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Showing 1 to 12 of 157 entries
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Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks.

Cancers

Jones NR, Ashmore JH, Lee SY, Richie JP, Lazarus P, Muscat JE.
PMID: 26690219
Cancers (Basel). 2015 Dec 09;7(4):2386-96. doi: 10.3390/cancers7040898.

BACKGROUND: Polymorphisms in the hemochromatosis (HFE) gene are associated with excessive iron absorption from the diet, and pro-oxidant effects of iron accumulation are thought to be a risk factor for several types of cancer.METHODS: The C282Y (rs1800562) and H63D...

Dissociation of the effects of amphetamine and quinpirole on dopamine release in the nucleus accumbens following behavioural sensitization: an ex vivo voltammetric study.

Behavioural pharmacology

Muscat R, Patel J, Trout SJ, Wieczorek W, Kruk ZL.
PMID: 11224210
Behav Pharmacol. 1993;4(4):411-418.

Behavioural sensitization to the locomotor stimulant effect of (+)-amphetamine or quinpirole was induced in rats by intermittent drug administration. Once established, endogenous dopamine release (DA) was measured in slices containing nucleus accumbens using fast cyclic voltammetry. DA release induced...

Time-dependent and schedule-dependent effects of dopamine receptor blockade.

Behavioural pharmacology

Willner P, Phillips G, Sampson D, Muscat R.
PMID: 11175400
Behav Pharmacol. 1989;1(2):169-176.

Rats were trained on one of two multiple random-interval schedules of reinforcement, which contained both ascending and descending reinforcement density sequences. The design of the schedules made it possible to determine whether performance changes in a particular component depended...

Letter to the editor.

Science (New York, N.Y.)

Muskat M.
PMID: 17792533
Science. 1975 Aug 29;189(4204):707. doi: 10.1126/science.189.4204.707-b.

Morris Muskat (Letters, 6 June, p. 973) refers to "the only certain new net [oil] supplies we can count on by 1985 ... when the Alaskan pipeline is operating." The amount cited should have been "1 to 2 million...

Latters to the editor.

Science (New York, N.Y.)

Muskat M.
PMID: 17759665
Science. 1975 Jun 06;188(4192):973-4. doi: 10.1126/science.188.4192.973-a.

No abstract available.

The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?.

Nuclear receptor signaling

Ramakrishnan SN, Muscat GE.
PMID: 16741567
Nucl Recept Signal. 2006;4:e009. doi: 10.1621/nrs.04009. Epub 2006 Apr 28.

Nuclear hormone receptors (NRs) function as ligand dependent DNA binding proteins that translate physiological/nutritional signals into gene regulation. Dysfunctional NR signaling leads to many disorders in reproduction, inflammation, and metabolism. The opportunity to identify novel regulatory pathways in the...

[Prophylactic cranial irradiation in patients with extensive disease caused by small-cell lung cancer responsive to chemotherapy: fewer symptomatic brain metastases and improved survival].

Nederlands tijdschrift voor geneeskunde

Slotman BJ, Faivre-Finn C, Kramer GW, Rankin E, Snee M, Hatton M, Postmus PE, Collette L, Musat E, Senan S.
PMID: 18549175
Ned Tijdschr Geneeskd. 2008 Apr 26;152(17):1000-4.

OBJECTIVE: To determine the effect of prophylactic cranial irradiation (PCI) in patients with extensive-disease small-cell lung cancer (ED-SCLC) who responded to chemotherapy.DESIGN: Randomised, controlled clinical trial; phase III study (EORTC nr 08993-22993; www.clinicaltrials.gov, nr NCT00016211).METHOD: Patients aged 18-75 years...

Treatment planning study of the 3D dosimetric differences between Co-60 and Ir-192 sources in high dose rate (HDR) brachytherapy for cervix cancer.

Journal of contemporary brachytherapy

Palmer A, Hayman O, Muscat S.
PMID: 23346140
J Contemp Brachytherapy. 2012 Mar;4(1):52-9. doi: 10.5114/jcb.2012.27952. Epub 2012 Mar 30.

PURPOSE: To evaluate whether Co-60 is equivalent to Ir-192 for HDR cervical brachytherapy, through 3D-DVH dose comparisons in standard and optimised plans. Previous studies have only considered 2D dosimetry, point dose comparisons or identical loading. Typical treatment times and...

P53 protein overexpression in lung adenocarcinomas in non-smokers.

Oncology reports

Muscat J, Citron M, Wang C, White A, Lazarus P.
PMID: 21590150
Oncol Rep. 1997 Jul-Aug;4(4):825-7. doi: 10.3892/or.4.4.825.

Greater than 55% of all lung cancers contain mutations in the p53 tumor suppressor gene, and the frequency of p53 mutations has been directly correlated with the use of tobacco and the smoking of cigarettes. To determine if environmental...

Effects of amphetamine and pimozide on reinforcement and motor parameters in variable-interval performance.

Journal of psychopharmacology (Oxford, England)

Willner P, Towell A, Muscat R.
PMID: 22158977
J Psychopharmacol. 1987 Jan;1(3):140-53. doi: 10.1177/026988118700100302.

The effects of amphetamine and pimozide were studied in rats performing on variable-interval (VI) schedules of reinforcement. In experiment 1, a five-component multiple VI schedule was used; in experiments 2 and 3, two VI schedules were presented on alternate...

Knowing You, Knowing Me (KYKM): an interactive game to address positive mother-daughter communication and relationships.

Frontiers in psychology

Katsikitis M, Jones C, Muscat M, Crawford K.
PMID: 25071682
Front Psychol. 2014 Jul 11;5:721. doi: 10.3389/fpsyg.2014.00721. eCollection 2014.

This technical report describes an interactive game environment designed to bring mothers and their adolescent daughters together to discuss three issues that have previously been shown in the literature to be of concern to families, as young girls transition...

A novel approach to teaching placement of a B-lynch suture: description of technique and validation of teaching model.

Journal of graduate medical education

Vetere PF, Wayock CP, Muscat J, Sicuranza G.
PMID: 23997884
J Grad Med Educ. 2012 Sep;4(3):367-9. doi: 10.4300/JGME-D-11-00186.1.

INTRODUCTION: Postpartum hemorrhage is a major cause of maternal morbidity and mortality throughout the world and uterine atony is the leading cause of postpartum hemorrhage. The B-Lynch brace suture is a fertility-sparing approach to treating intractable uterine atony at...

Showing 1 to 12 of 157 entries