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Hyperproinsulinaemia in patients with myotonic dystrophy.


Krentz AJ, Clark PM, Cox L, Williams AC, Nattrass M.
PMID: 1478370
Diabetologia. 1992 Dec;35(12):1170-2. doi: 10.1007/BF00401372.

Hyperinsulinaemia is a reported feature of the inherited multisystem disorder myotonic dystrophy. This phenomenon has been attributed to a compensatory beta cell response to tissue insulin resistance. In this study, circulating concentrations of insulin, proinsulin, and split proinsulin molecules...

Hyperlactatemia in diabetics with retinopathy during combined sulphonylurea and phenformin therapy.

Diabete & metabolisme

Nattrass M, Arthur MJ, Smythe P, McGill JI, Todd PG, Alberti KG.
PMID: 668976
Diabete Metab. 1978 Mar;4(1):1-4.

Blood lactate concentration has been measured at intervals over a twelve hour period in four maturity-onset diabetics with retinopathy treated by sulphonylurea and phenformin therapy. Despite moderately good control of blood glucose, all four patients had markedly elevated concentrations...

Metabolic profiles in patients with insulinoma.

Clinical endocrinology

Hale PJ, Nattrass M.
PMID: 2550166
Clin Endocrinol (Oxf). 1989 Jan;30(1):29-38. doi: 10.1111/j.1365-2265.1989.tb03724.x.

Twelve-hour metabolic profiles have been measured in six patients with insulinoma and results compared with normal subjects of similar age and weight. Fasting blood glucose was lower (mean +/- SEM 2.9 +/- 0.3 mmol/l vs 5.0 +/- 0.2 mmol/l)...

Impaired glucose tolerance in obesity is associated with insensitivity to insulin in multiple aspects of metabolism as assessed by a low dose incremental insulin infusion technique.

Diabetic medicine : a journal of the British Diabetic Association

Robertson DA, Singh BM, Nattrass M.
PMID: 1838062
Diabet Med. 1991 Oct;8(8):718-25. doi: 10.1111/j.1464-5491.1991.tb01690.x.

To determine whether Impaired Glucose Tolerance gives rise to additional defects in insulin action in lipid and ketone metabolism, thirty-two obese subjects were studied by low-dose incremental insulin infusion. Sixteen had Impaired Glucose Tolerance and 16 had normal glucose...

Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity-onset diabetics.


Nattrass M, Todd PG, Hinks L, Lloyd B, Alberti KG.
PMID: 404205
Diabetologia. 1977 Apr;13(2):145-52. doi: 10.1007/BF00745143.

Twelve hour metabolic rhythms have been performed on six maturity-onset diabetic subjects during successive periods of therapy with phenformin, metformin, and glibenclamide. Moderate control of blood glucose concentration was achieved with phenformin and metformin, the lowest concentrations being found...

The short-term effect of nicotinic acid on intermediary metabolism in insulin-dependent diabetes mellitus.

Annals of clinical biochemistry

Hale PJ, Nattrass M.
PMID: 2024932
Ann Clin Biochem. 1991 Jan;28:39-43. doi: 10.1177/000456329102800106.

The short-term effect of the lipid lowering agent nicotinic acid on circulating concentrations of insulin, glucose, lactate, pyruvate, non-esterified fatty acids (NEFA), glycerol, total ketone bodies and triglycerides was examined in six insulin-dependent diabetic patients. On two occasions a...

Focus on urinalysis. Part 2.

Nursing times

Jelphs K, Nattrass M.
PMID: 3636841
Nurs Times. 1986 May 14-20;82(20):suppl 1-6.

No abstract available.

Abnormalities of glucose homeostasis in diabetes.

The Proceedings of the Nutrition Society

Nattrass M.
PMID: 1809966
Proc Nutr Soc. 1991 Dec;50(3):577-81. doi: 10.1079/pns19910071.

No abstract available.

Basal intermediary metabolism in impaired glucose tolerance and morbid obesity.

Diabetes research (Edinburgh, Scotland)

Krentz AJ, Singh BM, Hale PJ, Robertson DA, Nattrass M.
PMID: 1345002
Diabetes Res. 1992;20(3):51-60.

The effects of impaired glucose tolerance and obesity, in isolation and in combination, on basal (postabsorptive) intermediary metabolism were examined in four groups of subjects (n = 10 for each) matched for age and gender: Group 1: Non-obese healthy...

Metabolic effects of aldose reductase inhibition in diabetic man.

Diabetes research (Edinburgh, Scotland)

Krentz AJ, Ellis SH, Hardman M, Nattrass M.
PMID: 1468186
Diabetes Res. 1992 Jan;19(1):41-8.

The metabolic effects of 52 weeks treatment with the aldose reductase inhibitor ponalrestat were examined in 32 diabetic patients (16 insulin treated) in a randomized, double-blind, placebo-controlled clinical trial. Twelve hour metabolic profiles were performed on two separate occasions...

Control of diabetes mellitus in shift workers.

British journal of industrial medicine

Poole CJ, Wright AD, Nattrass M.
PMID: 1637712
Br J Ind Med. 1992 Jul;49(7):513-5. doi: 10.1136/oem.49.7.513.
Free PMC Article

OBJECTIVE: To determine whether the control of diabetes is different in insulin treated diabetic subjects who work shifts compared with those who do not work shifts and whether control is related to the type of shift worked.DESIGN: Prospective controlled...

Diuretics and hyperkalaemia in diabetic ketoacidosis.

Diabetic medicine : a journal of the British Diabetic Association

Olczak SA, Fitzgerald MG, Nattrass M, Wright AD.
PMID: 2964331
Diabet Med. 1988 Jan;5(1):68-9. doi: 10.1111/j.1464-5491.1988.tb00944.x.

Diabetic ketoacidosis (DKA) often presents with hyperkalaemia. We investigated whether it was more likely in patients taking potassium-retaining diuretics. A retrospective survey of all patients (552 cases) presenting in DKA between 1974 and 1984 was undertaken. Initial biochemical data...

Showing 1 to 12 of 118 entries