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Showing 1 to 12 of 86 entries
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[Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France].

Bégaud B, Evreux JC, Jouglard J, Lagier G.
PMID: 4002188
Therapie. 1985 Mar-Apr;40(2):111-8.

No abstract available.

[Presentation of data in drug surveillance and bases for a decision].

Lagier G.
PMID: 3809779
Rev Med Interne. 1986 Nov;41-4.

Data presentation is a fundamental step in drug surveillance, for it makes it possible, after methodical analysis of the information obtained, to draw conclusions which may lead to a final decision concerning the product. Several items providing the basis...

[Detection of drug-induced nephrotoxicity].

Fillastre JP, Baud L, Baumelou A, Blanchard J, Bonvalet JP, Champey Y, Druet P, Glomot R, Imbs JL, Lagier G.
PMID: 3747540
J Pharmacol. 1986;17:41-50.

This is a report of a round table organized during the second meeting of Clinical Pharmacology held in Giens (France) in September 1985. At the beginning of the meeting, the clinical aspects of drug-induced nephrotoxicity were reviewed. Thus we...

Suppression of arrhythmias within hours after a single oral dose of amiodarone and relation to plasma and myocardial concentrations.

Escoubet B, Coumel P, Poirier JM, Maison-Blanche P, Jaillon P, Leclercq JF, Menasche P, Cheymol G, Piwnica A, Lagier G.
PMID: 3976511
Am J Cardiol. 1985 Mar 01;55(6):696-702. doi: 10.1016/0002-9149(85)90139-0.

In 65 patients a single oral dose of amiodarone (30 mg/kg) produced an antiarrhythmic effect on supraventricular or ventricular arrhythmias within 3 to 8 hours and lasted for 17 to 19 hours. On the second day a 15-mg/kg dose...

[Undesirable effects of drugs. Sampling of various publications appearing 1974-1975 on the undesirable effects of drugs].

Lechat P, Lagier G, Fontagné J.
PMID: 785683
Therapie. 1976 Jan-Feb;31(1):129-45.

No abstract available.

[Criteria of imputation of acute hepatitis to a drug. Results of consensus meetings].

Danan G, Bénichou C, Begaud B, Biour M, Couzigou P, Evreux JC, Lagier G, Berthelot P, Benhamou JP.
PMID: 3308618
Gastroenterol Clin Biol. 1987 Aug-Sep;11(8):581-5.

The use of an official drug adverse reaction assessment procedure became compulsory in France in 1984. The method proposes various qualifications for chronologic and semiologic criteria but does not define them. Consensus meetings have been organized in order to...

[The efficacy of pharmacovigilance--principles and proposals].

Evreux JC, Lagier G.
PMID: 1013951
Therapie. 1976 Sep-Oct;31(5):581-6.

No abstract available.

[Bismuth encephalopathies outside France (author's transl)].

Lagier G.
PMID: 7423419
Therapie. 1980 May-Jun;35(3):315-7.

No abstract available.

[Interstitial pneumopathies: criteria of drug side-effects. Results of consensus meetings].

Fournier M, Camus P, Benichou C, Danan G, Begaud B, Castot A, Lagier G, Brune J, Pariente R, Chrétien J.
PMID: 2529493
Presse Med. 1989 Sep 2-9;18(27):1333-6.

Since 1984, the use of the official method for determining the responsibility of drugs in side-effects has been compulsory in France. This method offers, but does not define, different qualificatives for chronological and semeiological criteria. Consensus workshops have been...

[Hypoglycemia in 2 patients treated with perhexiline maleate].

Dally S, Lagier G, Assan R, Gaultier M.
PMID: 866152
Nouv Presse Med. 1977 May 07;6(19):1643-4, 1649.

Hypoglycaemia occurred in two patients treated with perhexiline maleate. The responsibility of the medication is discussed in each case. Blood insulin levels were increased. Blood perhexiline levels decreased very rapidly in the first patient, though much more slowly in...

[Pharmacologic criteria for medical substitution in opiate dependence].

Montastruc JL, Arnaud P, Barbier C, Berlin I, Gatignol C, Haramburu F, Lagier G, Lapeyre-Mestre M, Mallaret M, Micaleff J.
PMID: 12942851
Therapie. 2003 Mar-Apr;58(2):123-5. doi: 10.2515/therapie:2003017.

Our goal was to establish new pharmacological criteria for a drug to be used in the treatment of opioid dependence. We propose the following six pharmacodynamic and pharmacokinetic criteria: (i) the same pharmacodynamic properties as the drug being substituted;...

[Prognostic factors in acute digitalis poisoning (author's transl)].

Dally S, Alperovitch A, Lagier G, Bismuth C, Fournier E.
PMID: 7267327
Nouv Presse Med. 1981 Jun 20;10(27):2257-60.

The prognostic significance of various clinical and biochemical factors was investigated in 179 patients who had absorbed more than 2 mg of digitoxin. The mortality rate in this series was 17%. Supraventricular arrythmias had no influence on prognosis, but...

Showing 1 to 12 of 86 entries