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Showing 1 to 12 of 77 entries
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Recurrent Lower Gastrointestinal Bleeding: Ileal GIST Diagnosed by Video Capsule Endoscopy-A Case Report and Literature Review.

Case reports in gastrointestinal medicine

Ling J, Lamsen M, Coron R, Deliana D, Siddiqui S, Rangraj M, Jesmajian S.
PMID: 24027646
Case Rep Gastrointest Med. 2013;2013:285457. doi: 10.1155/2013/285457. Epub 2013 Aug 21.

Introduction. Gastrointestinal stromal tumor (GIST) in the ileum is an extremely rare cause of recurrent lower gastrointestinal bleeding (GIB). Case Report. An 89-year-old man was admitted with melana. He had extensive PMH of CAD post-CABG/AICD, AAA repair, chronic anemia,...

Onset of juvenile dermatomyositis following varicella infection in a 12-month-old child: a case report.

Journal of medical case reports

McCrea N, Al-Sabbagh A, Ahmed S, Walker D, Rangaraj S.
PMID: 24529167
J Med Case Rep. 2014 Feb 15;8:54. doi: 10.1186/1752-1947-8-54.

INTRODUCTION: Infections can act as a trigger for juvenile dermatomyositis, with a predominance of respiratory tract infections reported previously. We present the first case of juvenile dermatomyositis following varicella infection to be described in the literature.CASE PRESENTATION: A 15-month-old...

Plasma MDA and antioxidant vitamins in diabetic retinopathy.

Indian journal of clinical biochemistry : IJCB

Kumari S, Panda S, Mangaraj M, Mandal MK, Mahapatra PC.
PMID: 23105743
Indian J Clin Biochem. 2008 Apr;23(2):158-62. doi: 10.1007/s12291-008-0035-1. Epub 2008 Jun 11.

Hyperglycemia and dyslipidemia in diabetes mellitus induce increased lipid peroxidation and peroxyl radical formation, an important mechanism in genesis of microangiopathy. We took up a study on oxidative stress, measured by plasma MDA and antioxidant vitamin status in type...

Immune checkpoint inhibitors: Real-world experience from India in advanced solid cancers that have progressed on chemotherapy.

South Asian journal of cancer

Gupta VG, Rangaraju RR, Abbas W, Bajpai P, Khetrapal R.
PMID: 30766859
South Asian J Cancer. 2019 Jan-Mar;8(1):65-68. doi: 10.4103/sajc.sajc_167_18.

CONTEXT: The immune checkpoint inhibitors (ICIs) nivolumab and pembrolizumab have shown dramatic efficacy with low toxicity in international studies of advanced solid cancers. No published Indian experience with ICIs exist other than isolated case reports.AIMS: The aim of this...

Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome.

International journal of trichology

Nagakeerthana S, Rangaraj M, Karthikeyan K.
PMID: 28839390
Int J Trichology. 2017 Apr-Jun;9(2):67-69. doi: 10.4103/ijt.ijt_69_16.

Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome is a rare genetic, oculocutaneous disorder. So far, about forty patients have been reported worldwide. This disorder results from mutations in the membrane-bound transcription factor protease site 2 gene that impairs cholesterol...

'It is good to have a target in mind': qualitative views of patients and parents informing a treat to target clinical trial in juvenile-onset systemic lupus erythematosus.

Rheumatology (Oxford, England)

Smith EMD, Gorst SL, Al-Abadi E, Hawley DP, Leone V, Pilkington C, Ramanan AV, Rangaraj S, Sridhar A, Beresford MW, Young B.
PMID: 33629109
Rheumatology (Oxford). 2021 Dec 01;60(12):5630-5641. doi: 10.1093/rheumatology/keab173.

OBJECTIVE: We sought to explore patient and parental views on treatment targets, outcome measures and study designs being considered for a future JSLE treat-to-target (T2T) study.METHODS: We conducted topic-guided, semistructured interviews with JSLE patients and parents and analysed the...

Comparative efficacy, tolerability and safety of dolutegravir and efavirenz 400mg among antiretroviral therapies for first-line HIV treatment: A systematic literature review and network meta-analysis.

EClinicalMedicine

Kanters S, Vitoria M, Zoratti M, Doherty M, Penazzato M, Rangaraj A, Ford N, Thorlund K, Anis PAH, Karim ME, Mofenson L, Zash R, Calmy A, Kredo T, Bansback N.
PMID: 33294805
EClinicalMedicine. 2020 Oct 16;28:100573. doi: 10.1016/j.eclinm.2020.100573. eCollection 2020 Nov.

BACKGROUND: To inform World Health Organization (WHO) global guidelines, we updated and expanded the evidence base to assess the comparative efficacy, tolerability, and safety of first-line antiretroviral therapy (ART) regimens.METHODS: We searched Embase, Medline and CENTRAL on 28 February...

Perspective insights of repurposing the pleiotropic efficacy of statins in neurodegenerative disorders: An expository appraisal.

Current research in pharmacology and drug discovery

Bhat A, Dalvi H, Jain H, Rangaraj N, Singh SB, Srivastava S.
PMID: 34909647
Curr Res Pharmacol Drug Discov. 2020 Dec 31;2:100012. doi: 10.1016/j.crphar.2020.100012. eCollection 2021.

Neurodegenerative disorders which affects a larger population pose a great clinical challenge. These disorders impact the quality of life of an individual by damaging the neurons, which are the unit cells of the brain. Clinicians are faced with the...

Association of vitamin D and knee osteoarthritis in younger individuals.

World journal of orthopedics

Tripathy SK, Gantaguru A, Nanda SN, Velagada S, Srinivasan A, Mangaraj M.
PMID: 33134104
World J Orthop. 2020 Oct 18;11(10):418-425. doi: 10.5312/wjo.v11.i10.418. eCollection 2020 Oct 18.

BACKGROUND: The incidence of primary osteoarthritis knee is gradually increasing among young individuals. The increasing prevalence of obesity, sedentary lifestyle, sporting activity, and vitamin D deficiency (VDD) has been hypothesized for this shifting disease trend. This study was designed...

Attainment of Low Disease Activity and Remission Targets reduces the risk of severe flare and new damage in Childhood Lupus.

Rheumatology (Oxford, England)

Smith EMD, Tharmaratnam K, Al-Abadi E, Armon K, Bailey K, Brennan M, Ciurtin C, Gardner-Medwin J, Haslam KE, Hawley D, Leahy A, Leone V, Malik G, McLaren Z, Pilkington C, Ramanan AV, Rangaraj S, Ratcliffe A, Riley P, Sen E, Sridhar A, Wilkinson N, Hedrich CM, Jorgensen A, Beresford MW.
PMID: 34894234
Rheumatology (Oxford). 2021 Dec 11; doi: 10.1093/rheumatology/keab915. Epub 2021 Dec 11.

OBJECTIVES: To assess the achievability and effect of attaining low disease activity (LDA) or remission in childhood (cSLE).METHODS: Attainment of three adult-SLE derived definitions of LDA (LLDAS, LA, Toronto-LDA), and four definitions of remission (clinical-SLEDAI-defined remission on/off treatment, pBILAG-defined...

Why is Disease Penetration so Variable in Alpha-1 Antitrypsin Deficiency? The Contribution of Environmental Factors.

Chronic obstructive pulmonary diseases (Miami, Fla.)

Rangaraju M, Turner AM.
PMID: 32698254
Chronic Obstr Pulm Dis. 2020 Jul;7(3):280-289. doi: 10.15326/jcopdf.7.3.2019.0177.

Environmental influences on clinical phenotype in alpha-1 antitrypsin deficiency (AATD) include cigarette smoke, occupational exposures, airway/sputum bacteria and outdoor air pollution. This narrative review describes the impact of the major environmental exposures and summarizes their effect on clinical phenotype...

Metabolic Syndrome and Insulin Resistance in Schoolchildren From a Developing Country.

Frontiers in nutrition

Das RR, Mangaraj M, Panigrahi SK, Satapathy AK, Mahapatro S, Ray PS.
PMID: 32296710
Front Nutr. 2020 Mar 31;7:31. doi: 10.3389/fnut.2020.00031. eCollection 2020.

No abstract available.

Showing 1 to 12 of 77 entries