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Showing 1 to 12 of 142 entries
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For debate: substituting placebo controls in long-term Alzheimer's prevention trials.

Alzheimer's research & therapy

Spiegel R, Berres M, Miserez AR, Monsch AU.
PMID: 21418632
Alzheimers Res Ther. 2011 Mar 21;3(2):9. doi: 10.1186/alzrt68.

INTRODUCTION: Novel compounds with potential to attenuate or stop the progression of Alzheimer's disease (AD) from its presymptomatic stage to dementia are being tested in man. The study design commonly used is the long-term randomized, placebo-controlled trial (RPCT), meaning...

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Spiegel R, Berres M, Miserez AR, et al. For debate: substituting placebo controls in long-term Alzheimer's prevention trials. Alzheimers Res Ther. 2011;3(2):9doi: 10.1186/alzrt68.
Spiegel, R., Berres, M., Miserez, A. R., Monsch, A. U. (2011). For debate: substituting placebo controls in long-term Alzheimer's prevention trials. Alzheimer's research & therapy, 3(2), 9. https://doi.org/10.1186/alzrt68
Spiegel, René, et al. "For debate: substituting placebo controls in long-term Alzheimer's prevention trials." Alzheimer's research & therapy vol. 3,2 (2011): 9. doi: https://doi.org/10.1186/alzrt68
Spiegel R, Berres M, Miserez AR, Monsch AU. For debate: substituting placebo controls in long-term Alzheimer's prevention trials. Alzheimers Res Ther. 2011 Mar 21;3(2):9. doi: 10.1186/alzrt68. PMID: 21418632; PMCID: PMC3226271.
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Novel Homozygous Missense Mutation in SPG20 Gene Results in Troyer Syndrome Associated with Mitochondrial Cytochrome c Oxidase Deficiency.

JIMD reports

Spiegel R, Soiferman D, Shaag A, Shalev S, Elpeleg O, Saada A.
PMID: 27539578
JIMD Rep. 2017;33:55-60. doi: 10.1007/8904_2016_580. Epub 2016 Aug 19.

Troyer syndrome is an autosomal recessive form of hereditary spastic paraplegia (HSP) caused by deleterious mutations in the SPG20 gene. Although the disease is associated with a loss of function mechanism of spartin, the protein encoded by SPG20, the...

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Spiegel R, Soiferman D, Shaag A, et al. Novel Homozygous Missense Mutation in SPG20 Gene Results in Troyer Syndrome Associated with Mitochondrial Cytochrome c Oxidase Deficiency. JIMD Rep. 2016;33:55-60doi: 10.1007/8904_2016_580.
Spiegel, R., Soiferman, D., Shaag, A., Shalev, S., Elpeleg, O., & Saada, A. (2017). Novel Homozygous Missense Mutation in SPG20 Gene Results in Troyer Syndrome Associated with Mitochondrial Cytochrome c Oxidase Deficiency. JIMD reports, 3355-60. https://doi.org/10.1007/8904_2016_580
Spiegel, Ronen, et al. "Novel Homozygous Missense Mutation in SPG20 Gene Results in Troyer Syndrome Associated with Mitochondrial Cytochrome c Oxidase Deficiency." JIMD reports vol. 33 (2017): 55-60. doi: https://doi.org/10.1007/8904_2016_580
Spiegel R, Soiferman D, Shaag A, Shalev S, Elpeleg O, Saada A. Novel Homozygous Missense Mutation in SPG20 Gene Results in Troyer Syndrome Associated with Mitochondrial Cytochrome c Oxidase Deficiency. JIMD Rep. 2017;33:55-60. doi: 10.1007/8904_2016_580. Epub 2016 Aug 19. PMID: 27539578; PMCID: PMC5413448.
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Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development.

Frontiers in plant science

Spiegel H, Boes A, Voepel N, Beiss V, Edgue G, Rademacher T, Sack M, Schillberg S, Reimann A, Fischer R.
PMID: 26779197
Front Plant Sci. 2015 Dec 23;6:1169. doi: 10.3389/fpls.2015.01169. eCollection 2015.

Despite decades of intensive research efforts there is currently no vaccine that provides sustained sterile immunity against malaria. In this context, a large number of targets from the different stages of the Plasmodium falciparum life cycle have been evaluated...

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Spiegel H, Boes A, Voepel N, et al. Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development. Front Plant Sci. 2015;6:1169doi: 10.3389/fpls.2015.01169.
Spiegel, H., Boes, A., Voepel, N., Beiss, V., Edgue, G., Rademacher, T., Sack, M., Schillberg, S., Reimann, A., & Fischer, R. (2015). Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development. Frontiers in plant science, 61169. https://doi.org/10.3389/fpls.2015.01169
Spiegel, Holger, et al. "Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development." Frontiers in plant science vol. 6 (2015): 1169. doi: https://doi.org/10.3389/fpls.2015.01169
Spiegel H, Boes A, Voepel N, Beiss V, Edgue G, Rademacher T, Sack M, Schillberg S, Reimann A, Fischer R. Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development. Front Plant Sci. 2015 Dec 23;6:1169. doi: 10.3389/fpls.2015.01169. eCollection 2015. PMID: 26779197; PMCID: PMC4688378.
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[In Process Citation].

Psychotherapie, Psychosomatik, medizinische Psychologie

Speidel H.
PMID: 10634065
Psychother Psychosom Med Psychol. 1999 Dec;49(12):475.

No abstract available.

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Speidel H. "Aus is's, und gar is's, und schad is's, dass's wahr is". [In Process Citation]. Psychother Psychosom Med Psychol. 1999;49(12):475
Speidel, H. (1999). "Aus is's, und gar is's, und schad is's, dass's wahr is". [In Process Citation]. Psychotherapie, Psychosomatik, medizinische Psychologie, 49(12), 475.
Speidel. ""Aus is's, und gar is's, und schad is's, dass's wahr is"." [In Process Citation]. Psychotherapie, Psychosomatik, medizinische Psychologie vol. 49,12 (1999): 475.
Speidel H. "Aus is's, und gar is's, und schad is's, dass's wahr is". [In Process Citation]. Psychother Psychosom Med Psychol. 1999 Dec;49(12):475. German. PMID: 10634065.
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Dynamics of laser-induced electroconvection pulses.

Physical review. E, Statistical, nonlinear, and soft matter physics

Giebink NC, Johnson ER, Saucedo SR, Miles EW, Vardanyan KK, Spiegel DR, Allen CC.
PMID: 15244722
Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Jun;69(6):066303. doi: 10.1103/PhysRevE.69.066303. Epub 2004 Jun 04.

We first report that, for planar nematic 4-methoxy-benzilidene-4-butylaniline (MBBA), the electroconvection threshold voltage has a nonmonotonic temperature dependence, with a well-defined minimum, and a slope of about -0.12 V/degrees C near room temperature at 70 Hz. Motivated by this...

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Giebink NC, Johnson ER, Saucedo SR, et al. Dynamics of laser-induced electroconvection pulses. Phys Rev E Stat Nonlin Soft Matter Phys. 2004;69(6):066303doi: 10.1103/PhysRevE.69.066303.
Giebink, N. C., Johnson, E. R., Saucedo, S. R., Miles, E. W., Vardanyan, K. K., Spiegel, D. R., & Allen, C. C. (2004). Dynamics of laser-induced electroconvection pulses. Physical review. E, Statistical, nonlinear, and soft matter physics, 69(6), 066303. https://doi.org/10.1103/PhysRevE.69.066303
Giebink, N C, et al. "Dynamics of laser-induced electroconvection pulses." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 69,6 (2004): 066303. doi: https://doi.org/10.1103/PhysRevE.69.066303
Giebink NC, Johnson ER, Saucedo SR, Miles EW, Vardanyan KK, Spiegel DR, Allen CC. Dynamics of laser-induced electroconvection pulses. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Jun;69(6):066303. doi: 10.1103/PhysRevE.69.066303. Epub 2004 Jun 04. PMID: 15244722.
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Differential effects of direct and indirectly acting cholinergic agonists on growth hormone release in man, and lack of effect on cortisol secretion.

Journal of neuroendocrinology

Casanueva FF, Villanueva L, Cordido F, Diaz Y, Cabranes JA, Spiegel R, Dieguez C.
PMID: 19210431
J Neuroendocrinol. 1989 Oct 01;1(5):379-82. doi: 10.1111/j.1365-2826.1989.tb00132.x.

Abstract Acetylcholine plays a key role in the modulation of growth hormone secretion. In fact, growth hormone release after provocative stimuli is blocked by muscarinic cholinergic antagonists, and conversely, indirect cholinergic agonists potentiate growth hormone secretion. To further understand...

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Casanueva FF, Villanueva L, Cordido F, et al. Differential effects of direct and indirectly acting cholinergic agonists on growth hormone release in man, and lack of effect on cortisol secretion. J Neuroendocrinol. 1989;1(5):379-82doi: 10.1111/j.1365-2826.1989.tb00132.x.
Casanueva, F. F., Villanueva, L., Cordido, F., Diaz, Y., Cabranes, J. A., Spiegel, R., & Dieguez, C. (1989). Differential effects of direct and indirectly acting cholinergic agonists on growth hormone release in man, and lack of effect on cortisol secretion. Journal of neuroendocrinology, 1(5), 379-82. https://doi.org/10.1111/j.1365-2826.1989.tb00132.x
Casanueva, F F, et al. "Differential effects of direct and indirectly acting cholinergic agonists on growth hormone release in man, and lack of effect on cortisol secretion." Journal of neuroendocrinology vol. 1,5 (1989): 379-82. doi: https://doi.org/10.1111/j.1365-2826.1989.tb00132.x
Casanueva FF, Villanueva L, Cordido F, Diaz Y, Cabranes JA, Spiegel R, Dieguez C. Differential effects of direct and indirectly acting cholinergic agonists on growth hormone release in man, and lack of effect on cortisol secretion. J Neuroendocrinol. 1989 Oct 01;1(5):379-82. doi: 10.1111/j.1365-2826.1989.tb00132.x. PMID: 19210431.
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A Case of Mania in a Patient with Systemic Lupus Erythematosus: Can Its Inflammatory Pathogenesis be Applied to Primary Mood Disorders?.

Psychiatry (Edgmont (Pa. : Township))

Spiegel DR, Holtz L, Chopra K.
PMID: 20508806
Psychiatry (Edgmont). 2010 Apr;7(4):31-6.

Systemic lupus erythematosus is a chronic inflammatory condition caused by an autoimmune disease. Systemic lupus erythematosus has been described as inducing neuropsychiatric symptoms, including mania and psychosis, in approximately 14 to 80 percent of systemic lupus erythematosus patients. We...

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Spiegel DR, Holtz L, Chopra K. A Case of Mania in a Patient with Systemic Lupus Erythematosus: Can Its Inflammatory Pathogenesis be Applied to Primary Mood Disorders?. Psychiatry (Edgmont). 2010;7(4):31-6
Spiegel, D. R., Holtz, L., & Chopra, K. (2010). A Case of Mania in a Patient with Systemic Lupus Erythematosus: Can Its Inflammatory Pathogenesis be Applied to Primary Mood Disorders?. Psychiatry (Edgmont (Pa. : Township)), 7(4), 31-6.
Spiegel, David R, et al. "A Case of Mania in a Patient with Systemic Lupus Erythematosus: Can Its Inflammatory Pathogenesis be Applied to Primary Mood Disorders?." Psychiatry (Edgmont (Pa. : Township)) vol. 7,4 (2010): 31-6.
Spiegel DR, Holtz L, Chopra K. A Case of Mania in a Patient with Systemic Lupus Erythematosus: Can Its Inflammatory Pathogenesis be Applied to Primary Mood Disorders?. Psychiatry (Edgmont). 2010 Apr;7(4):31-6. PMID: 20508806; PMCID: PMC2877619.
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PULMONARY INFARCTION AND EMBOLISM.

Annals of surgery

Farr CE, Spiegel R.
PMID: 17866072
Ann Surg. 1929 Apr;89(4):481-511. doi: 10.1097/00000658-192904000-00001.

No abstract available.

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Farr CE, Spiegel R. PULMONARY INFARCTION AND EMBOLISM. Ann Surg. 1929;89(4):481-511doi: 10.1097/00000658-192904000-00001.
Farr, C. E., & Spiegel, R. (1929). PULMONARY INFARCTION AND EMBOLISM. Annals of surgery, 89(4), 481-511. https://doi.org/10.1097/00000658-192904000-00001
Farr, C E, and Spiegel, R. "PULMONARY INFARCTION AND EMBOLISM." Annals of surgery vol. 89,4 (1929): 481-511. doi: https://doi.org/10.1097/00000658-192904000-00001
Farr CE, Spiegel R. PULMONARY INFARCTION AND EMBOLISM. Ann Surg. 1929 Apr;89(4):481-511. doi: 10.1097/00000658-192904000-00001. PMID: 17866072; PMCID: PMC1398711.
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Neurosarcoidosis and the complexity in its differential diagnoses: a review.

Innovations in clinical neuroscience

Spiegel DR, Morris K, Rayamajhi U.
PMID: 22666636
Innov Clin Neurosci. 2012 Apr;9(4):10-6.

While uncommon, neurosarcoidosis has been reported to present similarly to schizophrenia, with auditory hallucinations and delusions. We review the evaluation and work-up of neurosarcoidosis and discuss the differential diagnoses of these psychotic symptoms.

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Spiegel DR, Morris K, Rayamajhi U. Neurosarcoidosis and the complexity in its differential diagnoses: a review. Innov Clin Neurosci. 2012;9(4):10-6
Spiegel, D. R., Morris, K., & Rayamajhi, U. (2012). Neurosarcoidosis and the complexity in its differential diagnoses: a review. Innovations in clinical neuroscience, 9(4), 10-6.
Spiegel, David R, et al. "Neurosarcoidosis and the complexity in its differential diagnoses: a review." Innovations in clinical neuroscience vol. 9,4 (2012): 10-6.
Spiegel DR, Morris K, Rayamajhi U. Neurosarcoidosis and the complexity in its differential diagnoses: a review. Innov Clin Neurosci. 2012 Apr;9(4):10-6. PMID: 22666636; PMCID: PMC3366456.
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Developing a standardized approach to the assessment of pain in children and youth presenting to pediatric rheumatology providers: a Delphi survey and consensus conference process followed by feasibility testing.

Pediatric rheumatology online journal

Stinson JN, Connelly M, Jibb LA, Schanberg LE, Walco G, Spiegel LR, Tse SM, Chalom EC, Chira P, Rapoff M.
PMID: 22490427
Pediatr Rheumatol Online J. 2012 Apr 10;10(1):7. doi: 10.1186/1546-0096-10-7.

BACKGROUND: Pain in children with rheumatic conditions such as arthritis is common. However, there is currently no standardized method for the assessment of this pain in children presenting to pediatric rheumatologists. A more consistent and comprehensive approach is needed...

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Stinson JN, Connelly M, Jibb LA, et al. Developing a standardized approach to the assessment of pain in children and youth presenting to pediatric rheumatology providers: a Delphi survey and consensus conference process followed by feasibility testing. Pediatr Rheumatol Online J. 2012;10(1):7doi: 10.1186/1546-0096-10-7.
Stinson, J. N., Connelly, M., Jibb, L. A., Schanberg, L. E., Walco, G., Spiegel, L. R., Tse, S. M., Chalom, E. C., Chira, P., & Rapoff, M. (2012). Developing a standardized approach to the assessment of pain in children and youth presenting to pediatric rheumatology providers: a Delphi survey and consensus conference process followed by feasibility testing. Pediatric rheumatology online journal, 10(1), 7. https://doi.org/10.1186/1546-0096-10-7
Stinson, Jennifer N, et al. "Developing a standardized approach to the assessment of pain in children and youth presenting to pediatric rheumatology providers: a Delphi survey and consensus conference process followed by feasibility testing." Pediatric rheumatology online journal vol. 10,1 (2012): 7. doi: https://doi.org/10.1186/1546-0096-10-7
Stinson JN, Connelly M, Jibb LA, Schanberg LE, Walco G, Spiegel LR, Tse SM, Chalom EC, Chira P, Rapoff M. Developing a standardized approach to the assessment of pain in children and youth presenting to pediatric rheumatology providers: a Delphi survey and consensus conference process followed by feasibility testing. Pediatr Rheumatol Online J. 2012 Apr 10;10(1):7. doi: 10.1186/1546-0096-10-7. PMID: 22490427; PMCID: PMC3366881.
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Resorbable ciprofloxacin/polyglycol acid carrier in the local therapy of chronic osteitis.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Winckler S, Overbeck JP, Meffert R, Törmälä P, Spiegel HU.
PMID: 24193334
Eur J Orthop Surg Traumatol. 1995 Dec;5(2):133-7. doi: 10.1007/BF02716257.

Polyglycolic test cylinders (PGA) of different sizes and with a different amount of Ciprofloxacin were synthezised and tested in vitro. The monofil 3,2×5 mm sized cylinders containing 3 mg of Ciprofloxacin showed the best release of the antibiotic up...

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Winckler S, Overbeck JP, Meffert R, et al. Resorbable ciprofloxacin/polyglycol acid carrier in the local therapy of chronic osteitis. Eur J Orthop Surg Traumatol. 1995;5(2):133-7doi: 10.1007/BF02716257.
Winckler, S., Overbeck, J. P., Meffert, R., Törmälä, P., & Spiegel, H. U. (1995). Resorbable ciprofloxacin/polyglycol acid carrier in the local therapy of chronic osteitis. European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 5(2), 133-7. https://doi.org/10.1007/BF02716257
Winckler, S, et al. "Resorbable ciprofloxacin/polyglycol acid carrier in the local therapy of chronic osteitis." European journal of orthopaedic surgery & traumatology : orthopedie traumatologie vol. 5,2 (1995): 133-7. doi: https://doi.org/10.1007/BF02716257
Winckler S, Overbeck JP, Meffert R, Törmälä P, Spiegel HU. Resorbable ciprofloxacin/polyglycol acid carrier in the local therapy of chronic osteitis. Eur J Orthop Surg Traumatol. 1995 Dec;5(2):133-7. doi: 10.1007/BF02716257. PMID: 24193334.
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Reducing health risks of physical inactivity by cardiac rehabilitation.

Nature reviews. Cardiology

Spiegel R.
PMID: 23044727
Nat Rev Cardiol. 2012 Dec;9(12):733. doi: 10.1038/nrcardio.2012.115-c1. Epub 2012 Oct 09.

No abstract available.

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Spiegel R. Reducing health risks of physical inactivity by cardiac rehabilitation. Nat Rev Cardiol. 2012;9(12):733doi: 10.1038/nrcardio.2012.115-c1.
Spiegel, R. (2012). Reducing health risks of physical inactivity by cardiac rehabilitation. Nature reviews. Cardiology, 9(12), 733. https://doi.org/10.1038/nrcardio.2012.115-c1
Spiegel, Rainer. "Reducing health risks of physical inactivity by cardiac rehabilitation." Nature reviews. Cardiology vol. 9,12 (2012): 733. doi: https://doi.org/10.1038/nrcardio.2012.115-c1
Spiegel R. Reducing health risks of physical inactivity by cardiac rehabilitation. Nat Rev Cardiol. 2012 Dec;9(12):733. doi: 10.1038/nrcardio.2012.115-c1. Epub 2012 Oct 09. PMID: 23044727.
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Showing 1 to 12 of 142 entries