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Showing 1 to 12 of 16 entries
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Genetic Influences on Dentognathic Morphology in the Jirel population of Nepal.

Anatomical record (Hoboken, N.J. : 2007)

Hardin AM, Knigge RP, Duren DL, Williams-Blangero S, Subedi J, Mahaney MC, Sherwood RJ.
PMID: 34981668
Anat Rec (Hoboken). 2022 Jan 03; doi: 10.1002/ar.24857. Epub 2022 Jan 03.

Patterns of genetic variation and covariation impact the evolution of the craniofacial complex and contribute to clinically significant malocclusions in modern human populations. Previous quantitative genetic studies have estimated the heritabilities and genetic correlations of skeletal and dental traits...

Genetic differentiation between baboon subspecies: Relevance for biomedical research.

American journal of primatology

Williams-Blangero S, Vandeberg JL, Blangero J, Konigsberg L, Dyke B.
PMID: 31963994
Am J Primatol. 1990;20(2):67-81. doi: 10.1002/ajp.1350200202.

The use of common names which may encompass a number of subspecies or species is pervasive in the biomedical literature. Failure to identify the complete taxonomic classification of research subjects presents a source of error for scientists attempting to...

Heritability of age at first birth in captive olive baboons.

American journal of primatology

Williams-Blangero S, Blangero J.
PMID: 31936949
Am J Primatol. 1995;37(3):233-239. doi: 10.1002/ajp.1350370305.

The evolution of life history traits is a topic of growing interest in primatology. Traits associated with fertility, such as age at menarche and age at first birth, have great significance for natural selection, and knowing the genetic basis...

Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in .

Circulation. Genomic and precision medicine

Blackburn NB, Meikle PJ, Peralta JM, Kumar S, Leandro AC, Bellinger MA, Giles C, Huynh K, Mahaney MC, Göring HHH, VandeBerg JL, Williams-Blangero S, Glahn DC, Duggirala R, Blangero J, Michael LF, Curran JE.
PMID: 33887960
Circ Genom Precis Med. 2021 Jun;14(3):e003232. doi: 10.1161/CIRCGEN.120.003232. Epub 2021 Apr 22.

BACKGROUND: The identification and understanding of therapeutic targets for atherosclerotic cardiovascular disease is of fundamental importance given its global health and economic burden. Inhibition of ANGPTL3 (angiopoietin-like 3) has demonstrated a cardioprotective effect, showing promise for atherosclerotic cardiovascular disease...

Efficient Generation of Functional Hepatocytes from Human Induced Pluripotent Stem Cells for Disease Modeling and Disease Gene Discovery.

Methods in molecular biology (Clifton, N.J.)

Kumar S, Curran JE, Williams-Blangero S, Blangero J.
PMID: 33772461
Methods Mol Biol. 2021 Mar 27; doi: 10.1007/7651_2021_375. Epub 2021 Mar 27.

In vitro hepatocyte cell models are being used to study the pathogenesis of liver disease and in the discovery and preclinical stages of drug development. The culture of hepatic cell lines and primary hepatocytes as in vitro cell models...

Genetic analysis of chest dimensions in a high altitude Tibetan population from upper Chumik, Nepal.

American journal of human biology : the official journal of the Human Biology Council

Williams-Blangero S, Blangero J, Beall CM.
PMID: 28548361
Am J Hum Biol. 1993;5(6):719-724. doi: 10.1002/ajhb.1310050615.

Studies of high altitude Andean natives generally report large chest dimensions relative to sea level groups, while results from studies of Himalayan populations are not consistent. One hypothesis is that this may represent different adaptive patterns in the two...

Future Costs of Chimpanzees in U.S. Research Institutions.

ILAR journal

Dyke B, Williams-Blangero S, Mamelka PM, Goodwin WJ.
PMID: 11528040
ILAR J. 1995;37(4):193-198. doi: 10.1093/ilar.37.4.193.

No abstract available.

Genetic relationships among three squirrel monkey types: Implications for taxonomy, biomedical research, and captive breeding.

American journal of primatology

Vandeberg JL, Williams-Blangero S, Moore CM, Cheng ML, Abee CR.
PMID: 31963960
Am J Primatol. 1990;22(2):101-111. doi: 10.1002/ajp.1350220204.

Fourteen electrophoretically variable and 12 monomorphic erythrocytic and serum proteins were used to determine the genetic relationships among Bolivian squirrel monkeys (Saimiri boliviensis boliviensis), Peruvian squirrel monkeys (Saimiri boliviensis peruviensis), and Guyanese squirrel monkeys (Saimiri sciureus sciureus). The results...

UniMóvil: A Mobile Health Clinic Providing Primary Care to the Colonias of the Rio Grande Valley, South Texas.

Frontiers in public health

Manusov EG, Diego VP, Smith J, Garza JR, Lowdermilk J, Blangero J, Williams-Blangero S, Fernandez F.
PMID: 31497586
Front Public Health. 2019 Aug 21;7:215. doi: 10.3389/fpubh.2019.00215. eCollection 2019.

No abstract available.

Assessing the effects of candidate genes on quantitative traits in primate populations.

American journal of primatology

Blangero J, Williams-Blangero S, Hixson JE.
PMID: 31948141
Am J Primatol. 1992;27(2):119-132. doi: 10.1002/ajp.1350270207.

Recent progress in molecular and biochemical genetics has led to the identification of numerous polymorphic candidate genes likely to be important in the determination of quantitative variation in physiological processes. In this paper, we review a statistical framework ("measured...

The genetic demography of a chimpanzee colony.

American journal of primatology

Williams-Blangero S, Eichberg JW, Dyke B.
PMID: 31948140
Am J Primatol. 1992;27(2):73-83. doi: 10.1002/ajp.1350270203.

Chimpanzees used for biomedical research must be bred in captivity because of restrictions on importation. Because they are large and expensive animals, population sizes at breeding facilities are limited. This implies that inbreeding at some level is inevitable and...

Bioethics, Animal Research, and Ethical Theory.

ILAR journal

Russow LM, Donnelley S, Dresser R, VandeBerg JL, Williams-Blangero S, Wolfle TL.
PMID: 11533512
ILAR J. 1999;40(1):15-21. doi: 10.1093/ilar.40.1.15.

No abstract available.

Showing 1 to 12 of 16 entries