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Showing 1 to 12 of 116 entries
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Screening for antifibrotic compounds using high throughput system based on fluorescence polarization.

Biology

Stefanovic B, Stefanovic L.
PMID: 24833510
Biology (Basel). 2014 Apr 10;3(2):281-94. doi: 10.3390/biology3020281.

Fibroproliferative diseases are one of the leading causes of death worldwide. They are characterized by reactive fibrosis caused by uncontrolled synthesis of type I collagen. There is no cure for fibrosis and development of therapeutics that can inhibit collagen...

Karyotype features of trematode Himasthla elongata.

Molecular cytogenetics

Solovyeva AI, Stefanova VN, Podgornaya OI, Demin SIu.
PMID: 27134655
Mol Cytogenet. 2016 Apr 29;9:34. doi: 10.1186/s13039-016-0246-8. eCollection 2016.

BACKGROUND: Trematodes have a complex life cycle with animal host changes and alternation of parthenogenetic and hermaphrodite generations. The parthenogenetic generation of the worm (rediae) from the first intermediate host Littorina littorea was used for chromosome spreads production. Karyotype...

Substituent effects on the rate constants for the photo-Claisen rearrangement of allyl aryl ethers.

Journal of the American Chemical Society

Pincock AL, Pincock JA, Stefanova R.
PMID: 12175235
J Am Chem Soc. 2002 Aug 21;124(33):9768-78. doi: 10.1021/ja011981y.

The photochemistry of 11 substituted allyl 4-X- and 3-X-aryl ethers 3 (ArOCH2-CH=CH2) has been examined in both methanol and cyclohexane as solvents. The ethers react by the photo-Claisen rearrangement to give allyl substituted phenols as the major primary photoproducts,...

Co-precipitative pre-concentration with sodium diethyldithiocarbamate and ICP-AES determination of Se, Cu, Pb, Zn, Fe, Co, Ni, Mn, Cr and Cd in water.

Talanta

Atanassova D, Stefanova V, Russeva E.
PMID: 18967429
Talanta. 1998 Dec;47(5):1237-43. doi: 10.1016/s0039-9140(98)00211-2.

Sodium diethyldithiocarbamate in the presence of a weak oxidizing agent is used as a co-precipitative agent for the pre-concentration of Se, Cu, Pb, Zn, Fe, Co, Ni, Mn, Cr and Cd. A procedure was developed for ICP-AES determination of...

Ion-implanted polymethyl methacrylate beam splitter/coupler for 1.55 microm applications.

Applied optics

Hadjichristov GB, Stefanov IL.
PMID: 20357873
Appl Opt. 2010 Apr 01;49(10):1876-9. doi: 10.1364/AO.49.001876.

The applicability of layers of ion-implanted polymethyl methacrylate (PMMA) for beam splitting of laser light at the telecommunications wavelength of 1.55 mum is examined. Bulk PMMA is studied, subjected to low-energy (50 keV) silicon ion implantation at various ion...

Effect of dietary supplementation with different sources of selenium on growth response, selenium blood levels and meat quality of intensively finished Charolais young bulls.

Animal : an international journal of animal bioscience

Cozzi G, Prevedello P, Stefani AL, Piron A, Contiero B, Lante A, Gottardo F, Chevaux E.
PMID: 22440343
Animal. 2011 Aug;5(10):1531-8. doi: 10.1017/S1751731111000711.

The study aimed at comparing three strategies of supplementing selenium (Se) during the finishing period of Charolais young bulls: (1) administration of sodium selenite throughout the finishing (NaSe); (2) administration of an Se-enriched yeast strain (Saccharomyces cerevisiae NCYC R397)...

Miniaturized Haptic User-Interface for Heart Catheterizations - Concept and Design.

Biomedizinische Technik. Biomedical engineering

Opitz T, Neupert C, Rossner T, Stefanova N, Meiss T, Werthschützky R.
PMID: 24043109
Biomed Tech (Berl). 2013 Aug;58. doi: 10.1515/bmt-2013-4405. Epub 2013 Sep 07.

No abstract available.

Assessment of the decreased productivity of patients with diabetes type 2 in the Clinical Endocrinological Center Sofia, Bulgaria.

Pharmacy practice

Plaveev O, Dimitrova Z, Ovcharova N, Petkova V, Stefanova M, Ivanova S.
PMID: 25214910
Pharm Pract (Granada). 2006 Oct;4(4):204-7. doi: 10.4321/s1885-642x2006000400009.

This study aims to assess the influence of type 2 diabetes on the patients' productivity and quality of life. The WHO's methodology - HLQ (Health and Labor Questionnaire) is applied. Subjects were 38 patients with type 2 diabetes, diagnosed...

Could Dissimilar Phenotypic Effects of .

Molecular syndromology

Sandestig A, Green A, Jonasson J, Vogt H, Wahlström J, Pepler A, Ellnebo K, Biskup S, Stefanova M.
PMID: 30733661
Mol Syndromol. 2019 Jan;9(5):259-265. doi: 10.1159/000492267. Epub 2018 Aug 09.

The beta-actin gene encodes 1 of 6 different actin proteins. De novo heterozygous missense mutations in

Region-Specific Effects of Immunotherapy With Antibodies Targeting α-synuclein in a Transgenic Model of Synucleinopathy.

Frontiers in neuroscience

Kallab M, Herrera-Vaquero M, Johannesson M, Eriksson F, Sigvardson J, Poewe W, Wenning GK, Nordström E, Stefanova N.
PMID: 30022929
Front Neurosci. 2018 Jul 04;12:452. doi: 10.3389/fnins.2018.00452. eCollection 2018.

Synucleinopathies represent a group of neurodegenerative disorders which are characterized by intracellular accumulation of aggregated α-synuclein. α-synuclein misfolding and oligomer formation is considered a major pathogenic trigger in these disorders. Therefore, targeting α-synuclein species represents an important candidate therapeutic...

SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer's Disease-Like Pathology in OXYS Rats.

Antioxidants (Basel, Switzerland)

Muraleva NA, Stefanova NA, Kolosova NG.
PMID: 32731533
Antioxidants (Basel). 2020 Jul 28;9(8). doi: 10.3390/antiox9080676.

Alzheimer's disease (AD) is the most common type of dementia and is currently incurable, and mitogen-activated protein kinase (MAPK) p38 is implicated in the pathogenesis of AD. p38 MAPK inhibition is considered a promising strategy against AD, but there...

Defective interferon-gamma production is common in chronic pulmonary aspergillosis.

The Journal of infectious diseases

Colombo SAP, Hashad R, Denning DW, Kumararatne DS, Ceron-Gutierrez L, Barcenas-Morales G, MacDonald AS, Harris C, Doffinger R, Kosmidis C.
PMID: 34850023
J Infect Dis. 2021 Nov 29; doi: 10.1093/infdis/jiab583. Epub 2021 Nov 29.

BACKGROUND: Immune defects in chronic pulmonary aspergillosis (CPA) are poorly characterised. We compared peripheral blood cytokine profiles in patients with CPA vs healthy controls and explored the relationship with disease severity.METHODS: Interferon-gamma (IFNγ), IL-17, TNFα, IL-6, IL-12 and IL-10...

Showing 1 to 12 of 116 entries