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Showing 1 to 12 of 25 entries
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Should Deferred Stenting Still Be Considered in ST-Elevation Myocardial Infarction with High Thrombus Burden?.

Journal of cardiovascular development and disease

Sakellariou XM, Katsanos GI, Efstathopoulos AP, Sfairopoulos DG, Stamatis KV, Pappas SD, Kolettis TM, Nikas DN.
PMID: 34063837
J Cardiovasc Dev Dis. 2021 May 21;8(6). doi: 10.3390/jcdd8060059.

Patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) may demonstrate distal microvascular embolization of thrombotic materials. We retrospectively examined 20 cases displaying extensive thrombus in the infarct-related artery (IRA), treated either with a two-step...

Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity.

Stem cells international

Maltabe VA, Barka E, Kontonika M, Florou D, Kouvara-Pritsouli M, Roumpi M, Agathopoulos S, Kolettis TM, Kouklis P.
PMID: 28101109
Stem Cells Int. 2016;2016:8305624. doi: 10.1155/2016/8305624. Epub 2016 Dec 22.

Embryonic Stem (ES) or induced Pluripotent Stem (iPS) cells are important sources for cardiomyocyte generation, targeted for regenerative therapies. Several in vitro protocols are currently utilized for their differentiation, but the value of cell-based approaches remains unclear. Here, we...

Optical Coherence Tomography Facilitating Early Withdrawal of Antiplatelet Agents in a High-Bleeding Risk Patient.

JACC. Case reports

Gkirdis I, Nikas DN, Bampali T, Kolettis TM.
PMID: 34317445
JACC Case Rep. 2020 Jul 15;2(8):1186-1191. doi: 10.1016/j.jaccas.2020.04.049. eCollection 2020 Jul.

Optical coherence tomography (OCT) can guide percutaneous coronary interventions to optimize results, thus minimizing the risk of stent thrombosis. We present the case of a cancer patient, paroxysmal atrial fibrillation, and unstable angina who underwent OCT-guided complex percutaneous coronary...

Myocardial perfusion SPECT as a potential mediator on circulating chromogranin A in patients with old myocardial infarction.

Hellenic journal of nuclear medicine

Xourgia X, Tsiouris S, Kolettis T, Goudevenos I, Arseniou A, Fotopoulos AD.
PMID: 34352046
Hell J Nucl Med. 2021 May-Aug;24(2):114-121. doi: 10.1967/s002449912351. Epub 2021 Aug 06.

OBJECTIVE: Chromogranin A (CgA) is a soluble polypeptide stored within and released from secretory granules of endocrine and other cell types (including cardiomyocytes); CgA appears to be a marker of the overall neuroendocrine activity. Increased levels of serum CgA...

Treatment of Mobile Right Heart Thrombi.

European journal of case reports in internal medicine

Sakellariou XM, Efstathopoulos A, Stamatis KV, Nikas DN, Kolettis TM.
PMID: 33313001
Eur J Case Rep Intern Med. 2020 Sep 17;7(12):001918. doi: 10.12890/2020_001918. eCollection 2020.

Right heart thrombi are detected in approximately 4% of patients with pulmonary embolism. The associated mortality is high, but the optimal strategy remains controversial. We report a case of a large mobile right heart thrombus, complicated by embolism of...

Autonomic Responses during Labor: Potential Implications for Takotsubo Syndrome.

Journal of cardiovascular development and disease

Papadopoulos GE, Evaggelou TI, Moulias EK, Tsonis O, Zekios KC, Nikas DN, Tzimas P, Paschopoulos M, Kolettis TM.
PMID: 34821705
J Cardiovasc Dev Dis. 2021 Nov 07;8(11). doi: 10.3390/jcdd8110152.

Takotsubo syndrome is a serious complication of labor. Although the pathophysiologic role of excessive sympathetic activation is established in this process, concurrent vagal responses have not been adequately described. Moreover, it remains unclear whether autonomic activity depends on the...

Sympathetic and Vagal Responses Elicited by Acute Stress in Rats.

Cureus

Mouchtouri ET, Lekkas P, Delis F, Pantelakis E, Mourouzis I, Pantos C, Kolettis TM.
PMID: 33364122
Cureus. 2020 Nov 20;12(11):e11602. doi: 10.7759/cureus.11602.

Introduction Acute emotional stress triggers autonomic responses that affect sympathovagal balance. However, the temporal pattern of changes in each autonomic arm during stress and recovery remains unclear. Therefore, we analyzed separately sympathetic and vagal activity, elicited by acute unpredictable...

Understanding treatment response in congenital thrombotic thrombocytopenic purpura to aid in pregnancy counseling and management.

American journal of obstetrics and gynecology

Phelps AJD, Kolettis D.
PMID: 34838805
Am J Obstet Gynecol. 2021 Nov 26; doi: 10.1016/j.ajog.2021.11.1359. Epub 2021 Nov 26.

No abstract available.

Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil.

medRxiv : the preprint server for health sciences

Faria NR, Mellan TA, Whittaker C, Claro IM, Candido DDS, Mishra S, Crispim MAE, Sales FC, Hawryluk I, McCrone JT, Hulswit RJG, Franco LAM, Ramundo MS, de Jesus JG, Andrade PS, Coletti TM, Ferreira GM, Silva CAM, Manuli ER, Pereira RHM, Peixoto PS, Kraemer MU, Gaburo N, Camilo CDC, Hoeltgebaum H, Souza WM, Rocha EC, de Souza LM, de Pinho MC, Araujo LJT, Malta FSV, de Lima AB, Silva JDP, Zauli DAG, de S Ferreira AC, Schnekenberg RP, Laydon DJ, Walker PGT, Schlüter HM, Dos Santos ALP, Vidal MS, Del Caro VS, Filho RMF, Dos Santos HM, Aguiar RS, Modena JLP, Nelson B, Hay JA, Monod M, Miscouridou X, Coupland H, Sonabend R, Vollmer M, Gandy A, Suchard MA, Bowden TA, Pond SLK, Wu CH, Ratmann O, Ferguson NM, Dye C, Loman NJ, Lemey P, Rambaut A, Fraiji NA, Carvalho MDPSS, Pybus OG, Flaxman S, Bhatt S, Sabino EC.
PMID: 33688664
medRxiv. 2021 Mar 03; doi: 10.1101/2021.02.26.21252554.

Cases of SARS-CoV-2 infection in Manaus, Brazil, resurged in late 2020, despite high levels of previous infection there. Through genome sequencing of viruses sampled in Manaus between November 2020 and January 2021, we identified the emergence and circulation of...

Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone.

Case reports in medicine

Kotsia AP, Dimitriadis G, Baltogiannis GG, Kolettis TM.
PMID: 22474460
Case Rep Med. 2012;2012:673019. doi: 10.1155/2012/673019. Epub 2012 Mar 05.

We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days. This prolonged course for QTc normalization may...

Central Sympathetic Activation and Arrhythmogenesis during Acute Myocardial Infarction: Modulating Effects of Endothelin-B Receptors.

Frontiers in cardiovascular medicine

Kolettis TM, Kontonika M, Barka E, Daskalopoulos EP, Baltogiannis GG, Tourmousoglou C, Papalois A, Kyriakides ZS.
PMID: 26664878
Front Cardiovasc Med. 2015 Feb 23;2:6. doi: 10.3389/fcvm.2015.00006. eCollection 2015.

Sympathetic activation during acute myocardial infarction (MI) is an important arrhythmogenic mechanism, but the role of central autonomic inputs and their modulating factors remain unclear. Using the in vivo rat-model, we examined the effects of clonidine, a centrally acting...

Autonomic function and ventricular tachyarrhythmias during acute myocardial infarction.

World journal of experimental medicine

Kolettis TM.
PMID: 30191139
World J Exp Med. 2018 Aug 30;8(1):8-11. doi: 10.5493/wjem.v8.i1.8. eCollection 2018 Aug 30.

Most cases of sudden cardiac death are attributed to sustained ventricular tachyarrhythmias (VTs), triggered by acute coronary occlusion. Autonomic dysfunction, an important arrhythmogenic mechanism in this setting, is being actively investigated, aiming at the advent of preventive strategies. Recent...

Showing 1 to 12 of 25 entries