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Showing 1 to 12 of 31 entries
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Secondary Data Analytics of Aquaporin Expression Levels in Glioblastoma Stem-Like Cells.

Cancer informatics

Isokpehi RD, Wollenberg Valero KC, Graham BE, Pacurari M, Sims JN, Udensi UK, Ndebele K.
PMID: 26279619
Cancer Inform. 2015 Jul 30;14:95-103. doi: 10.4137/CIN.S22058. eCollection 2015.

Glioblastoma is the most common brain tumor in adults in which recurrence has been attributed to the presence of cancer stem cells in a hypoxic microenvironment. On the basis of tumor formation in vivo and growth type in vitro,...

The Renin-Angiotensin-aldosterone system in vascular inflammation and remodeling.

International journal of inflammation

Pacurari M, Kafoury R, Tchounwou PB, Ndebele K.
PMID: 24804145
Int J Inflam. 2014;2014:689360. doi: 10.1155/2014/689360. Epub 2014 Apr 06.

The RAAS through its physiological effectors plays a key role in promoting and maintaining inflammation. Inflammation is an important mechanism in the development and progression of CVD such as hypertension and atherosclerosis. In addition to its main role in...

Retinoids and citral modulated cell viability, metabolic stability, cell cycle progression and distribution in the a549 lung carcinoma cell line - biomed 2010.

Biomedical sciences instrumentation

Farah IO, Trimble Q, Ndebele K, Mawson A.
PMID: 20467116
Biomed Sci Instrum. 2010;46:410-21.

Lung cancer is the second leading deadly cancer in United States. In 2007, the United States reported 213,380 new lung cancer diagnoses and 160,390 deaths caused by lung cancer. Retinoic acid and retinyl esters are the oxidized and storage...

Open data sharing and the Global South-Who benefits?.

Science (New York, N.Y.)

Serwadda D, Ndebele P, Grabowski MK, Bajunirwe F, Wanyenze RK.
PMID: 29439233
Science. 2018 Feb 09;359(6376):642-643. doi: 10.1126/science.aap8395.

No abstract available.

Evaluation of Arsenic Trioxide Potential for Lung Cancer Treatment: Assessment of Apoptotic Mechanisms and Oxidative Damage.

Journal of cancer science & therapy

Walker AM, Stevens JJ, Ndebele K, Tchounwou PB.
PMID: 27158419
J Cancer Sci Ther. 2016 Jan;8(1):1-9. doi: 10.4172/1948-5956.1000379. Epub 2015 Dec 18.

BACKGROUND: Lung cancer is one of the most lethal and common cancers in the world, causing up to 3 million deaths annually. The chemotherapeutic drugs that have been used in treating lung cancer include cisplatin-pemetrexed, cisplastin-gencitabinoe, carboplatin-paclitaxel and crizotinib....

Facts about the General Medical Care of Adults with Congenital Heart Defects: Experience of a Tertiary Care Center.

Journal of clinical medicine

Seidel L, Nebel K, Achenbach S, Bauer U, Ewert P, Freilinger S, Gundlach U, Kaemmerer H, Nagdyman N, Oberhoffer R, Pieper L, Reinhard W, Sanftenberg L, Schelling J, Weyand M, Neidenbach R.
PMID: 32580342
J Clin Med. 2020 Jun 22;9(6). doi: 10.3390/jcm9061943.

No abstract available.

Higher-order dispersion and nonlinear effects of optical fibers under septic self-steepening and self-frequency shift.

Physical review. E

Ndebele KK, Tabi CB, Tiofack CGL, Kofané TC.
PMID: 34781579
Phys Rev E. 2021 Oct;104(4):044208. doi: 10.1103/PhysRevE.104.044208.

We investigate the modulational instability (MI) of a continuous wave (cw) under the combined effects of higher-order dispersions, self steepening and self-frequency shift, cubic, quintic, and septic nonlinearities. Using Maxwell's theory, an extended nonlinear Schrödinger equation is derived. The...

Understanding Ethical, Legal and Societal Issues (ELSIs) in Human Biobanking and Genomics for Research and Healthcare in Zimbabwe: The Genomics Inheritance Law Ethics and Society GILES initiative.

AAS open research

Matimba A, Chimatira A, Kuguyo O, January J, Mupambireyi Z, Marimbe-Dube B, Chikwasha V, Nyati-Jokomo Z, Muteti S, Mangezvo P, Kangwende A, Chingono A, Chidzonga M, Gandari J, Hakim J, Nathoo K, Samkange C, Mangezi W, Lee S, Gwanzura L, Cho M, Ndebele P.
PMID: 32382699
AAS Open Res. 2019 Jan 08;2:1. doi: 10.12688/aasopenres.12917.1. eCollection 2019.

Biobanks and human genomics applications are key for understanding health, disease and heredity in Africa and globally. Growing interest in these technologies calls for strengthening relevant legal, ethical and policy systems to address knowledge disparities and ensure protection of...

A case report of complete appendiceal duplication on the normal site of a single caecum: A new variant?.

International journal of surgery case reports

Ngulube A, Ntoto COM, Matsika D, Ndebele W, Dube NS, Gapu P.
PMID: 32862109
Int J Surg Case Rep. 2020;74:168-172. doi: 10.1016/j.ijscr.2020.08.013. Epub 2020 Aug 20.

INTRODUCTION: Duplicated appendix is an uncommon entity, typically discovered as an incidental finding during surgery for appendicitis or other abdominal pathologies. It may be associated with other congenital malformations. We report a case of a male neonate incidentally discovered...

Reactivity and structural evolution of urchin-like Co nanostructures under controlled environments.

Journal of microscopy

Dembele K, Moldovan S, Hirlimann C, Harmel J, Soulantica K, Serp P, Chaudret B, Gay AS, Maury S, Berliet A, Fecant A, Ersen O.
PMID: 29064561
J Microsc. 2018 Feb;269(2):168-176. doi: 10.1111/jmi.12656. Epub 2017 Oct 24.

In situ transmission electron microscopy (TEM) of samples in a controlled gas environment allows for the real time study of the dynamical changes in nanomaterials at high temperatures and pressures up to the ambient pressure (10

COVID-19 vaccine mandate for healthcare workers in the United States: a social justice policy.

Expert review of vaccines

Hagan K, Forman R, Mossialos E, Ndebele P, Hyder AA, Nasir K.
PMID: 34709969
Expert Rev Vaccines. 2022 Jan;21(1):37-45. doi: 10.1080/14760584.2022.1999811. Epub 2021 Nov 16.

INTRODUCTION: Vaccination is the most effective strategy to mitigating COVID-19 and restoring societal function. As the pandemic evolves with no certainty of a herd immunity threshold, universal vaccination of at-risk populations is desirable. However, vaccine hesitancy threatens the return...

Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria.

Gates open research

Thizy D, Pare Toe L, Mbogo C, Matoke-Muhia D, Alibu VP, Barnhill-Dilling SK, Chantler T, Chongwe G, Delborne J, Kapiriri L, Nassonko Kavuma E, Koloi-Keaikitse S, Kormos A, Littler K, Lwetoijera D, Vargas de Moraes R, Mumba N, Mutengu L, Mwichuli S, Nabukenya SE, Nakigudde J, Ndebele P, Ngara C, Ochomo E, Odiwuor Ondiek S, Rivera S, Roberts AJ, Sambakunsi R, Saxena A, Sykes N, Tarimo BB, Tiffin N, Tountas KH.
PMID: 33884362
Gates Open Res. 2021 Jan 29;5:19. doi: 10.12688/gatesopenres.13221.1. eCollection 2021.

Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many literature sources and guidance point to the inadequacy of individual informed consent for any genetically modified mosquito release, including...

Showing 1 to 12 of 31 entries