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Diverse application platform for hard X-ray diffraction in SACLA (DAPHNIS): application to serial protein crystallography using an X-ray free-electron laser

pipeline programs

Nango E, Song C, Sugahara M.
GSID: LSRZiSt4RNwJ
K Tono, E Nango, M Sugahara, C Song… - Journal of synchrotron …, 2015 - scripts.iucr.org

An experimental system for serial femtosecond crystallography using an X-ray free-electron laser (XFEL) has been developed. It basically consists of a sample chamber, fluid injectors …

[Observation on utilization of health records for expectant mothers].

Josanpu zasshi = The Japanese journal for midwife

Ishizuka I, Sugahara T, Nagao M, Nakayama C, Nakazato S.
PMID: 4495764
Josanpu Zasshi. 1974 Mar;28(3):147-54.

No abstract available.

Efficient Organocatalytic Construction of C4-Alkyl Substituted Piperidines and Their Application to the Synthesis of (+)-α-Skytanthine.

Chemistry (Weinheim an der Bergstrasse, Germany)

Shiomi S, Sugahara E, Ishikawa H.
PMID: 26333476
Chemistry. 2015 Oct 12;21(42):14758-63. doi: 10.1002/chem.201503117. Epub 2015 Sep 03.

Chiral piperidines which contain an alkyl group at C4 positions are one of the important architectures because it is appeared in several natural products. An efficient protocol for the preparation of C4-alkyl substituted chiral piperidines using secondary amine catalyzed...

Rapid and early α-fetoprotein and des-γ-carboxy prothrombin responses to initial arterial infusion chemotherapy predict treatment outcomes of advanced hepatocellular carcinoma.

Molecular and clinical oncology

Oyama K, Koda M, Sugihara T, Kishina M, Miyoshi K, Okamoto T, Hodotsuka M, Fujise Y, Matono T, Tokunaga S, Okamoto K, Hosho K, Okano J, Murawaki Y.
PMID: 26137283
Mol Clin Oncol. 2015 May;3(3):655-662. doi: 10.3892/mco.2015.523. Epub 2015 Mar 03.

The aim of the present study was to predict the effects of transarterial infusion (TAI) chemotherapy based on early changes in α-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP) in patients with advanced hepatocellular carcinoma (HCC). Seventy-four patients who underwent TAI...

A study of the effect of visual depth information on upper limb movement by use of measurement of smoothness.

Journal of physical therapy science

Kato N, Tanaka T, Sugihara S, Shimizu K, Kudo N.
PMID: 27190441
J Phys Ther Sci. 2016 Apr;28(4):1134-41. doi: 10.1589/jpts.28.1134. Epub 2016 Apr 28.

[Purpose] This study verified that the smoothness of reaching movements is able to quantitatively evaluate the effects of two- and three-dimensional images on movement in healthy people. In addition, clinical data of cerebrovascular accident patients were also analyzed by...

Enantioselective incorporation of dicarboxylate guests by octacalcium phosphate.

Chemical communications (Cambridge, England)

Yokoi T, Machida S, Sugahara Y, Hashimoto M, Kitaoka S.
PMID: 28573292
Chem Commun (Camb). 2017 Jun 13;53(48):6524-6527. doi: 10.1039/c7cc01169e.

Enantioselectivity by octacalcium phosphate (OCP) is revealed through the incorporation of (S)-(-)-methylsuccinic acid (MeSuc) into its crystal lattice, with hardly any (R)-(+)-MeSuc incorporated. This phenomenon clearly indicates that OCP recognizes the steric structures of guest molecules, extending chiral recognition...

Wavelength-selective and high-contrast multicolour fluorescence photoswitching in a mixture of photochromic nanoparticles.

Chemical communications (Cambridge, England)

Ishida S, Fukaminato T, Kitagawa D, Kobatake S, Kim S, Ogata T, Kurihara S.
PMID: 28636019
Chem Commun (Camb). 2017 Jul 20;53(59):8268-8271. doi: 10.1039/c7cc02938a.

Herein, we report on wavelength-selective and high-contrast multicolour fluorescence photoswitching between white-, orange-, cyan-, and dark-colours in a mixture of two distinguishable emission-coloured photochromic nanoparticles composed of different pairs of a photoswitching unit and a fluorescence unit.

A fascia lata free flap in pelvic exenteration for Fournier gangrene due to advanced rectal cancer: a case report.

Surgical case reports

Sawayama H, Miyanari N, Sugihara H, Iwagami S, Mizumoto T, Kubota T, Haga Y, Baba H.
PMID: 28550641
Surg Case Rep. 2017 Dec;3(1):74. doi: 10.1186/s40792-017-0350-y. Epub 2017 May 26.

BACKGROUND: Fournier gangrene due to advanced rectal cancer is a rapidly progressive gangrene of the perineum and buttocks. Emergency surgical debridement of necrotic tissue is crucial, and secondary surgery to resect tumors is necessary for wound healing. However, pelvic...

Isolation of a neutral boron-containing radical stabilized by a cyclic (alkyl)(amino)carbene.

Angewandte Chemie (International ed. in English)

Bissinger P, Braunschweig H, Damme A, Krummenacher I, Phukan AK, Radacki K, Sugawara S.
PMID: 24917474
Angew Chem Int Ed Engl. 2014 Jul 07;53(28):7360-3. doi: 10.1002/anie.201403514. Epub 2014 Jun 10.

Utilizing a cyclic (alkyl)(amino)carbene (CAAC) as a ligand, neutral CAAC-stabilized radicals containing a boryl functionality could be prepared by reduction of the corresponding haloborane adducts. The radical species with a duryl substituent was fully characterized by single-crystal X-ray structural...

Method for selection of soybeans tolerant to seed cracking under chilling temperatures.

Breeding science

Yamaguchi N, Yamazaki H, Ohnishi S, Suzuki C, Hagihara S, Miyoshi T, Senda M.
PMID: 24987296
Breed Sci. 2014 May;64(1):103-8. doi: 10.1270/jsbbs.64.103.

In Hokkaido, northern Japan, soybean [Glycine max (L.) Merr.] crops are damaged by cold weather. Chilling temperatures result in the appearance of cracking seeds (CS) in soybean crops, especially those grown in eastern and northern Hokkaido. Seed coats of...

Selective breeding of mice for different susceptibilities to high fat diet-induced glucose intolerance: Development of two novel mouse lines, Selectively bred Diet-induced Glucose intolerance-Prone and -Resistant.

Journal of diabetes investigation

Nagao M, Asai A, Kawahara M, Nakajima Y, Sato Y, Tanimura K, Okajima F, Takaya M, Sudo M, Takemitsu S, Harada T, Sugihara H, Oikawa S.
PMID: 24843572
J Diabetes Investig. 2012 Jun 06;3(3):245-51. doi: 10.1111/j.2040-1124.2011.00175.x.

UNLABELLED: Aims/Introduction:  The development of type 2 diabetes is primarily due to lifestyle and environmental factors, as well as genetics, as shown by familial clustering. To establish mouse lines for evaluating heritable factors determining susceptibility to diet-induced diabetes, we...

Comparison of three α-glucosidase inhibitors for glycemic control and bodyweight reduction in Japanese patients with obese type 2 diabetes.

Journal of diabetes investigation

Sugihara H, Nagao M, Harada T, Nakajima Y, Tanimura-Inagaki K, Okajima F, Tamura H, Inazawa T, Otonari T, Kawakami M, Oikawa S.
PMID: 24843762
J Diabetes Investig. 2014 Mar 23;5(2):206-12. doi: 10.1111/jdi.12135. Epub 2013 Oct 25.

AIMS/INTRODUCTION: α-Glucosidase inhibitors (αGIs) are widely used for the primary treatment of type 2 diabetes. We compared the clinical effects of three αGIs (miglitol, acarbose and voglibose) in patients with obese type 2 diabetes.MATERIALS AND METHODS: Japanese patients (n...

Showing 1 to 12 of 1175 entries