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Showing 1 to 12 of 149 entries
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Allotypy and structure of immunoglobulins.

Annales d'immunologie

Porter RR.
PMID: 4142570
Ann Immunol (Paris). 1974 Jan;125(1):85-91.

No abstract available.

The molecular genetics of components of complement.

Advances in immunology

Campbell RD, Carroll MC, Porter RR.
PMID: 3008521
Adv Immunol. 1986;38:203-44. doi: 10.1016/s0065-2776(08)60007-3.

Rapid progress has been made in establishing linkages and in chromosome allocation of the genes of some 9 complement components. In the MHC, C2, Factor B, and two C4 or C4 related genes have been placed in some detail...

The combining sites of antibodies.

Harvey lectures

Porter RR.
PMID: 5123651
Harvey Lect. 1971;65:157-74.

No abstract available.

Structural basis of the polymorphism of human complement components C4A and C4B: gene size, reactivity and antigenicity.

The EMBO journal

Yu CY, Belt KT, Giles CM, Campbell RD, Porter RR.
PMID: 2431902
EMBO J. 1986 Nov;5(11):2873-81.
Free PMC Article

The human complement components C4A and C4B are highly homologous proteins, but they show markedly different, class-specific, chemical reactivities. They also differ serologically in that C4A generally expresses the Rodgers (Rg) blood group antigens while C4B generally expresses the...

The biochemistry of complement.

Nature

Porter RR, Reid KB.
PMID: 703835
Nature. 1978 Oct 26;275(5682):699-704. doi: 10.1038/275699a0.

Current biochemical studies of the complement system are illustrated by description of the activation of complement by the classical pathway after interaction with antibody aggregates. This is described in terms of the structures of the components involved, their assembly...

Complement polymorphism, the major histocompatibility complex and associated diseases: a speculation.

Molecular biology & medicine

Porter RR.
PMID: 6679872
Mol Biol Med. 1983 Jul;1(1):161-8.

Genes in the major histocompatibility complex code for three major groups of glycoproteins, now referred to as classes I, II, and III. Susceptibility to some autoimmune diseases and to systemic lupus erythematosus is associated with the presence of particular...

Subunit composition and structure of subcomponent C1q of the first component of human complement.

The Biochemical journal

Reid KB, Porter RR.
PMID: 938474
Biochem J. 1976 Apr 01;155(1):19-23. doi: 10.1042/bj1550019.
Free PMC Article

1. Unreduced human subcomponent C1q was shown by electrophoresis on polyacrylamide gels run in the presence of sodium dodecyl sulphate to be composed of two types of non-covalently linked subunits of apparent mol.wts. 69 000 and 54 000. The...

The assembly of early components of complement on antibody-antigen aggregates and on antibody-coated erythrocytes.

The Biochemical journal

Goers JW, Porter RR.
PMID: 743217
Biochem J. 1978 Nov 01;175(2):675-84. doi: 10.1042/bj1750675.
Free PMC Article

Radioimmune assays were developed to assay the binding of complement components C1q, C1s and C4 to antibody aggregates and to cell-bound antibody. The binding of the components was compared with the haemolytic activity and with the capacity to form...

The activation of complement components by aggregates of antibodies and their fragments.

Molecular immunology

Dodds AW, Porter RR.
PMID: 542202
Mol Immunol. 1979 Dec;16(12):1059-62. doi: 10.1016/0161-5890(79)90039-7.

No abstract available.

A structural model for the location of the Rodgers and the Chido antigenic determinants and their correlation with the human complement component C4A/C4B isotypes.

Immunogenetics

Yu CY, Campbell RD, Porter RR.
PMID: 2453459
Immunogenetics. 1988;27(6):399-405. doi: 10.1007/BF00364425.

No abstract available.

Characterization of a plasmin-digest fragment of rabbit immunoglobulin gamma that binds antigen and complement.

The Biochemical journal

Colomb M, Porter RR.
PMID: 239679
Biochem J. 1975 Feb;145(2):177-83. doi: 10.1042/bj1450177.
Free PMC Article

Rabbit immunoglobulin gamma (IgG) was digested with plasmin after being left for 15 min at pH2.5, 30 degrees C followed by a rapid increase in the pH to 7. The fragment antigen and complement binding (Facb) was isolated and...

The structure of antibodies. The basic pattern of the principal class of molecules that neutralize antigens (foreign substances in the body) is four cross-linked chains. This pattern is modified so that antibodies can fit different antigens.

Scientific American

Porter RR.
PMID: 4169321
Sci Am. 1967 Oct;217(4):81-7 passim.

No abstract available.

Showing 1 to 12 of 149 entries