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Showing 1 to 12 of 450 entries
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Coexistence of adenomyosis uteri and endometrial cancer is associated with an improved prognosis compared with endometrial cancer only.

Oncology letters

Hertlein L, Rath J, Zeder-Göss C, Fürst S, Bayer D, Trillsch F, Mahner S, Burges A, Jeschke U.
PMID: 28927080
Oncol Lett. 2017 Sep;14(3):3302-3308. doi: 10.3892/ol.2017.6592. Epub 2017 Jul 18.

The present study aimed to identify differences in protein expression in cases of endometrioid endometrial cancer (EEC) with and without coexisting adenomyosis uteri (AM), and to evaluate the histopathological and prognostic distinctions. The total cohort included 22 patients in...

Changes in the Microenvironment of Nitroxide Radicals around the Glass Transition Temperature.

The journal of physical chemistry. B

Bordignon E, Nalepa AI, Savitsky A, Braun L, Jeschke G.
PMID: 26266707
J Phys Chem B. 2015 Oct 29;119(43):13797-806. doi: 10.1021/acs.jpcb.5b04104. Epub 2015 Aug 20.

For structural characterization by pulsed EPR methods, spin-labeled macromolecules are routinely studied at cryogenic temperatures. The equilibration of the conformational ensemble during shock-freezing occurs to a good approximation at the glass transition temperature (Tg). In this work, we used...

Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity.

Journal of clinical and translational research

Xie Y, Woolbright BL, Kos M, McGill MR, Dorko K, Kumer SC, Schmitt TM, Jaeschke H.
PMID: 26722668
J Clin Transl Res. 2015;1(2):100-106. doi: 10.18053/jctres.201502.004. Epub 2015 Sep 30.

BACKGROUND: Acetaminophen (APAP) hepatotoxicity is a major cause of acute liver failure in many countries. Mechanistic studies in mice and humans have implicated formation of a reactive metabolite, mitochondrial dysfunction and oxidant stress as critical events in the pathophysiology...

Copper ESEEM and HYSCORE through ultra-wideband chirp EPR spectroscopy.

The Journal of chemical physics

Segawa TF, Doll A, Pribitzer S, Jeschke G.
PMID: 26233121
J Chem Phys. 2015 Jul 28;143(4):044201. doi: 10.1063/1.4927088.

The main limitation of pulse electron paramagnetic resonance (EPR) spectroscopy is its narrow excitation bandwidth. Ultra-wideband (UWB) excitation with frequency-swept chirp pulses over several hundreds of megahertz overcomes this drawback. This allows to excite electron spin echo envelope modulation...

Unraveling the Origin of Magnetism in Mesoporous Cu-Doped SnO₂ Magnetic Semiconductors.

Nanomaterials (Basel, Switzerland)

Fan J, Menéndez E, Guerrero M, Quintana A, Weschke E, Pellicer E, Sort J.
PMID: 29068367
Nanomaterials (Basel). 2017 Oct 25;7(11). doi: 10.3390/nano7110348.

The origin of magnetism in wide-gap semiconductors doped with non-ferromagnetic 3d transition metals still remains intriguing. In this article, insights in the magnetic properties of ordered mesoporous Cu-doped SnO₂ powders, prepared by hard-templating, have been unraveled. Whereas, both oxygen...

The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis.

Obesity science & practice

Kalani A, Bami H, Tiboni M, Jaeschke R, Adachi JD, Lau AN.
PMID: 29071108
Obes Sci Pract. 2017 Jun 27;3(3):319-332. doi: 10.1002/osp4.113. eCollection 2017 Sep.

BACKGROUND: Concerns have emerged about post-operative decreases in calcium and vitamin D following bariatric surgery. This review explores changes in metabolic bone health in persons with obesity undergoing gastric bypass surgery compared to non-surgical controls, providing an updated and...

Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.

Journal of clinical and translational research

Ramachandran A, Jaeschke H.
PMID: 28670625
J Clin Transl Res. 2017 Feb;3:157-169. doi: 10.18053/jctres.03.2017S1.002. Epub 2017 Feb 12.

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely...

Characterization of Protein Conformational Changes with Sparse Spin-Label Distance Constraints.

Journal of chemical theory and computation

Jeschke G.
PMID: 26593026
J Chem Theory Comput. 2012 Oct 09;8(10):3854-63. doi: 10.1021/ct300113z. Epub 2012 May 03.

The combination of site-directed spin labeling with pulse EPR distance measurements can provide a moderate number of distance constraints on the nanometer length scale for proteins in different states. By adapting an existing algorithm (Zheng, W.; Brooks, B. R....

Detection of Circulating Tumour Cells from Blood of Breast Cancer Patients via RT-qPCR.

Cancers

Andergassen U, Kölbl AC, Hutter S, Friese K, Jeschke U.
PMID: 24202442
Cancers (Basel). 2013 Sep 25;5(4):1212-20. doi: 10.3390/cancers5041212.

Breast cancer is still the most frequent cause of cancer-related death in women worldwide. Often death is not caused only by the primary tumour itself, but also by metastatic lesions. Today it is largely accepted, that these remote metastases...

Artefact suppression in 5-pulse double electron electron resonance for distance distribution measurements.

Physical chemistry chemical physics : PCCP

Breitgoff FD, Soetbeer J, Doll A, Jeschke G, Polyhach YO.
PMID: 28590496
Phys Chem Chem Phys. 2017 Jun 21;19(24):15766-15779. doi: 10.1039/c7cp01488k.

A 5-pulse version of the Double Electron Electron Resonance (DEER) experiment with Carr-Purcell delays and an additional pump pulse has been shown to significantly extend the experimentally accessible distance range in cases where nuclear spin diffusion dominates electron spin...

Large-Scale Point-Cloud Visualization through Localized Textured Surface Reconstruction.

IEEE transactions on visualization and computer graphics

Arikan M, Preiner R, Scheiblauer C, Jeschke S, Wimmer M.
PMID: 26357377
IEEE Trans Vis Comput Graph. 2014 Sep;20(9):1280-92. doi: 10.1109/TVCG.2014.2312011.

In this paper, we introduce a novel scene representation for the visualization of large-scale point clouds accompanied by a set of high-resolution photographs. Many real-world applications deal with very densely sampled point-cloud data, which are augmented with photographs that...

Nonmagnetic band gap at the Dirac point of the magnetic topological insulator (Bi(1-x)Mn(x))2Se3.

Nature communications

Sánchez-Barriga J, Varykhalov A, Springholz G, Steiner H, Kirchschlager R, Bauer G, Caha O, Schierle E, Weschke E, Ünal AA, Valencia S, Dunst M, Braun J, Ebert H, Minár J, Golias E, Yashina LV, Ney A, Holý V, Rader O.
PMID: 26892831
Nat Commun. 2016 Feb 19;7:10559. doi: 10.1038/ncomms10559.

Magnetic doping is expected to open a band gap at the Dirac point of topological insulators by breaking time-reversal symmetry and to enable novel topological phases. Epitaxial (Bi(1-x)Mn(x))2Se3 is a prototypical magnetic topological insulator with a pronounced surface band...

Showing 1 to 12 of 450 entries