Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 198 entries
Sorted by: Best Match Show Resources per page
Association between maternal education and objectively measured physical activity and sedentary time in adolescents

Non-school settings

Cooper AR, Ekelund U, Sherar LB.
GSID: 7q0asgmLLucJ
LB Sherar, TP Griffin, U Ekelund, AR Cooper… - J Epidemiol …, 2016 - jech.bmj.com

Background Investigating socioeconomic variation in physical activity (PA) and sedentary time is important as it may represent a pathway by which socioeconomic position (SEP) …

Antenna Biphenols: Development of Extended Wavelength Chiroptical Reporters.

The Journal of organic chemistry

Bentley KW, Joyce LA, Sherer EC, Sheng H, Wolf C, Welch CJ.
PMID: 26756165
J Org Chem. 2016 Feb 05;81(3):1185-91. doi: 10.1021/acs.joc.5b02716. Epub 2016 Jan 26.

Molecular hosts capable of chiroptical sensing of complexed guest molecules offer an attractive alternative to conventional methods for the analysis of the absolute configuration and enantiopurity. Sensors based on the Pfeiffer effect rely on complexation-driven asymmetric transformation of the...

Constraining Solar Wind Heating Processes by Kinetic Properties of Heavy Ions.

Physical review letters

Tracy PJ, Kasper JC, Raines JM, Shearer P, Gilbert JA, Zurbuchen TH.
PMID: 27391732
Phys Rev Lett. 2016 Jun 24;116(25):255101. doi: 10.1103/PhysRevLett.116.255101. Epub 2016 Jun 21.

We analyze the heavy ion components (A>4  amu) in collisionally young solar wind plasma and show that there is a clear, stable dependence of temperature on mass, probably reflecting the conditions in the solar corona. We consider both linear...

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes.

ACS medicinal chemistry letters

Guo L, Parker DL, Zang Y, Sweis RF, Liu W, Sherer EC, Buist N, Terebetski J, Kelly T, Bugianesi R, Priest BT, Dingley KH, Li X, Mitelman S, Salituro G, Trujillo ME, Pachanski M, Kirkland M, Powles MA, Eiermann GJ, Feng Y, Shang J, Howard AD, Ujjainwalla F, Sinz CJ, Debenham JS, Edmondson SD, Nargund RP, Hagmann WK, Li D.
PMID: 27994747
ACS Med Chem Lett. 2016 Oct 12;7(12):1107-1111. doi: 10.1021/acsmedchemlett.6b00314. eCollection 2016 Dec 08.

GPR142 has been identified as a potential glucose-stimulated insulin secretion (GSIS) target for the treatment of type 2 diabetes mellitus (T2DM). A class of triazole GPR142 agonists was discovered through a high throughput screen. The lead compound

Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons.

Molecular metabolism

Sun J, Gao Y, Yao T, Huang Y, He Z, Kong X, Yu KJ, Wang RT, Guo H, Yan J, Chang Y, Chen H, Scherer PE, Liu T, Williams KW.
PMID: 27689001
Mol Metab. 2016 Aug 18;5(10):882-891. doi: 10.1016/j.molmet.2016.08.007. eCollection 2016 Oct.

OBJECTIVE: Adiponectin receptors (AdipoRs) are located on neurons of the hypothalamus involved in metabolic regulation - including arcuate proopiomelanocortin (Pomc) and Neuropeptide Y/Agouti-related peptide (NPY/AgRP) neurons. AdipoRs play a critical role in regulating glucose and fatty acid metabolism by...

A Semiempirical Quantum Model for Hydrogen-Bonded Nucleic Acid Base Pairs.

Journal of chemical theory and computation

Giese TJ, Sherer EC, Cramer CJ, York DM.
PMID: 26631671
J Chem Theory Comput. 2005 Nov;1(6):1275-85. doi: 10.1021/ct050102l.

An exploratory semiempirical Hamiltonian (PM3BP) is developed to model hydrogen bonding in nucleic acid base pairs. The PM3BP Hamiltonian is a novel reparametrization of the PM3 Hamiltonian designed to reproduce experimental base pair dimer enthalpies and high-level density-functional results....

Seismic Velocity and Density Jumps Across the 410- and 660-Kilometer Discontinuities.

Science (New York, N.Y.)

Shearer PM, Flanagan MP.
PMID: 10477514
Science. 1999 Sep 03;285(5433):1545-1548. doi: 10.1126/science.285.5433.1545.

The average seismic velocity and density jumps across the 410- and 660-kilometer discontinuities in the upper mantle were determined by modeling the observed range dependence in long-period seismic wave arrivals that reflect off of these interfaces. The preliminary reference...

The physician's role in the social security disability program.

Journal of the South Carolina Medical Association

SHERER PG.
PMID: 13599149
J S C Med Assoc. 1958 Nov;54(11):421-3.

No abstract available.

A high-frequency secondary event during the 2004 Parkfield earthquake.

Science (New York, N.Y.)

Allmann BP, Shearer PM.
PMID: 18033878
Science. 2007 Nov 23;318(5854):1279-83. doi: 10.1126/science.1146537.

By using seismic records of the 2004 magnitude 6.0 Parkfield earthquake, we identified a burst of high-frequency seismic radiation that occurred about 13 kilometers northwest of the hypocenter and 5 seconds after rupture initiation. We imaged this event in...

Quality of life information and trust in physicians among families of children with life-limiting conditions.

Patient related outcome measures

Huang IC, Kenzik KM, Sanjeev TY, Shearer PD, Revicki DA, Nackashi JA, Shenkman EA.
PMID: 21760753
Patient Relat Outcome Meas. 2010 Oct;2010(1):141-148. doi: 10.2147/prom.s12564.

PURPOSE: To examine information that parents of children with life-limiting conditions want to discuss with children's physicians to assist decision-making, and whether the desire for this information is associated with parents' trust in physicians. STUDY DESIGN: A cross-sectional study...

Depression care management: can employers purchase improved outcomes?.

Depression research and treatment

Rost K, Marshall D, Shearer B, Dietrich AJ.
PMID: 21738872
Depress Res Treat. 2011;2011:942519. doi: 10.1155/2011/942519. Epub 2011 Jun 08.

Fourteen vendors are currently selling depression care management products to US employers after randomized trials demonstrate improved work outcomes. The research team interviewed 10 (71.4%) of these vendors to compare their products to four key components of interventions demonstrated...

Adiponectin, driver or passenger on the road to insulin sensitivity?.

Molecular metabolism

Ye R, Scherer PE.
PMID: 24049728
Mol Metab. 2013 Apr 19;2(3):133-41. doi: 10.1016/j.molmet.2013.04.001.

Almost 20 years have passed since the first laboratory evidence emerged that an abundant message encoding a protein with homology to the C1q superfamily is highly specifically expressed in adipocytes. At this stage, we refer to this protein as...

Showing 1 to 12 of 198 entries