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Showing 1 to 12 of 429 entries
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Cardio-oncology: what you need to know now for clinical practice and echocardiography.

Echo research and practice

Larsen CM, Mulvagh SL.
PMID: 28254996
Echo Res Pract. 2017 Mar;4(1):R33-R41. doi: 10.1530/ERP-17-0013. Epub 2017 Mar 02.

Cardio-oncology is a rapidly growing field aimed at minimizing the effects of cardiovascular morbidity and mortality in cancer survivors. To meet this aim, patients are assessed at baseline to define their risk of cardiotoxicity and then followed closely during...

Contractility assessment in enzymatically isolated cardiomyocytes.

Biophysical reviews

Bazan C, Barba DT, Hawkins T, Nguyen H, Anderson S, Vazquez-Hidalgo E, Lemus R, Moore J, Mitchell J, Martinez J, Moore D, Larsen J, Paolini P.
PMID: 28510074
Biophys Rev. 2012 Sep;4(3):231-243. doi: 10.1007/s12551-012-0082-y. Epub 2012 Sep 01.

The use of enzymatically isolated cardiac myocytes is ubiquitous in modern cardiovascular research. Parallels established between cardiomyocyte shortening responses and those of intact tissue make the cardiomyocyte an invaluable experimental model of cardiac function. Much of our understanding regarding...

July consultation #7.

Journal of cataract and refractive surgery

Larsen CL.
PMID: 27669089
J Cataract Refract Surg. 2016 Jul;42(7):1103. doi: 10.1016/j.jcrs.2016.06.016. Epub 2016 Aug 02.

No abstract available.

College Freshmen Students' Perspectives on Weight Gain Prevention in the Digital Age: Web-Based Survey.

JMIR public health and surveillance

Monroe CM, Turner-McGrievy G, Larsen CA, Magradey K, Brandt HM, Wilcox S, Sundstrom B, West DS.
PMID: 29025698
JMIR Public Health Surveill. 2017 Oct 12;3(4):e71. doi: 10.2196/publichealth.7875.

BACKGROUND: College freshmen are highly vulnerable to experiencing weight gain, and this phenomenon is associated with an increased risk of chronic diseases and mortality in older adulthood. Technology offers an attractive and scalable way to deliver behavioral weight gain...

Clinicopathologic Features of Membranous-Like Glomerulopathy With Masked IgG Kappa Deposits.

Kidney international reports

Larsen CP, Boils CL, Cossey LN, Sharma SG, Walker PD.
PMID: 29142932
Kidney Int Rep. 2016 Aug 24;1(4):299-305. doi: 10.1016/j.ekir.2016.08.012. eCollection 2016 Nov.

INTRODUCTION: Ig deposits identified on renal biopsy samples by paraffin immunofluorescence that show negative staining by routine immunofluorescence on frozen tissue have become known as "masked" deposits. Membranous-like glomerulopathy with masked IgG kappa (κ) deposits is a recently recognized...

Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay.

Temperature (Austin, Tex.)

Touska F, Winter Z, Mueller A, Vlachova V, Larsen J, Zimmermann K.
PMID: 27227099
Temperature (Austin). 2016 Mar 02;3(1):77-91. doi: 10.1080/23328940.2015.1135689. eCollection 2016.

Currently available behavioral assays to quantify normal cold sensitivity, cold hypersensitivity and cold hyperalgesia in mice have betimes created conflicting results in the literature. Some only capture a limited spectrum of thermal experiences, others are prone to experimenter bias...

A new family with an activating mutation (G431S) in the TSH receptor gene: a phenotype discussion and review of the literature.

International journal of pediatric endocrinology

Larsen CC, Karaviti LP, Seghers V, Weiss RE, Refetoff S, Dumitrescu AM.
PMID: 25873976
Int J Pediatr Endocrinol. 2014;2014(1):23. doi: 10.1186/1687-9856-2014-23. Epub 2014 Nov 17.

Germline nonautoimmune hyperthyroidism due to an activating mutation in the thyroid stimulating hormone receptor gene is an uncommon disease. To date 32 different mutations have been described. The severity of the hyperthyroid symptoms is variable and phenotype differences have...

Organocatalytic stereoselective [8+2] and [6+4] cycloadditions.

Nature chemistry

Mose R, Preegel G, Larsen J, Jakobsen S, Iversen EH, Jørgensen KA.
PMID: 28430196
Nat Chem. 2017 May;9(5):487-492. doi: 10.1038/nchem.2682. Epub 2016 Dec 19.

Cycloadditions that involve more than six π electrons are termed higher-order cycloadditions and are an excellent tool for solving complex synthetic challenges, as they provide direct access to polycyclic scaffolds that contain medium-sized rings. They have interesting synthetic potential...

Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts.

ACS medicinal chemistry letters

Cruz PG, Fribley AM, Miller JR, Larsen MJ, Schultz PJ, Jacob RT, Tamayo-Castillo G, Kaufman RJ, Sherman DH.
PMID: 26288688
ACS Med Chem Lett. 2015 Jul 06;6(8):877-81. doi: 10.1021/acsmedchemlett.5b00127. eCollection 2015 Aug 13.

As part of the International Cooperative Biodiversity Groups (ICBG) Program, we were interested in identifying biologically active unfolded protein response (UPR) inducing compounds from marine microorganisms isolated from Costa Rican biota. With this aim in mind we have now...

Smoking and renal function in people living with human immunodeficiency virus: a Danish nationwide cohort study.

Clinical epidemiology

Ahlström MG, Feldt-Rasmussen B, Legarth R, Kronborg G, Pedersen C, Larsen CS, Gerstoft J, Obel N.
PMID: 26357490
Clin Epidemiol. 2015 Aug 28;7:391-9. doi: 10.2147/CLEP.S83530. eCollection 2015.

INTRODUCTION: Smoking is a main risk factor for morbidity and mortality in people living with human immunodeficiency virus (PLHIV), but its potential association with renal impairment remains to be established.METHODS: We did a nationwide population-based cohort study in Danish...

The stereoselective formation of highly substituted CF3-dihydropyrans as versatile building blocks.

Chemical communications (Cambridge, England)

Donslund BS, Monleón A, Larsen J, Ibsen L, Jørgensen KA.
PMID: 26225818
Chem Commun (Camb). 2015 Sep 14;51(71):13666-9. doi: 10.1039/c5cc04874e.

The highly enantioselective dienamine-mediated formation of 5-bromo-6-(trifluoromethyl)-3,4-dihydro-2H-pyrans from α,β-unsaturated aldehydes and α-bromo-(trifluoromethyl)-enones employing a C2-symmetric aminocatalyst is described. The products are demonstrated to be applicable in coupling reactions directly onto the ring, thereby granting access to a broad scope...

APOL1 Polymorphisms in a Deceased Donor and Early Presentation of Collapsing Glomerulopathy and Focal Segmental Glomerulosclerosis in Two Recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Shah PB, Cooper JE, Lucia MS, Boils C, Larsen CP, Wiseman AC.
PMID: 26849829
Am J Transplant. 2016 Jun;16(6):1923-1927. doi: 10.1111/ajt.13748. Epub 2016 Mar 29.

Two common polymorphisms in APOL1 (G1 and G2) are conserved in persons of African ancestry, and the presence of two polymorphisms (commonly referred to as risk variants) has been identified as a risk factor for chronic kidney disease and...

Showing 1 to 12 of 429 entries