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Showing 1 to 12 of 98 entries
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Probabilistic and multiple regression modeling of the biologist's decision processes and its implications for medical diagnosis.

The Bulletin of mathematical biophysics

Keeley SM, Doherty ME.
PMID: 5158938
Bull Math Biophys. 1971 Sep;33(3):439-49. doi: 10.1007/BF02476785.

No abstract available.

Diseases of the eye.

Annual review of medicine

LEOPOLD IH, KEENEY AH.
PMID: 13092836
Annu Rev Med. 1952;3:215-30. doi: 10.1146/annurev.me.03.020152.001243.

No abstract available.

South American ophthalmology re-examined.

American journal of ophthalmology

TOWNES CD, KEENEY AH.
PMID: 13777774
Am J Ophthalmol. 1961 Jul;52:95-101.

No abstract available.

A Genetics Laboratory Module Involving Selection and Identification of Lysine Synthesis Mutants in the Yeast Saccharomyces cerevisiae.

Microbiology education

Keeney JB, Reed R.
PMID: 23653536
Microbiol Educ. 2000 May;1:26-30. doi: 10.1128/me.1.1.26-30.2000.

We have developed a laboratory exercise, currently being used with college sophomores, which uses the yeast Saccharomyces cerevisiae to convey the concepts of amino acid biosynthesis, mutation, and gene complementation. In brief, selective medium is used to isolate yeast...

The joy of six: how to control your crossovers.

Cell

Globus ST, Keeney S.
PMID: 22464316
Cell. 2012 Mar 30;149(1):11-2. doi: 10.1016/j.cell.2012.03.011.

Meiotic cells tightly regulate the number and distribution of crossovers to promote accurate chromosome segregation. Yokoo and colleagues uncover a metazoan-specific, cyclin-like protein that is crucial for crossover formation. They utilize this protein's unique properties to explore a remarkable...

Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis.

Genome dynamics and stability

Keeney S.
PMID: 21927624
Genome Dyn Stab. 2008 Jan 01;2:81-123. doi: 10.1007/7050_2007_026.

Meiotic recombination is carried out through a specialized pathway for the formation and repair of DNA double-strand breaks made by the Spo11 protein, a relative of archaeal topoisomerase VI. This review summarizes recent studies that provide insight to the...

Management of the axilla in metaplastic breast carcinoma.

Gland surgery

Murphy BL, Fazzio RT, Hoskin TL, Glazebrook KN, Keeney MG, Habermann EB, Hieken TJ.
PMID: 29770313
Gland Surg. 2018 Apr;7(2):200-206. doi: 10.21037/gs.2018.01.01.

BACKGROUND: Metaplastic breast cancer (MBC), characterized by admixed epithelial, squamous or mesenchymal elements, constitutes

The Diverse Contributions of Fucose Linkages in Cancer.

Cancers

Keeley TS, Yang S, Lau E.
PMID: 31450600
Cancers (Basel). 2019 Aug 24;11(9). doi: 10.3390/cancers11091241.

Fucosylation is a post-translational modification of glycans, proteins, and lipids that is responsible for many biological processes. Fucose conjugation via α(1,2), α(1,3), α(1,4), α(1,6), and O'- linkages to glycans, and variations in fucosylation linkages, has important implications for cancer...

A Case of Gastric Metastatic Melanoma 15 Years after the Initial Diagnosis of Cutaneous Melanoma.

Case reports in gastrointestinal medicine

Farshad S, Keeney S, Halalau A, Ghaith G.
PMID: 30151286
Case Rep Gastrointest Med. 2018 Jul 29;2018:7684964. doi: 10.1155/2018/7684964. eCollection 2018.

Melanoma is the most common cancer to metastasize to the gastrointestinal tract; however, metastasis to the stomach is a rare occurrence. We present the case of a patient with a history of melanoma of the chest wall 15 years...

Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR.

Oncotarget

Gill SE, Zhang Q, Keeney GL, Cliby WA, Weroha SJ.
PMID: 29156714
Oncotarget. 2017 Jul 27;8(49):85214-85223. doi: 10.18632/oncotarget.19620. eCollection 2017 Oct 17.

MISIIR is a potential target for ovarian cancer (OC) therapy due to its tissue-specific pattern of expression. 3C23K is a novel therapeutic monoclonal anti-MISIIR antibody designed to recruit effector cells and promote cell death through ADCC (antibody dependent cell-mediated...

George M. Farrow, MD: A Tribute.

The American journal of surgical pathology

Cheville JC, Keeney GL, Gaffey TA.
PMID: 30747783
Am J Surg Pathol. 2019 Mar;43(3):432-433. doi: 10.1097/PAS.0000000000000942.

No abstract available.

Computed structures of core eukaryotic protein complexes.

Science (New York, N.Y.)

Humphreys IR, Pei J, Baek M, Krishnakumar A, Anishchenko I, Ovchinnikov S, Zhang J, Ness TJ, Banjade S, Bagde SR, Stancheva VG, Li XH, Liu K, Zheng Z, Barrero DJ, Roy U, Kuper J, Fernández IS, Szakal B, Branzei D, Rizo J, Kisker C, Greene EC, Biggins S, Keeney S, Miller EA, Fromme JC, Hendrickson TL, Cong Q, Baker D.
PMID: 34762488
Science. 2021 Dec 10;374(6573):eabm4805. doi: 10.1126/science.abm4805. Epub 2021 Dec 10.

[Figure: see text].

Showing 1 to 12 of 98 entries