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Showing 1 to 12 of 35 entries
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In JNMA 100 years ago: the 1908 annual meeting.

Journal of the National Medical Association

Savitt TL.
PMID: 20191929
J Natl Med Assoc. 2010 Feb;102(2):140-3. doi: 10.1016/s0027-9684(15)30516-2.

No abstract available.

eIF5 is a dual function GAP and GDI for eukaryotic translational control.

Small GTPases

Jennings MD, Pavitt GD.
PMID: 21686265
Small GTPases. 2010 Sep;1(2):118-123. doi: 10.4161/sgtp.1.2.13783.

We recently showed in a publication in Nature that the eukaryotic translation initiation factor eIF5 has a second regulatory function and is a GDI (GDP dissociation inhibitor) in addition to its previously characterized role as a GAP (GTPase accelerating...

Levodopa-induced dyskinesias in mitochondrial membrane protein-associated neurodegeneration.

Neurology. Clinical practice

Savitt D, Jankovic J.
PMID: 30859014
Neurol Clin Pract. 2019 Feb;9(1):e7-e9. doi: 10.1212/CPJ.0000000000000577.

No abstract available.

Women with chronic constipation have more bothersome urogenital symptoms.

Techniques in coloproctology

Ortega MV, Kim Y, Hung K, James K, Savitt L, Von Bargen E, Bordeianou LG, Weinstein MM.
PMID: 34820751
Tech Coloproctol. 2021 Nov 24; doi: 10.1007/s10151-021-02518-4. Epub 2021 Nov 24.

BACKGROUND: The aim of our study was to characterize urogenital symptoms in women with and without constipation, and by severity of constipation.METHODS: This was a retrospective cohort study conducted at a pelvic floor disorder center in a tertiary healthcare...

Comparison of Mini-Mental State Examination and Montreal Cognitive Assessment Ratings Across Levels of Parkinson's Disease Severity.

Journal of Parkinson's disease

Snyder A, Gruber-Baldini AL, Rainer von Coelln F, Savitt JM, Reich SG, Armstrong MJ, Shulman LM, Wiers RW, Bartholow BD.
PMID: 34366371
J Parkinsons Dis. 2021;11(4):1995-2003. doi: 10.3233/JPD-212705.

BACKGROUND: Cognitive impairment (CI) is common in Parkinson's disease (PD) and an important cause of disability. Screening facilitates early detection of CI and has implications for management. Preclinical disability is when patients have functional limitations but maintain independence through...

Living and Leaving Life on One's Own Terms: Certain Legal Rights of Older Adults and Persons with Disabilities.

Topics in stroke rehabilitation

Slavitt EB, LaBant TM.
PMID: 27620152
Top Stroke Rehabil. 1996 Jan;2(4):44-53. doi: 10.1080/10749357.1996.11754092.

While attention has been focused on granting equal rights based on race, religion, and gender, the rights of older and disabled persons have been overlooked for many years. Existing laws were of limited scope or were not enforced. However,...

In Vitro-Administered Dexamethasone Suppresses T Cell Function With Reversal by Interleukin-7 in Coronavirus Disease 2019.

Critical care explorations

Mazer MB, Davitt E, Turnbull IR, Caldwell CC, Brakenridge SC, Remy KE, Hotchkiss RS.
PMID: 33834168
Crit Care Explor. 2021 Apr 02;3(4):e0378. doi: 10.1097/CCE.0000000000000378. eCollection 2021 Apr.

OBJECTIVES: Corticosteroid therapy has become standard of care therapy for hospitalized patients infected with the severe acute respiratory syndrome coronavirus-2 global pandemic-causing virus. Whereas systemic inflammation is a notably important feature in coronavirus disease 2019 pathogenesis, adaptive immune suppression...

American Association for the History of Medicine: Report of the Seventy-fourth Annual Meeting.

Bulletin of the history of medicine

Savitt TL.
PMID: 11740119
Bull Hist Med. 2001;75(3):535-551. doi: 10.1353/bhm.2001.0148.

No abstract available.

Effects of risperidone on auditory event-related potentials in schizophrenia.

The international journal of neuropsychopharmacology

Umbricht D, Javitt D, Novak G, Bates J, Pollack S, Lieberman J, Kane J.
PMID: 11285146
Int J Neuropsychopharmacol. 1999 Dec;2(4):299-304. doi: 10.1017/S1461145799001595.

Schizophrenia is associated with cognitive deficits for which treatments remain elusive. The effects of risperidone (an antipsychotic differing in some of its pharmacological properties from typical agents) on cognitive deficits have not been extensively investigated. Mismatch negativity (MMN), N2...

Learning About Sickle Cell: The Patient in Early Sickle Cell Disease Case Reports, 1910-1933.

Journal of the National Medical Association

Savitt TL.
PMID: 26744113
J Natl Med Assoc. Summer 2014;106(1):31-41. doi: 10.1016/S0027-9684(15)30068-7.

Case reports of sickle cell disease (SCD) from its discovery in 1910 to 1933 provide glimpses into the disease's impact on patients and families. Attending physicians, trying to understand the pathophysiology of and treatments for this newly recognized disease,...

Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis.

Cellular and molecular gastroenterology and hepatology

Sünderhauf A, Hicken M, Schlichting H, Skibbe K, Ragab M, Raschdorf A, Hirose M, Schäffler H, Bokemeyer A, Bettenworth D, Savitt AG, Perner S, Ibrahim S, Peerschke EI, Ghebrehiwet B, Derer S, Sina C.
PMID: 33515804
Cell Mol Gastroenterol Hepatol. 2021;12(1):229-250. doi: 10.1016/j.jcmgh.2021.01.017. Epub 2021 Jan 27.

BACKGROUND & AIMS: Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction have been attributed to the pathology of ulcerative colitis (UC). We hypothesized that p32/gC1qR/HABP1,...

Weight loss and weight gain in Parkinson disease.

Parkinsonism & related disorders

Ghourchian S, Gruber-Baldini AL, Shakya S, Herndon J, Reich SG, von Coelln R, Savitt JM, Shulman LM.
PMID: 33465545
Parkinsonism Relat Disord. 2021 Feb;83:31-36. doi: 10.1016/j.parkreldis.2020.12.018. Epub 2021 Jan 12.

INTRODUCTION: Parkinson disease (PD) has been associated with both weight loss and gain in different stages of the disease. Our study aimed to determine the prevalence and associations with weight change over two years based on 3% and 5%...

Showing 1 to 12 of 35 entries