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Showing 1 to 12 of 23 entries
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Introduction of the Carotenoid Biosynthesis α-Branch Into .

Frontiers in plant science

Lehmann M, Vamvaka E, Torrado A, Jahns P, Dann M, Rosenhammer L, Aziba A, Leister D, Rühle T.
PMID: 34295345
Front Plant Sci. 2021 Jul 06;12:699424. doi: 10.3389/fpls.2021.699424. eCollection 2021.

Lutein, made by the α-branch of the methyl-erythritol phosphate (MEP) pathway, is one of the most abundant xanthophylls in plants. It is involved in the structural stabilization of light-harvesting complexes, transfer of excitation energy to chlorophylls and photoprotection. In...

Applications of Therapeutic Apheresis in Patients with Malignant Disease.

The oncologist

Pineda AA, Vamvakas EC.
PMID: 10388036
Oncologist. 1997;2(2):94-103.

Therapeutic apheresis (TA) provides the means for the removal of blood components that are abnormal or that circulate in excessive amounts and have a defined pathogenetic role, or are thought to have one. Multiple disease processes have been treated...

Tubular Carcinoma of the Breast: Immunohistochemical and DNA Flow Cytometric Profile.

The breast journal

Fasano M, Vamvakas E, Delgado Y, Inghirami G, Mitnick J, Roses D, Feiner H.
PMID: 11348296
Breast J. 1999 Jul;5(4):252-255. doi: 10.1046/j.1524-4741.1999.98103.x.

Molecular markers of ordinary invasive ductal carcinoma of the breast have been extensively studied and their prognostic significance has been assessed. A common variant of breast cancer, tubular carcinoma, has an excellent prognosis as judged from several clinicopathologic studies....

INTERSTAARS: Attention training for infants with elevated likelihood of developing ADHD: A proof-of-concept randomised controlled trial.

Translational psychiatry

Goodwin A, Jones EJH, Salomone S, Mason L, Holman R, Begum-Ali J, Hunt A, Ruddock M, Vamvakas G, Robinson E, Holden CJ, Taylor C, Smith TJ, Sonuga-Barke E, Bolton P, Charman T, Pickles A, Wass S, Johnson MH.
PMID: 34930893
Transl Psychiatry. 2021 Dec 20;11(1):644. doi: 10.1038/s41398-021-01698-9.

Attention-deficit/hyperactivity disorder (ADHD) is first diagnosed during middle childhood, when patterns of difficulty are often established. Pre-emptive approaches that strengthen developing cognitive systems could offer an alternative to post-diagnostic interventions. This proof-of-concept randomised controlled trial (RCT) tested whether computerised...

The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease.

Journal of Parkinson's disease

Stephenson D, Hill D, Cedarbaum JM, Tome M, Vamvakas S, Romero K, Conrado DJ, Dexter DT, Seibyl J, Jennings D, Nicholas T, Matthews D, Xie Z, Imam S, Maguire P, Russell D, Gordon MF, Stebbins GT, Somer E, Gallagher J, Roach A, Basseches P, Grosset D, Marek K.
PMID: 31524182
J Parkinsons Dis. 2019;9(4):825. doi: 10.3233/JPD-199003.

No abstract available.

Cancer in end-stage renal disease: potential factors involved -editorial-.

American journal of nephrology

Vamvakas S, Bahner U, Heidland A.
PMID: 9569948
Am J Nephrol. 1998;18(2):89-95. doi: 10.1159/000013314.

Increased incidence of cancer at various sites is observed in patients with end-stage renal disease (ESRD). In particular, lymphomas and carcinomas of the kidney, prostate, liver and uterus show an enhanced prevalence in these subjects compared with the general...

Two-stage sampling in the estimation of growth parameters and percentile norms: sample weights versus auxiliary variable estimation.

BMC medical research methodology

Vamvakas G, Norbury C, Pickles A.
PMID: 34404347
BMC Med Res Methodol. 2021 Aug 17;21(1):173. doi: 10.1186/s12874-021-01353-3.

BACKGROUND: The use of auxiliary variables with maximum likelihood parameter estimation for surveys that miss data by design is not a widespread approach, despite its documented improved efficiency over traditional approaches that deploy sampling weights. Although efficiency gains from...

INTERSTAARS: Attention training for infants with elevated likelihood of developing ADHD: A proof-of-concept randomised controlled trial.

Translational psychiatry

Goodwin A, Jones EJH, Salomone S, Mason L, Holman R, Begum-Ali J, Hunt A, Ruddock M, Vamvakas G, Robinson E, Holden CJ, Taylor C, Smith TJ, Sonuga-Barke E, Bolton P, Charman T, Pickles A, Wass S, Johnson MH.
PMID: 34930893
Transl Psychiatry. 2021 Dec 20;11(1):644. doi: 10.1038/s41398-021-01698-9.

Attention-deficit/hyperactivity disorder (ADHD) is first diagnosed during middle childhood, when patterns of difficulty are often established. Pre-emptive approaches that strengthen developing cognitive systems could offer an alternative to post-diagnostic interventions. This proof-of-concept randomised controlled trial (RCT) tested whether computerised...

Toward a patient-based paradigm for blood transfusion.

Journal of blood medicine

Farrugia A, Vamvakas E.
PMID: 24520208
J Blood Med. 2014 Jan 31;5:5-13. doi: 10.2147/JBM.S55769. eCollection 2014.

The current "manufacturing paradigm" of transfusion practice has detached transfusion from the clinical environment. As an example, fresh whole blood in large-volume hemorrhage may be superior to whole blood reconstituted from multiple components. Multicomponent apheresis can overcome logistical difficulties...

Advanced Therapy Medicinal Products for Rare Diseases: State of Play of Incentives Supporting Development in Europe.

Frontiers in medicine

Farkas AM, Mariz S, Stoyanova-Beninska V, Celis P, Vamvakas S, Larsson K, Sepodes B.
PMID: 28560211
Front Med (Lausanne). 2017 May 16;4:53. doi: 10.3389/fmed.2017.00053. eCollection 2017.

In 2008, the European Union introduced the Advanced Medicines Regulation aiming to improve regulation of advanced therapy medicinal products (ATMPs). We applied the ATMPs classification definitions in this Regulation to understand the link of this emerging group of medicinal...

Cancer cachexia syndrome and clinical outcome in patients with metastatic non-small cell lung cancer treated with PD-1/PD-L1 inhibitors: results from a prospective, observational study.

Translational lung cancer research

Rounis K, Makrakis D, Tsigkas AP, Georgiou A, Galanakis N, Papadaki C, Monastirioti A, Vamvakas L, Kalbakis K, Vardakis N, Kontogianni M, Gioulbasanis I, Mavroudis D, Agelaki S.
PMID: 34584855
Transl Lung Cancer Res. 2021 Aug;10(8):3538-3549. doi: 10.21037/tlcr-21-460.

BACKGROUND: Cancer cachexia syndrome (CCS) is an adverse prognostic factor in cancer patients undergoing chemotherapy or surgical procedures. We performed a prospective study to investigate the effect of CCS on treatment outcomes in patients with non-oncogene driven metastatic non-small...

Genotoxicity of haloalkene and haloalkane glutathione S-conjugates in porcine kidney cells.

Toxicology in vitro : an international journal published in association with BIBRA

Vamvakas S, Dekant W, Henschler D.
PMID: 20702313
Toxicol In Vitro. 1989;3(2):151-6. doi: 10.1016/0887-2333(89)90058-1.

The genotoxicity of the glutathione S-conjugates S-(12-dichlorovinyl)glutathione (DCVG), S-(1,2,2-trichlorovinyl)glutathione (TCVG), S-(1,2,3,4,4-pentachlorobutadienyl)glutathione (PCBG) and S-(2-chloroethyl)glutathione (CEG) was investigated in LLC-PK1, a cultured line of porcine kidney cells that exhibits many properties of proximal tubular cells. DNA damage caused by treatment...

Showing 1 to 12 of 23 entries