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Showing 1 to 12 of 14 entries
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Extended-Release Guaifenesin/Pseudoephedrine Hydrochloride for Symptom Relief in Support of a Wait-and-See Approach for the Treatment of Acute Upper Respiratory Tract Infections: A Randomized, Double-Blind, Placebo-Controlled Study.

Current therapeutic research, clinical and experimental

Septimus EJ, Albrecht HH, Solomon G, Shea T, Guenin EP.
PMID: 28761581
Curr Ther Res Clin Exp. 2017 Apr 28;84:54-61. doi: 10.1016/j.curtheres.2017.04.004. eCollection 2017.

BACKGROUND: Despite the well-known fact that antibiotics (AB) are not effective against viruses, many patients ask for - and all too often doctors provide - AB for treating URTIs. Over-prescribing of AB is one of the key causes for...

Impact of Risk Adjustment Using Clinical vs Administrative Data on Hospital Sepsis Mortality Comparisons.

Open forum infectious diseases

Rhee C, Li Z, Wang R, Song Y, Kadri SS, Septimus EJ, Chen HC, Fram D, Jin R, Poland R, Sands K, Klompas M.
PMID: 32617377
Open Forum Infect Dis. 2020 Jun 25;7(6):ofaa213. doi: 10.1093/ofid/ofaa213. eCollection 2020 Jun.

BACKGROUND: A reliable risk-adjusted sepsis outcome measure could complement current national process metrics by identifying outlier hospitals and catalyzing additional improvements in care. However, it is unclear whether integrating clinical data into risk adjustment models identifies similar high- and...

Risk Adjustment for Sepsis Mortality to Facilitate Hospital Comparisons Using Centers for Disease Control and Prevention's Adult Sepsis Event Criteria and Routine Electronic Clinical Data.

Critical care explorations

Rhee C, Wang R, Song Y, Zhang Z, Kadri SS, Septimus EJ, Fram D, Jin R, Poland RE, Hickok J, Sands K, Klompas M.
PMID: 32166230
Crit Care Explor. 2019 Oct 14;1(10):e0049. doi: 10.1097/CCE.0000000000000049. eCollection 2019 Oct.

Variability in hospital-level sepsis mortality rates may be due to differences in case mix, quality of care, or diagnosis and coding practices. Centers for Disease Control and Prevention's Adult Sepsis Event definition could facilitate objective comparisons of sepsis mortality...

Epidemic .

Open forum infectious diseases

Endres BT, Begum K, Sun H, Walk ST, Memariani A, Lancaster C, Gonzales-Luna AJ, Dotson KM, Bassères E, Offiong C, Tupy S, Kuper K, Septimus E, Arafat R, Alam MJ, Zhao Z, Hurdle JG, Savidge TC, Garey KW.
PMID: 30793006
Open Forum Infect Dis. 2019 Feb 09;6(2):ofz013. doi: 10.1093/ofid/ofz013. eCollection 2019 Feb.

No abstract available.

Moving toward elimination of healthcare-associated infections: a call to action.

Infection control and hospital epidemiology

Cardo D, Dennehy PH, Halverson P, Fishman N, Kohn M, Murphy CL, Whitley RJ, Brennan PJ, Bright J, Curry C, Graham D, Haerum B, Kainer M, Kaye K, Lundstrom T, Richards C, Tomlinson L, Skillen EL, Streed S, Young M, Septimus E.
PMID: 20929300
Infect Control Hosp Epidemiol. 2010 Nov;31(11):1101-5. doi: 10.1086/656912.

No abstract available.

The Impact of COVID-19 on Healthcare-Associated Infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Baker MA, Sands KE, Huang SS, Kleinman K, Septimus EJ, Varma N, Blanchard J, Poland RE, Coady MH, Yokoe DS, Fraker S, Froman A, Moody J, Goldin L, Isaacs A, Kleja K, Korwek KM, Stelling J, Clark A, Platt R, Perlin JB.
PMID: 34370014
Clin Infect Dis. 2021 Aug 09; doi: 10.1093/cid/ciab688. Epub 2021 Aug 09.

BACKGROUND: The profound changes wrought by COVID-19 on routine hospital operations may have influenced performance on hospital measures, including healthcare-associated infections (HAIs). We aimed to evaluate the association between COVID-19 surges and HAI and cluster rates.METHODS: In 148 HCA...

A compendium of strategies to prevent healthcare-associated infections in acute care hospitals: 2014 updates.

Infection control and hospital epidemiology

Yokoe DS, Anderson DJ, Berenholtz SM, Calfee DP, Dubberke ER, Ellingson KD, Gerding DN, Haas JP, Kaye KS, Klompas M, Lo E, Marschall J, Mermel LA, Nicolle LE, Salgado CD, Bryant K, Classen D, Crist K, Deloney VM, Fishman NO, Foster N, Goldmann DA, Humphreys E, Jernigan JA, Padberg J, Perl TM, Podgorny K, Septimus EJ, VanAmringe M, Weaver T, Weinstein RA, Wise R, Maragakis LL.
PMID: 25376067
Infect Control Hosp Epidemiol. 2014 Sep;35:S21-31. doi: 10.1017/s0899823x00193833.

Since the publication of "A Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals" in 2008, prevention of healthcare-associated infections (HAIs) has become a national priority. Despite improvements, preventable HAIs continue to occur. The 2014 updates to...

Prevention of Device-Related Healthcare-Associated Infections.

F1000Research

Septimus EJ, Moody J.
PMID: 26918162
F1000Res. 2016 Jan 14;5. doi: 10.12688/f1000research.7493.1. eCollection 2016.

Healthcare-associated infections (HAIs) are a leading cause of morbidity and mortality in hospitalized patients. Up to 15% of patients develop an infection while hospitalized in the United States, which accounts for approximately 1.7 million HAIs, 99,000 deaths annually and...

Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems.

Healthcare (Amsterdam, Netherlands)

Larson EB, Tachibana C, Thompson E, Coronado GD, DeBar L, Dember LM, Honda S, Huang SS, Jarvik JG, Nelson C, Septimus E, Simon G, Johnson KE.
PMID: 27637816
Healthc (Amst). 2016 Sep;4(3):138-41. doi: 10.1016/j.hjdsi.2015.07.005. Epub 2015 Jul 29.

Pragmatic clinical trials are increasingly common because they have the potential to yield findings that are directly translatable to real-world healthcare settings. Pragmatic clinical trials need to integrate research into clinical workflow without placing an undue burden on the...

African Tick-Bite Fever: A Case Report.

Journal of travel medicine

Ericsson CD, Long J, Septimus E.
PMID: 9815517
J Travel Med. 1997 Dec 01;4(4):197. doi: 10.1111/j.1708-8305.1997.tb00822.x.

Mediterranean spotted fever, a disease caused by Rickettsia conorii, is a well-described syndrome among travelers returning from Africa.1 In the present issue of Journal of Travel Medicine2 a case of Rickettsia conorii disease is presented and discussed in context...

Antimicrobial stewardship-qualitative and quantitative outcomes: the role of measurement.

Current infectious disease reports

Septimus E.
PMID: 25230602
Curr Infect Dis Rep. 2014 Nov;16(11):433. doi: 10.1007/s11908-014-0433-x.

Overuse and misuse of antibiotics have contributed to the growing problem of antimicrobial resistance and serious side effects including Clostridium difficile infection. The Centers for Disease Control and Prevention estimates that more than 2 million people are infected by...

Maintaining the momentum of change: the role of the 2014 updates to the compendium in preventing healthcare-associated infections.

Infection control and hospital epidemiology

Septimus E, Yokoe DS, Weinstein RA, Perl TM, Maragakis LL, Berenholtz SM.
PMID: 25376063
Infect Control Hosp Epidemiol. 2014 Sep;35:S6-9.

Preventing healthcare-associated infections (HAIs) is a national priority. Although substantial progress has been achieved, considerable deficiencies remain in our ability to efficiently and effectively translate existing knowledge about HAI prevention into reliable, sustainable, widespread practice. "A Compendium of Strategies...

Showing 1 to 12 of 14 entries