistry

Ghanem NM, Farouk F, George RF, Abbas SES, El-Badry OM.
PMID: 30025343
Bioorg Chem. 2018 Oct;80:565-576. doi: 10.1016/j.bioorg.2018.07.006. Epub 2018 Jul 06.

New imidazo[4,5-b]pyridine derivatives were designed, synthesized and screened for their anticancer activity against breast (MCF-7) and colon (HCT116) cancer cell lines. Nine compounds (I, II, IIIa, IIIb, IV, VI, VIIa, VIII, IX) showed significant activity against MCF-7, while six...

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Ghanem NM, Farouk F, George RF, et al. Design and synthesis of novel imidazo[4,5-b]pyridine based compounds as potent anticancer agents with CDK9 inhibitory activity. Bioorg Chem. 2018;80:565-576doi: 10.1016/j.bioorg.2018.07.006.
Ghanem, N. M., Farouk, F., George, R. F., Abbas, S. E. S., & El-Badry, O. M. (2018). Design and synthesis of novel imidazo[4,5-b]pyridine based compounds as potent anticancer agents with CDK9 inhibitory activity. Bioorganic chemistry, 80565-576. https://doi.org/10.1016/j.bioorg.2018.07.006
Ghanem, Nada M, et al. "Design and synthesis of novel imidazo[4,5-b]pyridine based compounds as potent anticancer agents with CDK9 inhibitory activity." Bioorganic chemistry vol. 80 (2018): 565-576. doi: https://doi.org/10.1016/j.bioorg.2018.07.006
Ghanem NM, Farouk F, George RF, Abbas SES, El-Badry OM. Design and synthesis of novel imidazo[4,5-b]pyridine based compounds as potent anticancer agents with CDK9 inhibitory activity. Bioorg Chem. 2018 Oct;80:565-576. doi: 10.1016/j.bioorg.2018.07.006. Epub 2018 Jul 06. PMID: 30025343.
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Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research

El-Badry OM, Minniti C, Kohn EC, Houghton PJ, Daughaday WH, Helman LJ.
PMID: 2177632
Cell Growth Differ. 1990 Jul;1(7):325-31.
Free Article

Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood and appears to arise from developing striated muscle-forming cells. Since insulin-like growth factor II (IGF-II) is involved in normal muscle growth and maturation and elevated IGF-II mRNA levels have...

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El-Badry OM, Minniti C, Kohn EC, et al. Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth Differ. 1990;1(7):325-31
El-Badry, O. M., Minniti, C., Kohn, E. C., Houghton, P. J., Daughaday, W. H., & Helman, L. J. (1990). Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1(7), 325-31.
El-Badry, O M, et al. "Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors." Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research vol. 1,7 (1990): 325-31.
El-Badry OM, Minniti C, Kohn EC, Houghton PJ, Daughaday WH, Helman LJ. Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth Differ. 1990 Jul;1(7):325-31. PMID: 2177632.
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Design & synthesis of novel oxazolone & triazinone derivatives and their biological evaluation as COX-2 inhibitors.

Bioorganic chemistry

Mohamed LW, El-Badry OM, El-Ansary AK, Ismael A.
PMID: 28500957
Bioorg Chem. 2017 Jun;72:308-314. doi: 10.1016/j.bioorg.2017.04.012. Epub 2017 Apr 24.

A new series of oxazolones and triazinones were designed and synthesized and evaluated against both COX-1 and COX-2 enzymes. Full structure elucidation of the new derivatives was performed using microanalyses, IR, 1H NMR, 13C NMR and mass spectra. Most...

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Mohamed LW, El-Badry OM, El-Ansary AK, et al. Design & synthesis of novel oxazolone & triazinone derivatives and their biological evaluation as COX-2 inhibitors. Bioorg Chem. 2017;72:308-314doi: 10.1016/j.bioorg.2017.04.012.
Mohamed, L. W., El-Badry, O. M., El-Ansary, A. K., & Ismael, A. (2017). Design & synthesis of novel oxazolone & triazinone derivatives and their biological evaluation as COX-2 inhibitors. Bioorganic chemistry, 72308-314. https://doi.org/10.1016/j.bioorg.2017.04.012
Mohamed, Lamia W, et al. "Design & synthesis of novel oxazolone & triazinone derivatives and their biological evaluation as COX-2 inhibitors." Bioorganic chemistry vol. 72 (2017): 308-314. doi: https://doi.org/10.1016/j.bioorg.2017.04.012
Mohamed LW, El-Badry OM, El-Ansary AK, Ismael A. Design & synthesis of novel oxazolone & triazinone derivatives and their biological evaluation as COX-2 inhibitors. Bioorg Chem. 2017 Jun;72:308-314. doi: 10.1016/j.bioorg.2017.04.012. Epub 2017 Apr 24. PMID: 28500957.
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Growth regulation of human neuroblastoma.

Cancer treatment and research

el-Badry OM, Israel MA.
PMID: 1363353
Cancer Treat Res. 1992;63:105-28. doi: 10.1007/978-1-4615-3088-6_5.

No abstract available.

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el-Badry OM, Israel MA. Growth regulation of human neuroblastoma. Cancer Treat Res. 1992;63:105-28doi: 10.1007/978-1-4615-3088-6_5.
el-Badry, O. M., & Israel, M. A. (1992). Growth regulation of human neuroblastoma. Cancer treatment and research, 63105-28. https://doi.org/10.1007/978-1-4615-3088-6_5
el-Badry, O M, and Israel, M A. "Growth regulation of human neuroblastoma." Cancer treatment and research vol. 63 (1992): 105-28. doi: https://doi.org/10.1007/978-1-4615-3088-6_5
el-Badry OM, Israel MA. Growth regulation of human neuroblastoma. Cancer Treat Res. 1992;63:105-28. doi: 10.1007/978-1-4615-3088-6_5. PMID: 1363353.
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Medium conditioned by human neuroblastoma BE(2)-C cells contains an autocrine/paracrine acting growth factor with properties similar to insulin-like growth factor II.

Progress in clinical and biological research

el-Badry OM, Meyers MB, Spengler BA, Chang TD, Ross RA, Biedler JL.
PMID: 2068142
Prog Clin Biol Res. 1991;366:257-66.

No abstract available.

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el-Badry OM, Meyers MB, Spengler BA, et al. Medium conditioned by human neuroblastoma BE(2)-C cells contains an autocrine/paracrine acting growth factor with properties similar to insulin-like growth factor II. Prog Clin Biol Res. 1991;366:257-66
el-Badry, O. M., Meyers, M. B., Spengler, B. A., Chang, T. D., Ross, R. A., & Biedler, J. L. (1991). Medium conditioned by human neuroblastoma BE(2)-C cells contains an autocrine/paracrine acting growth factor with properties similar to insulin-like growth factor II. Progress in clinical and biological research, 366257-66.
el-Badry, O M, et al. "Medium conditioned by human neuroblastoma BE(2)-C cells contains an autocrine/paracrine acting growth factor with properties similar to insulin-like growth factor II." Progress in clinical and biological research vol. 366 (1991): 257-66.
el-Badry OM, Meyers MB, Spengler BA, Chang TD, Ross RA, Biedler JL. Medium conditioned by human neuroblastoma BE(2)-C cells contains an autocrine/paracrine acting growth factor with properties similar to insulin-like growth factor II. Prog Clin Biol Res. 1991;366:257-66. PMID: 2068142.
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Showing 1 to 8 of 8 entries