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Showing 1 to 12 of 176 entries
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Development of a UC781 releasing polyethylene vinyl acetate vaginal ring.

Drug delivery and translational research

McConville C, Major I, Friend DR, Clark MR, Malcolm RK.
PMID: 25787327
Drug Deliv Transl Res. 2012 Dec;2(6):489-97. doi: 10.1007/s13346-012-0101-3.

UC781 is potent, hydrophobic, non-nucleotide reverse transcriptase inhibitor (NNRTI) against the human immunodeficiency virus (HIV). UC781 is currently being investigated for use as a potential HIV microbicide. A study in rhesus macaques demonstrated that a 100-mg UC781-loaded silicone elastomer...

Enantiopurity and absolute configuration determination of arene cis-dihydrodiol metabolites and derivatives using chiral boronic acids.

Chirality

Boyd DR, Sharma ND, Goodrich PA, Malone JF, McConville G, Harrison JS, Stevenson PJ, Allen CCR.
PMID: 29024058
Chirality. 2018 Jan;30(1):5-18. doi: 10.1002/chir.22764. Epub 2017 Oct 11.

The relative merits of the methods employed to determine enantiomeric excess (ee) values and absolute configurations of chiral arene and alkene cis-1,2-diol metabolites, including boronate formation, using racemic or enantiopure (+) and (-)-2-(1-methoxyethyl)phenylboronic acid (MEPBA), are discussed. Further applications...

A Novel High-Yield Synthesis of Substituted Isoindolequinones.

The Journal of organic chemistry

Chakraborty M, McConville DB, Koser GF, Tessier CA, Saito T, Rinaldi PL, Youngs WJ.
PMID: 11671931
J Org Chem. 1997 Nov 14;62(23):8193-8197. doi: 10.1021/jo971671r.

The high-yield, general, one-pot synthesis of substituted isoindolequinones, a group of important radiosensitizers which sensitize hypoxic cells to the lethal effect of radiation in cancer radiotherapy, is described. Primary amines react with 2,3-bis[2-(trimethylsilyl)ethynyl]-5,6-dimethylhydroquinone (2) in methanol at room temperature...

Reactions of Primary and Secondary Amines with Substituted Hydroquinones: Nuclear Amination, Side-Chain Amination, and Indolequinone Formation.

The Journal of organic chemistry

Chakraborty M, McConville DB, Niu Y, Tessier CA, Youngs WJ.
PMID: 11672419
J Org Chem. 1998 Oct 16;63(21):7563-7567. doi: 10.1021/jo980541v.

No abstract available.

Surface electron accumulation and the charge neutrality level in In2O3.

Physical review letters

King PD, Veal TD, Payne DJ, Bourlange A, Egdell RG, McConville CF.
PMID: 18851315
Phys Rev Lett. 2008 Sep 12;101(11):116808. doi: 10.1103/PhysRevLett.101.116808. Epub 2008 Sep 11.

High-resolution x-ray photoemission spectroscopy, infrared reflectivity and Hall effect measurements, combined with surface space-charge calculations, are used to show that electron accumulation occurs at the surface of undoped single-crystalline In2O3. From a combination of measurements performed on undoped and...

Intrinsic electron accumulation at clean InN surfaces.

Physical review letters

Mahboob I, Veal TD, McConville CF, Lu H, Schaff WJ.
PMID: 14753893
Phys Rev Lett. 2004 Jan 23;92(3):036804. doi: 10.1103/PhysRevLett.92.036804. Epub 2004 Jan 22.

The electronic structure of clean InN(0001) surfaces has been investigated by high-resolution electron-energy-loss spectroscopy of the conduction band electron plasmon excitations. An intrinsic surface electron accumulation layer is found to exist and is explained in terms of a particularly...

Spectrum of the isotropic diffuse gamma-ray emission derived from first-year Fermi Large Area Telescope data.

Physical review letters

Abdo AA, Ackermann M, Ajello M, Atwood WB, Baldini L, Ballet J, Barbiellini G, Bastieri D, Baughman BM, Bechtol K, Bellazzini R, Berenji B, Blandford RD, Bloom ED, Bonamente E, Borgland AW, Bregeon J, Brez A, Brigida M, Bruel P, Burnett TH, Buson S, Caliandro GA, Cameron RA, Caraveo PA, Casandjian JM, Cavazzuti E, Cecchi C, Celik O, Charles E, Chekhtman A, Cheung CC, Chiang J, Ciprini S, Claus R, Cohen-Tanugi J, Cominsky LR, Conrad J, Cutini S, Dermer CD, de Angelis A, de Palma F, Digel SW, Di Bernardo G, do Couto e Silva E, Drell PS, Drlica-Wagner A, Dubois R, Dumora D, Farnier C, Favuzzi C, Fegan SJ, Focke WB, Fortin P, Frailis M, Fukazawa Y, Funk S, Fusco P, Gaggero D, Gargano F, Gasparrini D, Gehrels N, Germani S, Giebels B, Giglietto N, Giommi P, Giordano F, Glanzman T, Godfrey G, Grenier IA, Grondin MH, Grove JE, Guillemot L, Guiriec S, Gustafsson M, Hanabata Y, Harding AK, Hayashida M, Hughes RE, Itoh R, Jackson MS, Jóhannesson G, Johnson AS, Johnson RP, Johnson TJ, Johnson WN, Kamae T, Katagiri H, Kataoka J, Kawai N, Kerr M, Knödlseder J, Kocian ML, Kuehn F, Kuss M, Lande J, Latronico L, Lemoine-Goumard M, Longo F, Loparco F, Lott B, Lovellette MN, Lubrano P, Madejski GM, Makeev A, Mazziotta MN, McConville W, McEnery JE, Meurer C, Michelson PF, Mitthumsiri W, Mizuno T, Moiseev AA, Monte C, Monzani ME, Morselli A, Moskalenko IV, Murgia S, Nolan PL, Norris JP, Nuss E, Ohsugi T, Omodei N, Orlando E, Ormes JF, Paneque D, Panetta JH, Parent D, Pelassa V, Pepe M, Pesce-Rollins M, Piron F, Porter TA, Rainò S, Rando R, Razzano M, Reimer A, Reimer O, Reposeur T, Ritz S, Rochester LS, Rodriguez AY, Roth M, Ryde F, Sadrozinski HF, Sanchez D, Sander A, Saz Parkinson PM, Scargle JD, Sellerholm A, Sgrò C, Shaw MS, Siskind EJ, Smith DA, Smith PD, Spandre G, Spinelli P, Starck JL, Strickman MS, Strong AW, Suson DJ, Tajima H, Takahashi H, Takahashi T, Tanaka T, Thayer JB, Thayer JG, Thompson DJ, Tibaldo L, Torres DF, Tosti G, Tramacere A, Uchiyama Y, Usher TL, Vasileiou V, Vilchez N, Vitale V, Waite AP, Wang P, Winer BL, Wood KS, Ylinen T, Ziegler M.
PMID: 20366411
Phys Rev Lett. 2010 Mar 12;104(10):101101. doi: 10.1103/PhysRevLett.104.101101. Epub 2010 Mar 08.

We report on the first Fermi Large Area Telescope (LAT) measurements of the so-called "extragalactic" diffuse gamma-ray emission (EGB). This component of the diffuse gamma-ray emission is generally considered to have an isotropic or nearly isotropic distribution on the...

Accurate ultra-low-energy secondary ion mass spectrometry analysis of wide bandgap GaN/In(x)Ga(1-x)N structures using optical conductivity enhancement.

Rapid communications in mass spectrometry : RCM

Morris RJ, Dowsett MG, Beanland R, Parbrook PJ, McConville CF.
PMID: 20552690
Rapid Commun Mass Spectrom. 2010 Jul 30;24(14):2122-6. doi: 10.1002/rcm.4623.

Ultra-low-energy secondary ion mass spectrometry has been used to undertake a structural analysis of GaN-In(x)Ga(1-x)N (x approximately 0.25) quantum wells used in optoelectronic devices. The high resistivity of intrinsic GaN-In(x)Ga(1-x)N restricts the necessary electrical path between the analyzed area...

Recrystallization of highly-mismatched Be(x)Zn(1-x)O alloys: formation of a degenerate interface.

ACS applied materials & interfaces

Park DS, Vasheghani Farahani SK, Walker M, Mudd JJ, Wang H, Krupski A, Thorsteinsson EB, Seghier D, Choi CJ, Youn CJ, McConville CF.
PMID: 25289707
ACS Appl Mater Interfaces. 2014 Nov 12;6(21):18758-68. doi: 10.1021/am5043388. Epub 2014 Oct 21.

We investigate the effect of thermally induced phase transformations on a metastable oxide alloy film, a multiphase Be(x)Zn(1-x)O (BZO), grown on Al2O3(0001) substrate for annealing temperatures in the range of 600-950 °C. A pronounced structural transition is shown together...

Potential of conjugal transfer as a strategy for the introduction of recombinant genetic material into strains of lactobacillus helveticus .

Applied and environmental microbiology

Collins MA, McConville KJ, McReynolds C, Thompson JK.
PMID: 10223978
Appl Environ Microbiol. 1999 May;65(5):1910-4. doi: 10.1128/AEM.65.5.1910-1914.1999.
Free PMC Article

Cointegrates generated between a plasmid pIP501 deletion derivative (pVA797) and nonconjugative shuttle vector pSA3 were confirmed as capable of exconjugation from lactococci into a range of strains of Lactobacillus helveticus with the concomitant expression of a recombinant gene. The...

Simple x-ray standing-wave technique and its application to the investigation of the Cu(111) ( sqrt 3 sqrt 3 )R30 degrees -Cl structure.

Physical review letters

Crapper MD, Jones RG, McConville CF, Prince NP, Riley CE, Seymour DL, Woodruff DP.
PMID: 10034442
Phys Rev Lett. 1987 Apr 06;58(14):1460-1462. doi: 10.1103/PhysRevLett.58.1460.

No abstract available.

Plasmon excitations and accumulation layers in heavily doped InAs(001).

Physical review. B, Condensed matter

Bell GR, Jones TS, McConville CF.
PMID: 9986114
Phys Rev B Condens Matter. 1996 Jul 15;54(4):2654-2661. doi: 10.1103/physrevb.54.2654.

No abstract available.

Showing 1 to 12 of 176 entries