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Showing 1 to 12 of 92 entries
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Targeted Temperature Management in Pediatric Central Nervous System Disease.

Current treatment options in pediatrics

Newmyer R, Mendelson J, Pang D, Fink EL.
PMID: 26042193
Curr Treat Options Pediatr. 2015 Mar 01;1(1):38-47. doi: 10.1007/s40746-014-0008-y.

Acute central nervous system conditions due to hypoxic-ischemic encephalopathy, traumatic brain injury (TBI), status epilepticus, and central nervous system infection/inflammation, are a leading cause of death and disability in childhood. There is a critical need for effective neuroprotective therapies...

Metabolic engineering of yeasts by heterologous enzyme production for degradation of cellulose and hemicellulose from biomass: a perspective.

Frontiers in microbiology

Kricka W, Fitzpatrick J, Bond U.
PMID: 24795706
Front Microbiol. 2014 Apr 22;5:174. doi: 10.3389/fmicb.2014.00174. eCollection 2014.

This review focuses on current approaches to metabolic engineering of ethanologenic yeast species for the production of bioethanol from complex lignocellulose biomass sources. The experimental strategies for the degradation of the cellulose and xylose-components of lignocellulose are reviewed. Limitations...

Microchip-based Devices for Molecular Diagnosis of Genetic Diseases.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology

Cheng J, Fortina P, Surrey S, Kricka LJ, Wilding P.
PMID: 10462559
Mol Diagn. 1996 Sep;1(3):183-200. doi: 10.1016/s1084-8592(96)70004-8.

Microchips, constructed with a variety of microfabrication technologies (photolithography, micropatterning, microjet printing, light-directed chemical synthesis, laser stereochemical etching, and microcontact printing) are being applied to molecular biology. The new microchip-based analytical devices promise to solve the analytical problems faced...

Noise on Fluorescence Correlation Spectroscopy.

Journal of colloid and interface science

Starchev K, Ricka J, Buffle J.
PMID: 11112305
J Colloid Interface Sci. 2001 Jan 01;233(1):50-55. doi: 10.1006/jcis.2000.7229.

The time dependence of the noise and the signal-to-noise (SN) ratio of the fluorescence correlation spectroscopy (FCS) autocorrelation function is obtained from replica measurements of standard dextran solutions. The noise dependence on the delay time is fitted by a...

Editorial.

Luminescence : the journal of biological and chemical luminescence

Kricka LJ.
PMID: 10398562
Luminescence. 1999 Mar;14(2):67. doi: 10.1002/(SICI)1522-7243(199903/04)14:2<67::AID-BIO542>3.0.CO;2-Y.

No abstract available.

Enhanced chemiluminescent enzyme immunoassays.

Parasitology today (Personal ed.)

Kricka LJ, Thorpe GH.
PMID: 15462796
Parasitol Today. 1986 Apr;2(4):123-5. doi: 10.1016/0169-4758(86)90047-5.

No abstract available.

Enhanced chemiluminescence determination of alpha-amylase by use of amylose labelled with horseradish peroxidase.

Talanta

Kricka LJ, Marcinkowski JM, Wilding P, Lekhakula S.
PMID: 18965051
Talanta. 1990 Oct;37(10):971-4. doi: 10.1016/0039-9140(90)80136-4.

An enhanced chemiluminescence method for determining soluble and immobilized alpha-amylase has been developed, based on use of an insoluble amylose substrate labelled with horseradish peroxidase. Soluble peroxidase-labelled fragments of the substrate, released by the action of alpha-amylase, are quantified...

Absolute measurement of molecular two-photon absorption cross-sections using a fluorescence saturation technique.

Optics express

Kauert M, Stoller PC, Frenz M, Ricka J.
PMID: 19529221
Opt Express. 2006 Sep 04;14(18):8434-47. doi: 10.1364/oe.14.008434.

We have developed a fluorescence saturation technique for accurate measurements of the absolute molecular two-photon absorption (TPA) cross-section of fluorescent dyes. We determine the TPA crosssection both from measurements at excitation intensities well below saturation onset (in the square...

Control of functional responses via reversible oxygen loss in La₁-xSrxFeO₃-δ films.

Advanced materials (Deerfield Beach, Fla.)

Xie Y, Scafetta MD, Sichel-Tissot RJ, Moon EJ, Devlin RC, Wu H, Krick AL, May SJ.
PMID: 24734299
Adv Mater. 2014 Mar 05;26(9):1434-8. doi: 10.1002/adma.201304374.

La0.3 Sr0.7 FeO3-δ films undergo dramatic changes in electronic and optical properties due to reversible oxygen loss induced by low-temperature heating. This mechanism to control the functional properties may serve as a platform for new devices or sensors in...

α-Amination of keto-nitrones via multihetero-Cope rearrangement employing an imidoyl chloride reagent.

Chemical communications (Cambridge, England)

Malinowski JT, Malow EJ, Johnson JS.
PMID: 22733086
Chem Commun (Camb). 2012 Aug 07;48(61):7568-70. doi: 10.1039/c2cc33401a. Epub 2012 Jun 26.

α-Aminations of ketone-derived nitrones have been developed via [3,3]-rearrangement of the intermediates generated upon condensation with imidoyl chlorides. Careful reagent selection provides synthetically attractive amino protecting groups. The enediamide or α'-carbamoyl enamide products can be hydrolyzed to the desired...

CAT-2003: A novel sterol regulatory element-binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3-Leiden mice.

Hepatology communications

Zimmer M, Bista P, Benson EL, Lee DY, Liu F, Picarella D, Vega RB, Vu CB, Yeager M, Ding M, Liang G, Horton JD, Kleemann R, Kooistra T, Morrison MC, Wielinga PY, Milne JC, Jirousek MR, Nichols AJ.
PMID: 29404461
Hepatol Commun. 2017 May 12;1(4):311-325. doi: 10.1002/hep4.1042. eCollection 2017 Jun.

CAT-2003 is a novel conjugate of eicosapentaenoic acid (EPA) and niacin designed to be hydrolyzed by fatty acid amide hydrolase to release EPA inside cells at the endoplasmic reticulum. In cultured liver cells, CAT-2003 blocked the maturation of sterol...

Deep divergence of Red-crowned Ant Tanager (.

PeerJ

Ramírez-Barrera SM, Hernández-Baños BE, Jaramillo-Correa JP, Klicka J.
PMID: 30225165
PeerJ. 2018 Sep 12;6:e5496. doi: 10.7717/peerj.5496. eCollection 2018.

Many neotropical species have a complex history of diversification as a result of the influence of geographical, ecological, climatic, and geological factors that determine the distribution of populations within a lineage. Phylogeography identifies such populations, determines their geographic distributions,...

Showing 1 to 12 of 92 entries