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Showing 1 to 12 of 33 entries
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Small Fiber Neuropathy in Patients With Latent Autoimmune Diabetes in Adults.

Diabetes care

Alam U, Asghar O, Petropoulos IN, Jeziorska M, Fadavi H, Ponirakis G, Marshall A, Tavakoli M, Boulton AJ, Efron N, Malik RA.
PMID: 26106229
Diabetes Care. 2015 Jul;38(7):e102-3. doi: 10.2337/dc14-2354.

No abstract available.

Metformin Use Is Not Associated With B.

Frontiers in endocrinology

Elhadd T, Ponirakis G, Dabbous Z, Siddique M, Chinnaiyan S, Malik RA.
PMID: 29887831
Front Endocrinol (Lausanne). 2018 May 25;9:248. doi: 10.3389/fendo.2018.00248. eCollection 2018.

BACKGROUND: Metformin may lead to BAIMS: Determine whether Metformin intake is associated with BMETHODS: Patients with type 2 diabetes mellitus (T2DM) (RESULTS: Comparing Metformin to non-Metformin users there were no differences in BCONCLUSION: Serum B

Addition or removal of guideline directed medical therapy in ambulatory patients with heart failure with reduced ejection fraction relative to change in symptom severity: An analysis from the PINNACLE (Practice Innovation and Clinical Excellence) Registry®.

International journal of cardiology

Ibrahim NE, Song Y, Cannon CP, Doros G, Trebnick A, Russo P, Ponirakis A, Alexanian C, Januzzi JL.
PMID: 29407094
Int J Cardiol. 2018 Mar 01;254:222-223. doi: 10.1016/j.ijcard.2017.10.096. Epub 2018 Jan 28.

No abstract available.

Retraction notice to Addition or removal of guideline directed medical therapy in ambulatory patients with heart failure with reduced ejection fraction relative to change in symptom severity: An analysis from the PINNACLE (Practice Innovation and Clinical Excellence) Registry® [International Journal of Cardiology 254 (2018) 222-223].

International journal of cardiology

Ibrahim NE, Song Y, Cannon CP, Doros G, Trebnick A, Russo P, Ponirakis A, Alexanian C, Januzzi JL.
PMID: 29752128
Int J Cardiol. 2018 Mar 01;254:R1. doi: 10.1016/j.ijcard.2018.05.008.

No abstract available.

Painful diabetic neuropathy is associated with increased nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control.

Journal of diabetes investigation

Ponirakis G, Abdul-Ghani MA, Jayyousi A, Zirie MA, Qazi M, Almuhannadi H, Petropoulos IN, Khan A, Gad H, Migahid O, Megahed A, Al-Mohannadi S, AlMarri F, Al-Khayat F, Mahfoud Z, Al Hamad H, Ramadan M, DeFronzo R, Malik RA.
PMID: 33714226
J Diabetes Investig. 2021 Sep;12(9):1642-1650. doi: 10.1111/jdi.13544. Epub 2021 May 03.

AIMS/INTRODUCTION: Painful diabetic peripheral neuropathy (pDPN) is associated with small nerve fiber degeneration and regeneration. This study investigated whether the presence of pDPN might influence nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control.MATERIALS AND METHODS:...

Temporal and spatial lags between wind, coastal upwelling, and blue whale occurrence.

Scientific reports

Barlow DR, Klinck H, Ponirakis D, Garvey C, Torres LG.
PMID: 33767285
Sci Rep. 2021 Mar 25;11(1):6915. doi: 10.1038/s41598-021-86403-y.

Understanding relationships between physical drivers and biological response is central to advancing ecological knowledge. Wind is the physical forcing mechanism in coastal upwelling systems, however lags between wind input and biological responses are seldom quantified for marine predators. Lags...

Diagnosing Diabetic Neuropathy: Something Old, Something New.

Diabetes & metabolism journal

Petropoulos IN, Ponirakis G, Khan A, Almuhannadi H, Gad H, Malik RA.
PMID: 30136449
Diabetes Metab J. 2018 Aug;42(4):255-269. doi: 10.4093/dmj.2018.0056.

There are potentially many ways of assessing diabetic peripheral neuropathy (DPN). However, they do not fulfill U.S. Food and Drug Administration (FDA) requirements in relation to their capacity to assess therapeutic benefit in clinical trials of DPN. Over the...

Corneal confocal microscopy identifies a reduction in corneal keratocyte density and sub-basal nerves in children with type 1 diabetes mellitus.

The British journal of ophthalmology

Gad H, Al-Jarrah B, Saraswathi S, Mohamed S, Kalteniece A, Petropoulos IN, Khan A, Ponirakis G, Singh P, Khodor SA, Elawad M, Almasri W, Hendaus MA, Akobeng AK, Hussain K, Malik RA.
PMID: 33931390
Br J Ophthalmol. 2021 Apr 30; doi: 10.1136/bjophthalmol-2021-319057. Epub 2021 Apr 30.

PURPOSE: To assess whether alterations in stromal keratocyte density are related to loss of corneal nerve fibres in children with type 1 diabetes mellitus (T1DM).METHODS: Twenty participants with T1DM and 20 age-matched healthy controls underwent corneal confocal microscopy. Corneal...

Vitamin D deficiency is associated with painful diabetic neuropathy.

Diabetes/metabolism research and reviews

Alam U, Petropoulos IN, Ponirakis G, Ferdousi M, Asghar O, Jeziorska M, Marshall A, Boulton AJM, Efron N, Malik RA.
PMID: 32506740
Diabetes Metab Res Rev. 2021 Jan;37(1):e3361. doi: 10.1002/dmrr.3361. Epub 2020 Jul 09.

BACKGROUND: The aetiology of painful diabetic neuropathy is unclear. We have evaluated vitamin D levels in diabetic patients with and without painful neuropathy.METHODS: Forty-three patients with type 1 diabetes and painless (DPN) (n = 20) or painful (PDN) (n...

No evidence of improvement in neuropathy after renal transplantation in patients with end stage kidney disease.

Journal of the peripheral nervous system : JPNS

Ferdousi M, Azmi S, Kalteniece A, Khan SU, Petropoulos IN, Ponirakis G, Alam U, Asghar O, Marshall A, Soran H, Boulton AJM, Augustine T, Malik RA.
PMID: 34085731
J Peripher Nerv Syst. 2021 Sep;26(3):269-275. doi: 10.1111/jns.12456. Epub 2021 Jun 10.

To assess the impact of renal transplantation on peripheral nerve damage in patients with chronic kidney disease (CKD). Fifteen patients with CKD (eGFR

Subclinical Corneal Nerve Fiber Damage and Immune Cell Activation in Systemic Lupus Erythematosus: A Corneal Confocal Microscopy Study.

Translational vision science & technology

Bitirgen G, Kucuk A, Ergun MC, Baloglu R, Gharib MH, Al Emadi S, Ponirakis G, Malik RA.
PMID: 34905000
Transl Vis Sci Technol. 2021 Dec 01;10(14):10. doi: 10.1167/tvst.10.14.10.

PURPOSE: The purpose of this study was to evaluate the utility of corneal confocal microscopy (CCM) in identifying small nerve fiber damage and immune cell activation in patients with systemic lupus erythematosus (SLE).METHODS: This cross-sectional comparative study included 39...

Corneal confocal microscopy demonstrates axonal loss in different courses of multiple sclerosis.

Scientific reports

Petropoulos IN, Fitzgerald KC, Oakley J, Ponirakis G, Khan A, Gad H, George P, Deleu D, Canibano BG, Akhtar N, Shuaib A, Own A, Malik T, Russakoff DB, Mankowski JL, Misra SL, McGhee CNJ, Calabresi P, Saidha S, Kamran S, Malik RA.
PMID: 34737384
Sci Rep. 2021 Nov 04;11(1):21688. doi: 10.1038/s41598-021-01226-1.

Axonal loss is the main determinant of disease progression in multiple sclerosis (MS). This study aimed to assess the utility of corneal confocal microscopy (CCM) in detecting corneal axonal loss in different courses of MS. The results were confirmed...

Showing 1 to 12 of 33 entries