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Showing 1 to 12 of 83 entries
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Treatment of wounds colonized by multidrug resistant organisms in immune-compromised patients: a retrospective case series.

Patient safety in surgery

Pignatti M, Gerunda GE, Rompianesi G, De Ruvo N, Di Benedetto F, Codeluppi M, Bonucchi D, Pacchioni L, Loschi P, Malaventura C, De Santis G.
PMID: 24139428
Patient Saf Surg. 2013 Sep 03;7(1):28. doi: 10.1186/1754-9493-7-28.

BACKGROUND: Immune-compromised patients incur a high risk of surgical wound dehiscence and colonization by multidrug resistant organisms. Common treatment has been debridement and spontaneous secondary healing.We report on the results obtained in nine such patients whose wounds were treated...

Two stage hip revision in periprosthetic infection: results of 41 cases.

The open orthopaedics journal

Pignatti G, Nitta S, Rani N, Dallari D, Sabbioni G, Stagni C, Giunti A.
PMID: 20721319
Open Orthop J. 2010 Jun 11;4:193-200. doi: 10.2174/1874325001004010193.

BACKGROUND: two-stage revision is considered the best treatment approach for the eradication of chronic joint infection. We report the outcome of 41 consecutive patients with infected hip prostheses, treated between 2000 and 2005, with two-stage revision using an antibiotic-loaded...

Joint Instability After Anatomic Reconstruction of Severe, Chronic Slipped Capital Femoral Epiphysis: A Report of 3 Cases, with High Femoral Anteversion in 1 and Adaptive Acetabular Roof Deformation in 3.

JBJS case connector

Ganz R, Aprato A, Mazziotta G, Pignatti G.
PMID: 29252682
JBJS Case Connect. 2016 Apr-Jun;6(2):e50. doi: 10.2106/JBJS.CC.15.00149.

CASES: Joint instability after slipped capital femoral epiphysis (SCFE) reorientation through the physis has been attributed to a combination of capsulotomy and chondrolabral rim damage. We report on 3 hips with severe SCFE with closed physes, in which anatomic...

European Medicines Agency review of ixazomib (Ninlaro) for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

ESMO open

Tzogani K, Florez B, Markey G, Caleno M, Olimpieri OM, Melchiorri D, Hovgaard DJ, Sarac SB, Penttilä K, Lapveteläinen T, Salmonson T, Bergh J, Gisselbrecht C, Pignatti F.
PMID: 31555488
ESMO Open. 2019 Sep 08;4(5):e000570. doi: 10.1136/esmoopen-2019-000570. eCollection 2019.

On 21 November 2016, the European Commission issued a marketing authorisation valid throughout the European Union for ixazomib in combination with lenalidomide and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one...

Antibiotic drug not always the culprit: Allergy to a homoeopathic product.

International journal of clinical practice

Marraccini P, Lari SA, Conforti E, Pignatti P.
PMID: 32168405
Int J Clin Pract. 2020 Jul;74(7):e13500. doi: 10.1111/ijcp.13500.

No abstract available.

The European Medicines Agency Review of Luspatercept for the Treatment of Adult Patients With Transfusion-dependent Anemia Caused by Low-risk Myelodysplastic Syndromes With Ring Sideroblasts or Beta-thalassemia.

HemaSphere

Delgado J, Voltz C, Stain M, Balkowiec-Iskra E, Mueller B, Wernsperger J, Malinowska I, Gisselbrecht C, Enzmann H, Pignatti F.
PMID: 34291195
Hemasphere. 2021 Jul 19;5(8):e616. doi: 10.1097/HS9.0000000000000616. eCollection 2021 Aug.

Luspatercept is a recombinant fusion protein that selectively binds to ligands belonging to the transforming growth factor-beta superfamily, resulting in erythroid maturation and differentiation. On June 25, 2020, a marketing authorization valid through the European Union (EU) was issued...

Non-anesthesiologist sedation (NAS): The Italian retrotopia needs to be overcome.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Manno M, Biancheri P, Pignatti A, Becchi E, Gazzi M, Soriani P.
PMID: 34162510
Dig Liver Dis. 2021 Nov;53(11):1513-1514. doi: 10.1016/j.dld.2021.05.036. Epub 2021 Jun 20.

No abstract available.

Mode of birth in women with low-lying placenta: protocol for a prospective multicentre 1:3 matched case-control study in Italy (the MODEL-PLACENTA study).

BMJ open

Ornaghi S, Colciago E, Vaglio Tessitore I, Abbamondi A, Antolini L, Locatelli A, Inversetti A, Pintucci A, Cetin I, Bracco B, Fabbri E, Sala V, Meroni M, Volpe G, Benedetti S, Bulfoni C, Marconi A, Lagrasta F, Paolini CL, Mazza E, Candiani M, Valsecchi L, Smid M, Pasi F, Pozzoni M, Castoldi M, Vignali M, Dal Molin G, Guarano A, Pellegrino A, Callegari C, Betti M, Lazzarin S, Prefumo F, Zanardini C, Parolin V, Catalano A, Barbolini E, Antonazzo P, Pignatti L, Tintoni M, Spelzini F, Martinelli A, Facchinetti F, Chiossi G, Vergani P.
PMID: 34873004
BMJ Open. 2021 Dec 06;11(12):e052510. doi: 10.1136/bmjopen-2021-052510.

INTRODUCTION: The term placenta praevia defines a placenta that lies over the internal os, whereas the term low-lying placenta identifies a placenta that is partially implanted in the lower uterine segment with the inferior placental edge located at 1-20...

A snapshot of exhaled nitric oxide and asthma characteristics: experience from high to low income countries.

Pulmonology

Pignatti P, Visca D, Loukides S, Märtson AG, Alffenaar JC, Migliori GB, Spanevello A.
PMID: 33358001
Pulmonology. 2022 Jan-Feb;28(1):44-58. doi: 10.1016/j.pulmoe.2020.10.016. Epub 2020 Dec 21.

Nitric oxide is a gas produced in the airways of asthmatic subjects and related to T2 inflammation. It can be measured as fractional nitric oxide (FeNO) in the exhaled air and used as a non-invasive, easy to evaluate, rapid...

Extension of Indication for Authorised Oncology Products in the European Union: A Joint Effort of Multiple Stakeholders.

Frontiers in medicine

Mulder J, Verjans R, Verbaanderd C, Pean E, Weemers J, Leufkens HGM, Pignatti F, de Boer A, Voest EE, Stoyanova-Beninska VV, Pasmooij AMG.
PMID: 34957158
Front Med (Lausanne). 2021 Dec 09;8:790782. doi: 10.3389/fmed.2021.790782. eCollection 2021.

After marketing authorisation, the development of a medicinal product often continues with studies investigating new therapeutic indications. Positive results can potentially lead to changes to the terms of the marketing authorisation, such as an extension of therapeutic indication(s). These...

Extension of Indication for Authorised Oncology Products in the European Union: A Joint Effort of Multiple Stakeholders.

Frontiers in medicine

Mulder J, Verjans R, Verbaanderd C, Pean E, Weemers J, Leufkens HGM, Pignatti F, de Boer A, Voest EE, Stoyanova-Beninska VV, Pasmooij AMG.
PMID: 34957158
Front Med (Lausanne). 2021 Dec 09;8:790782. doi: 10.3389/fmed.2021.790782. eCollection 2021.

After marketing authorisation, the development of a medicinal product often continues with studies investigating new therapeutic indications. Positive results can potentially lead to changes to the terms of the marketing authorisation, such as an extension of therapeutic indication(s). These...

Nutrients and Pathways that Regulate Health Span and Life Span.

Geriatrics (Basel, Switzerland)

Pignatti C, D'Adamo S, Stefanelli C, Flamigni F, Cetrullo S.
PMID: 33228041
Geriatrics (Basel). 2020 Nov 19;5(4). doi: 10.3390/geriatrics5040095.

Both life span and health span are influenced by genetic, environmental and lifestyle factors. With the genetic influence on human life span estimated to be about 20-25%, epigenetic changes play an important role in modulating individual health status and...

Showing 1 to 12 of 83 entries