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Data on optical coherence tomography guidance for the management of angiographically intermediate left main bifurcation lesions.

Data in brief

Dato I, Burzotta F, Trani C, Romano A, Paraggio L, Aurigemma C, Porto I, Maria Leone A, Niccoli G, Crea F.
PMID: 28913391
Data Brief. 2017 Sep 05;14:635-638. doi: 10.1016/j.dib.2017.08.015. eCollection 2017 Oct.

The data presented in this article are related to the research article entitled "Optical coherence tomography guidance for the management of angiographically intermediate left main bifurcation lesions: early clinical experience" [1]. In this article we reports details about our...

Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts.

BMC research notes

Vallo S, Michaelis M, Gust KM, Black PC, Rothweiler F, Kvasnicka HM, Blaheta RA, Brandt MP, Wezel F, Haferkamp A, Cinatl J.
PMID: 27677700
BMC Res Notes. 2016 Sep 27;9(1):454. doi: 10.1186/s13104-016-2256-3.

BACKGROUND: Systemic chemotherapy with gemcitabine and cisplatin is standard of care for patients with metastatic urothelial bladder cancer. However, resistance formation is common after initial response. The protein Src is known as a proto-oncogene, which is overexpressed in various...

Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America.

Clinical and translational allergy

Torres MJ, Romano A, Celik G, Demoly P, Khan DA, Macy E, Park M, Blumenthal K, Aberer W, Castells M, Barbaud A, Mayorga C, Bonadonna P.
PMID: 28293415
Clin Transl Allergy. 2017 Mar 13;7:7. doi: 10.1186/s13601-017-0144-0. eCollection 2017.

Drug hypersensitivity reactions (DHRs) affect an unknown proportion of the general population, and are an important public health problem due to their potential to cause life-threatening anaphylaxis and rare severe cutaneous allergic reactions. DHR evaluations are frequently needed in...

Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients.

Central European journal of urology

Tsaur I, Thurn K, Juengel E, Oppermann E, Nelson K, Thomas C, Bartsch G, Oremek GM, Haferkamp A, Rubenwolf P, Blaheta RA.
PMID: 27729989
Cent European J Urol. 2016;69(3):247-251. doi: 10.5173/ceju.2016.820. Epub 2016 Jun 30.

INTRODUCTION: Monocyte associated transketolase-like 1 (TKTL1) as a cancer biomarker has become popular with alternative practitioners, but plays no role in conventional medicine. This investigation evaluates the potential of serum TKTL1 as a biomarker for prostate cancer.MATERIAL AND METHODS:...

Immunological deregulation in classic hodgkin lymphoma.

Mediterranean journal of hematology and infectious diseases

Romano A, Vetro C, Caocci G, Greco M, Parrinello NL, Di Raimondo F, La Nasa G.
PMID: 24959336
Mediterr J Hematol Infect Dis. 2014 Jun 01;6(1):e2014039. doi: 10.4084/MJHID.2014.039. eCollection 2014.

Classic Hodgkin Lymphoma (cHL) has a unique histology since only a few neoplastic cells are surrounded by inflammatory accessory cells that in the last years have emerged as crucial players in sustaining the course of disease. In addition, recent...

Beneficial effect of melatonin treatment on age-related insulin resistance and on the development of type 2 diabetes.

Hormone molecular biology and clinical investigation

Tresguerres JA, Cuesta S, Kireev RA, Garcia C, Acuña-Castroviejo D, Vara E.
PMID: 25436746
Horm Mol Biol Clin Investig. 2013 Dec;16(2):47-54. doi: 10.1515/hmbci-2013-0041.

Abstract This paper will review the effect of aging on glucose metabolism and insulin resistance in pancreas and in peripheral tissues and how melatonin administration could affect these parameters. In SAMP8 mice insulin levels in plasma were found to...

Valproate inhibits colon cancer growth through cell cycle modification in vivo and in vitro.

Experimental and therapeutic medicine

Strey CW, Schamell L, Oppermann E, Haferkamp A, Bechstein WO, Blaheta RA.
PMID: 22977502
Exp Ther Med. 2011 Mar;2(2):301-307. doi: 10.3892/etm.2011.202. Epub 2011 Jan 20.

Valproate (VPA) is a well-characterized histone deacetylase inhibitor with anti-neoplastic properties. We analyzed the growth blocking effects and the molecular mode of action of this compound in colorectal cancer cells in vitro and in vivo. Caco-2, SW-480, CX-1 or...

Energy Matrix of Structurally Important Side-Chain/Side-Chain Interactions in Proteins.

Journal of chemical theory and computation

Berka K, Laskowski RA, Hobza P, Vondrášek J.
PMID: 26615945
J Chem Theory Comput. 2010 Jul 13;6(7):2191-203. doi: 10.1021/ct100007y.

The interactions between amino acid side chains in proteins are generally considered to be the most important stabilizing factor controlling the precise arrangement of the polypeptide chain into a well-defined spatial structure. We used the RI-DFT-D method to calculate...

Taming chlorine azide: access to 1,2-azidochlorides from alkenes.

The Journal of organic chemistry

Valiulin RA, Mamidyala S, Finn MG.
PMID: 25719396
J Org Chem. 2015 Mar 06;80(5):2740-55. doi: 10.1021/acs.joc.5b00009. Epub 2015 Feb 26.

The in situ preparation and trapping of chlorine azide provided a versatile one-pot method for the azidochlorination of alkenes. Gaseous ClN3 generated from sodium azide, hypochlorite, and acetic acid can be explosive if isolation is attempted. Instead, we generated...

Proteomic Analysis Reveals Autophagy as Pro-Survival Pathway Elicited by Long-Term Exposure with 5-Azacitidine in High-Risk Myelodysplasia.

Frontiers in pharmacology

Romano A, Giallongo C, La Cava P, Parrinello NL, Chiechi A, Vetro C, Tibullo D, Di Raimondo F, Liotta LA, Espina V, Palumbo GA.
PMID: 28491035
Front Pharmacol. 2017 Apr 26;8:204. doi: 10.3389/fphar.2017.00204. eCollection 2017.

Azacytidine (5-AZA) is the standard first-choice treatment for high-risk myelodysplasia (MDS) patients. However, the clinical outcome for those patients who interrupt treatment or whose disease failed to respond is very poor. In order to identify the cellular pathways that...

NF-κB transcription factor role in consolidation and reconsolidation of persistent memories.

Frontiers in molecular neuroscience

de la Fuente V, Federman N, Zalcman G, Salles A, Freudenthal R, Romano A.
PMID: 26441513
Front Mol Neurosci. 2015 Sep 09;8:50. doi: 10.3389/fnmol.2015.00050. eCollection 2015.

Transcriptional regulation is an important molecular process required for long-term neural plasticity and long-term memory (LTM) formation. Thus, one main interest in molecular neuroscience in the last decades has been the identification of transcription factors that are involved in...

Understanding Multiple Sclerosis: Essentials for the Orthopaedic Surgeon.

JBJS reviews

Pidgeon TS, Borenstein T, Daniels AH, Murali J, Hayda RA.
PMID: 27490061
JBJS Rev. 2014 Jul 15;2(7). doi: 10.2106/JBJS.RVW.M.00120.

No abstract available.

Showing 1 to 12 of 1033 entries