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Showing 1 to 12 of 236 entries
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Total Synthesis of (-)-Rhazinilam and Formal Synthesis of (+)-Eburenine and (+)-Aspidospermidine: Asymmetric Cu-Catalyzed Propargylic Substitution.

Organic letters

Shemet A, Carreira EM.
PMID: 28968107
Org Lett. 2017 Oct 20;19(20):5529-5532. doi: 10.1021/acs.orglett.7b02619. Epub 2017 Oct 02.

A total synthesis of (-)-rhazinilam and formal syntheses of (+)-eburenine and (+)-aspidospermidine that rely on a copper(I)-catalyzed asymmetric propargylic substitution as the key step are reported. A salient feature of the reaction is the asymmetric construction of a quaternary...

Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity.

Oncotarget

Christianson HC, Menard JA, Chandran VI, Bourseau-Guilmain E, Shevela D, Lidfeldt J, Månsson AS, Pastorekova S, Messinger J, Belting M.
PMID: 28978009
Oncotarget. 2017 Apr 07;8(40):66960-66974. doi: 10.18632/oncotarget.16921. eCollection 2017 Sep 15.

Aggressive cancers are characterized by hypoxia, which is a key driver of tumor development and treatment resistance. Proteins specifically expressed in the hypoxic tumor microenvironment thus represent interesting candidates for targeted drug delivery strategies. Carbonic anhydrase (CAIX) has been...

Changes in cerebral vascular reactivity and structure following prolonged exposure to high altitude in humans.

Physiological reports

Foster GE, Davies-Thompson J, Dominelli PB, Heran MK, Donnelly J, duManoir GR, Ainslie PN, Rauscher A, Sheel AW.
PMID: 26660556
Physiol Rep. 2015 Dec;3(12). doi: 10.14814/phy2.12647.

Although high-altitude exposure can lead to neurocognitive impairment, even upon return to sea level, it remains unclear the extent to which brain volume and regional cerebral vascular reactivity (CVR) are altered following high-altitude exposure. The purpose of this study...

Risk Factors and Risk-Based Protective Factors for Violent Offending: A Study of Young Victorians.

Journal of criminal justice

Hemphill SA, Heerde JA, Scholes-Balog KE.
PMID: 27325904
J Crim Justice. 2016 Jun;45:94-100. doi: 10.1016/j.jcrimjus.2016.02.012. Epub 2016 Feb 15.

PURPOSE: The present study aims to examine risk factors and risk-based and interactive protective factors for violent offending in a group of 437 young Australians.METHODS: Participants were recruited into the study when they were in Grade 5 (10-11 years)...

Breaking bad news: A communication competency for ophthalmology training programs.

Survey of ophthalmology

Hilkert SM, Cebulla CM, Jain SG, Pfeil SA, Benes SC, Robbins SL.
PMID: 27134009
Surv Ophthalmol. 2016 Nov - Dec;61(6):791-798. doi: 10.1016/j.survophthal.2016.04.005. Epub 2016 Apr 29.

As the ophthalmology accreditation system undergoes major changes, training programs must evaluate residents in the 6 core competencies, including appropriately communicating bad news. Although the literature is replete with recommendations for breaking bad news across various non-ophthalmology specialties, no...

Size and aspect ratio control of Pd₂Sn nanorods and their water denitration properties.

Langmuir : the ACS journal of surfaces and colloids

Luo Z, Ibáñez M, Antolín AM, Genç A, Shavel A, Contreras S, Medina F, Arbiol J, Cabot A.
PMID: 25751745
Langmuir. 2015 Apr 07;31(13):3952-7. doi: 10.1021/la504906q. Epub 2015 Mar 23.

Monodisperse Pd2Sn nanorods with tuned size and aspect ratio were prepared by co-reduction of metal salts in the presence of trioctylphosphine, amine, and chloride ions. Asymmetric Pd2Sn nanostructures were achieved by the selective desorption of a surfactant mediated by...

Administration of intrapulmonary sodium polyacrylate to induce lung injury for the development of a porcine model of early acute respiratory distress syndrome.

Intensive care medicine experimental

Henderson WR, Barnbrook J, Dominelli PB, Griesdale DE, Arndt T, Molgat-Seon Y, Foster G, Ackland GL, Xu J, Ayas NT, Sheel AW.
PMID: 26266906
Intensive Care Med Exp. 2014 Dec;2(1):5. doi: 10.1186/2197-425X-2-5. Epub 2014 Feb 26.

BACKGROUND: The loss of alveolar epithelial and endothelial integrity is a central component in acute respiratory distress syndrome (ARDS); however, experimental models investigating the mechanisms of epithelial injury are lacking. The purpose of the present study was to design...

NH₃ treatment of TiO₂ nanotubes: from N-doping to semimetallic conductivity.

Chemical communications (Cambridge, England)

Al-Thabaiti SA, Hahn R, Liu N, Kirchgeorg R, So S, Schmuki P, Basahel SN, Bawaked SM.
PMID: 24918106
Chem Commun (Camb). 2014 Jul 28;50(59):7960-3. doi: 10.1039/c4cc02069c.

In the present work we show that a suitable high temperature ammonia treatment allows for the conversion of single-walled TiO2 nanotube arrays not only to a N-doped photoactive anatase material (which is already well established), but even further into...

Time multiplexing superresolution based on interference grating projection.

Applied optics

Shemer A, Zalevsky Z, Mendlovic D, Konforti N, Marom E.
PMID: 12502295
Appl Opt. 2002 Dec 10;41(35):7397-404. doi: 10.1364/ao.41.007397.

In a previous work done by the authors, it was shown that the superresolution concept based on two moving gratings could be effected by a physical grating attached to the object and a virtual grating. This concept was shown...

[Vascular collaterals of the lung].

Revista latinoamericana de anatomia patologica

COSTERO I, BARROSO-MOGUEL R, CONTRERASR, CHEVEZ A, MONROY G, QUIROZ A.
PMID: 13881630
Rev Latinoam Anat Patol. 1960 Jan-Dec;4:5-11.

No abstract available.

Report on the Company's operations in 1946.

Nordisk medicin

SCHEEL A.
PMID: 18862732
Nord Med. 1948 Mar 12;37(11):557.

No abstract available.

The pipeline. Igniting girls' interest in science.

Science (New York, N.Y.)

Tucker SA, Hanuscin DL, Bearnes CJ.
PMID: 18356508
Science. 2008 Mar 21;319(5870):1621-2. doi: 10.1126/science.1153261.

No abstract available.

Showing 1 to 12 of 236 entries