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Showing 1 to 12 of 378 entries
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New measurements of high-momentum nucleons and short-range structures in nuclei.

Physical review letters

Fomin N, Arrington J, Asaturyan R, Benmokhtar F, Boeglin W, Bosted P, Bruell A, Bukhari MH, Christy ME, Chudakov E, Clasie B, Connell SH, Dalton MM, Daniel A, Day DB, Dutta D, Ent R, El Fassi L, Fenker H, Filippone BW, Garrow K, Gaskell D, Hill C, Holt RJ, Horn T, Jones MK, Jourdan J, Kalantarians N, Keppel CE, Kiselev D, Kotulla M, Lindgren R, Lung AF, Malace S, Markowitz P, McKee P, Meekins DG, Mkrtchyan H, Navasardyan T, Niculescu G, Opper AK, Perdrisat C, Potterveld DH, Punjabi V, Qian X, Reimer PE, Roche J, Rodriguez VM, Rondon O, Schulte E, Seely J, Segbefia E, Slifer K, Smith GR, Solvignon P, Tadevosyan V, Tajima S, Tang L, Testa G, Trojer R, Tvaskis V, Vulcan WF, Wasko C, Wesselmann FR, Wood SA, Wright J, Zheng X.
PMID: 22463628
Phys Rev Lett. 2012 Mar 02;108(9):092502. doi: 10.1103/PhysRevLett.108.092502. Epub 2012 Feb 29.

We present new measurements of electron scattering from high-momentum nucleons in nuclei. These data allow an improved determination of the strength of two-nucleon correlations for several nuclei, including light nuclei where clustering effects can, for the first time, be...

Dynamic stark control of torsional motion by a pair of laser pulses.

Physical review letters

Christensen L, Nielsen JH, Brandt CB, Madsen CB, Madsen LB, Slater CS, Lauer A, Brouard M, Johansson MP, Shepperson B, Stapelfeldt H.
PMID: 25170706
Phys Rev Lett. 2014 Aug 15;113(7):073005. doi: 10.1103/PhysRevLett.113.073005. Epub 2014 Aug 12.

The torsional motion of a molecule composed of two substituted benzene rings, linked by a single bond, is coherently controlled by a pair of strong (3×10^{13}  W cm^{-2}), nonresonant (800 nm) 200-fs-long laser pulses-both linearly polarized perpendicular to the...

Serum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) predict severity of liver disease in chronic hepatitis B.

Clinical and experimental gastroenterology

Li J, Verhaar AP, Pan Q, de Knegt RJ, Peppelenbosch MP.
PMID: 28860836
Clin Exp Gastroenterol. 2017 Aug 11;10:203-209. doi: 10.2147/CEG.S135526. eCollection 2017.

BACKGROUND AND AIM: Caspase-cleaved cytokeratin 18 (CK18-Asp396) is a potential clinically useful biomarker in liver disease as it is released from hepatocytes during apoptosis. In this study, we investigated serum CK18-Asp396 levels in chronic hepatitis B (CHB).PATIENTS AND METHODS:...

Towards Enhanced Performance Thin-film Composite Membranes via Surface Plasma Modification.

Scientific reports

Reis R, Dumée LF, Tardy BL, Dagastine R, Orbell JD, Schutz JA, Duke MC.
PMID: 27363670
Sci Rep. 2016 Jul 01;6:29206. doi: 10.1038/srep29206.

Advancing the design of thin-film composite membrane surfaces is one of the most promising pathways to deal with treating varying water qualities and increase their long-term stability and permeability. Although plasma technologies have been explored for surface modification of...

Identification of sample annotation errors in gene expression datasets.

Archives of toxicology

Lohr M, Hellwig B, Edlund K, Mattsson JS, Botling J, Schmidt M, Hengstler JG, Micke P, Rahnenführer J.
PMID: 26608184
Arch Toxicol. 2015 Dec;89(12):2265-72. doi: 10.1007/s00204-015-1632-4. Epub 2015 Nov 25.

The comprehensive transcriptomic analysis of clinically annotated human tissue has found widespread use in oncology, cell biology, immunology, and toxicology. In cancer research, microarray-based gene expression profiling has successfully been applied to subclassify disease entities, predict therapy response, and...

Visual pathway neurodegeneration winged by mitochondrial dysfunction.

Annals of clinical and translational neurology

Petzold A, Nijland PG, Balk LJ, Amorini AM, Lazzarino G, Wattjes MP, Gasperini C, van der Valk P, Tavazzi B, Lazzarino G, van Horssen J.
PMID: 25750919
Ann Clin Transl Neurol. 2015 Feb;2(2):140-50. doi: 10.1002/acn3.157. Epub 2014 Dec 17.

OBJECTIVES: To test for structural and functional contribution of mitochondrial dysfunction to neurodegeneration in multiple sclerosis (MS). A visual pathway model void of MS lesions was chosen in order to exclude neurodegeneration secondary to lesion related axonotmesis.METHODS: A single-centre...

Hippocampal Cortactin Levels are Reduced Following Spatial Working Memory Formation, an Effect Blocked by Chronic Calpain Inhibition.

Brain sciences

Olson ML, Ingebretson AE, Harmelink KM.
PMID: 26103422
Brain Sci. 2015 Jun 19;5(2):241-57. doi: 10.3390/brainsci5020241.

The mechanism by which the hippocampus facilitates declarative memory formation appears to involve, among other things, restructuring of the actin cytoskeleton within neuronal dendrites. One protein involved in this process is cortactin, which is an important link between extracellular...

Atypical femoral fracture in an osteogenesis imperfecta patient successfully treated with teriparatide.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Holm J, Eiken P, Hyldstrup L, Jensen JE.
PMID: 24936568
Endocr Pract. 2014 Oct;20(10):e187-90. doi: 10.4158/EP14141.CR.

OBJECTIVE: We report a case of a successfully healed atypical femoral fracture (AFF) following treatment with teriparatide in a patient with osteogenesis imperfecta (OI). To our knowledge, no successful treatment of AFFs with teriparatide in this subpopulation has ever...

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.

ACS medicinal chemistry letters

Mitchell LH, Drew AE, Ribich SA, Rioux N, Swinger KK, Jacques SL, Lingaraj T, Boriack-Sjodin PA, Waters NJ, Wigle TJ, Moradei O, Jin L, Riera T, Porter-Scott M, Moyer MP, Smith JJ, Chesworth R, Copeland RA.
PMID: 26101569
ACS Med Chem Lett. 2015 Apr 06;6(6):655-9. doi: 10.1021/acsmedchemlett.5b00071. eCollection 2015 Jun 11.

A novel aryl pyrazole series of arginine methyltransferase inhibitors has been identified. Synthesis of analogues within this series yielded the first potent, selective, small molecule PRMT6 inhibitor tool compound, EPZ020411. PRMT6 overexpression has been reported in several cancer types...

Nonlinear optical observation of coherent acoustic Dirac plasmons in thin-film topological insulators.

Nature communications

Glinka YD, Babakiray S, Johnson TA, Holcomb MB, Lederman D.
PMID: 27687867
Nat Commun. 2016 Sep 30;7:13054. doi: 10.1038/ncomms13054.

Low-energy collective electronic excitations exhibiting sound-like linear dispersion have been intensively studied both experimentally and theoretically for a long time. However, coherent acoustic plasmon modes appearing in time-domain measurements are rarely observed due to Landau damping by the single-particle...

Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.

ACS medicinal chemistry letters

Duncan KW, Rioux N, Boriack-Sjodin PA, Munchhof MJ, Reiter LA, Majer CR, Jin L, Johnston LD, Chan-Penebre E, Kuplast KG, Porter Scott M, Pollock RM, Waters NJ, Smith JJ, Moyer MP, Copeland RA, Chesworth R.
PMID: 26985292
ACS Med Chem Lett. 2015 Dec 02;7(2):162-6. doi: 10.1021/acsmedchemlett.5b00380. eCollection 2016 Feb 11.

The recent publication of a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) provides the scientific community with in vivo-active tool compound EPZ015666 (GSK3235025) to probe the underlying pharmacology of this key enzyme. Herein, we report the design...

Acute influenza virus-associated encephalitis and encephalopathy in adults: a challenging diagnosis.

JMM case reports

Meijer WJ, Linn FH, Wensing AM, Leavis HL, van Riel D, GeurtsvanKessel CH, Wattjes MP, Murk JL.
PMID: 28348797
JMM Case Rep. 2016 Dec 19;3(6):e005076. doi: 10.1099/jmmcr.0.005076. eCollection 2016 Dec.

No abstract available.

Showing 1 to 12 of 378 entries