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Showing 1 to 12 of 42 entries
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Absorption in high-z targets illuminated with 527-nm laser light at high intensity using induced spatial incoherence.

Applied optics

Simpson JD, Bosch RA, Failor BH, Gabl EF.
PMID: 20577408
Appl Opt. 1990 Oct 20;29(30):4447-52. doi: 10.1364/AO.29.004447.

We have measured 527-nm absorption for induced spatial incoherence (ISI) and non-ISI illumination of high-Z targets over the 0.5-3.5 x 10(14)-W/cm(2) laser intensity range using energy balance with a custom designed 30-cm diam light integrating sphere. Induced spatial incoherence...

Engineered Polymeric Materials for Biological Applications: Overcoming Challenges of the Bio-Nano Interface.

Polymers

Simpson JD, Smith SA, Thurecht KJ, Such G.
PMID: 31480780
Polymers (Basel). 2019 Sep 02;11(9). doi: 10.3390/polym11091441.

Nanomedicine has generated significant interest as an alternative to conventional cancertherapy due to the ability for nanoparticles to tune cargo release. However, while nanoparticletechnology has promised significant benefit, there are still limited examples of nanoparticles inclinical practice. The low...

Anticipating ankle inversion perturbations during a single-leg drop landing alters ankle joint and impact kinetics.

Human movement science

Simpson JD, Stewart EM, Rendos NK, Cosio-Lima L, Wilson SJ, Macias DM, Chander H, Knight AC.
PMID: 30908960
Hum Mov Sci. 2019 Mar 22;66:22-30. doi: 10.1016/j.humov.2019.03.015. Epub 2019 Mar 22.

Anticipatory responses to inversion perturbations can prevent an accurate assessment of lateral ankle sprain mechanics when using injury simulations. Despite recent evidence of the anticipatory motor control strategies utilized during inversion perturbations, kinetic compensations during anticipated inversion perturbations are...

Feasibility of a mHealth Approach to Nutrition Counseling in an Appalachian State.

Journal of personalized medicine

Olfert MD, Barr ML, Hagedorn RL, Long DM, Haggerty TS, Weimer M, Golden J, Maurer MA, Cochran JD, Hendershot T, Whanger SL, Mason JD, Hodder SL.
PMID: 31757057
J Pers Med. 2019 Nov 20;9(4). doi: 10.3390/jpm9040050.

West Virginia is a rural state with an aging population that may experience barriers to accessing nutritional and lifestyle counseling. This study examined feasibility of an online personalized nutrition tracking application, Good Measures (GM), with patients at seven health...

A synthetic antibiotic class overcoming bacterial multidrug resistance.

Nature

Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G, Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS, Polikanov YS, Myers AG.
PMID: 34707295
Nature. 2021 Nov;599(7885):507-512. doi: 10.1038/s41586-021-04045-6. Epub 2021 Oct 27.

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern

Haemolytic Disease of the Newborn: Treatment with Rh-negative Blood.

British medical journal

Gimson JD.
PMID: 20785011
Br Med J. 1943 Sep 04;2(4313):293-7. doi: 10.1136/bmj.2.4313.293.

No abstract available.

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery.

Chemical science

Ediriweera GR, Simpson JD, Fuchs AV, Venkatachalam TK, Van De Walle M, Howard CB, Mahler SM, Blinco JP, Fletcher NL, Houston ZH, Bell CA, Thurecht KJ.
PMID: 34122834
Chem Sci. 2020 Mar 06;11(12):3268-3280. doi: 10.1039/d0sc00078g.

There remain several key challenges to existing therapeutic systems for cancer therapy, such as quantitatively determining the true, tissue-specific drug release profile

A synthetic antibiotic class overcoming bacterial multidrug resistance.

Nature

Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G, Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS, Polikanov YS, Myers AG.
PMID: 34707295
Nature. 2021 Nov;599(7885):507-512. doi: 10.1038/s41586-021-04045-6. Epub 2021 Oct 27.

The dearth of new medicines effective against antibiotic-resistant bacteria presents a growing global public health concern

Cyanine-5-Driven Behaviours of Hyperbranched Polymers Designed for Therapeutic Delivery Are Cell-Type Specific and Correlated with Polar Lipid Distribution in Membranes.

Nanomaterials (Basel, Switzerland)

Simpson JD, Currin-Ross DL, Ediriweera GR, Schirra HJ, Fletcher NL, Bell CA, Arno MC, Thurecht KJ.
PMID: 34361131
Nanomaterials (Basel). 2021 Jul 02;11(7). doi: 10.3390/nano11071745.

The ability to predict the behaviour of polymeric nanomedicines can often be obfuscated by subtle modifications to the corona structure, such as incorporation of fluorophores or other entities. However, these interactions provide an intriguing insight into how selection of...

Role of the Redox State of Human Peroxiredoxin-5 on Its TLR4-Activating DAMP Function.

Antioxidants (Basel, Switzerland)

Poncin MA, Van Meerbeeck P, Simpson JD, Clippe A, Tyckaert F, Bouillenne F, Degand H, Matagne A, Morsomme P, Knoops B, Alsteens D.
PMID: 34943005
Antioxidants (Basel). 2021 Nov 27;10(12). doi: 10.3390/antiox10121902.

Human peroxiredoxin-5 (PRDX5) is a unique redox-sensitive protein that plays a dual role in brain ischemia-reperfusion injury. While intracellular PRDX5 has been reported to act as a neuroprotective antioxidative enzyme by scavenging peroxides, once released extracellularly from necrotic brain...

Ultraviolet (250-550  nm) absorption spectrum of pure water.

Applied optics

Mason JD, Cone MT, Fry ES.
PMID: 27607297
Appl Opt. 2016 Sep 01;55(25):7163-72. doi: 10.1364/AO.55.007163.

Data for the spectral light absorption of pure water from 250 to 550 nm have been obtained using an integrating cavity made from a newly developed diffuse reflector with a very high UV reflectivity. The data provide the first...

It Cannot Happen, Never: A Qualitative Study Exploring Youth Views on Disclosure of HIV Diagnosis to Their Sexual Partners in Southern Malawi.

The Journal of the Association of Nurses in AIDS Care : JANAC

Zgambo M, Arabiat D, Ireson D.
PMID: 33481465
J Assoc Nurses AIDS Care. 2021 Jan 20; doi: 10.1097/JNC.0000000000000238. Epub 2021 Jan 20.

ABSTRACT: With the availability of antiretroviral therapy, more children living with HIV live longer than before and grow into young adulthood. This study examined the concerns of youth about disclosure of an HIV diagnosis to their sexual partners and...

Showing 1 to 12 of 42 entries