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Showing 1 to 12 of 23 entries
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Cytokines in the blood and semen of infertile patients.

Central-European journal of immunology

Havrylyuk A, Chopyak V, Boyko Y, Kril I, Kurpisz M.
PMID: 26648778
Cent Eur J Immunol. 2015;40(3):337-44. doi: 10.5114/ceji.2015.54596. Epub 2015 Oct 15.

Cytokines have been important mediators of the immunity and can be involved in numerous processes in the male genital tract including acting as immunomodulatory elements within the male gonad. The aims of this study were: 1) to detect pro-...

Ru(ii) complexes with diazine ligands: electronic modulation of the coordinating group is key to the design of "dual action" photoactivated agents.

Chemical communications (Cambridge, England)

Havrylyuk D, Deshpande M, Parkin S, Glazer EC.
PMID: 30338772
Chem Commun (Camb). 2018 Nov 01;54(88):12487-12490. doi: 10.1039/c8cc05809a.

Coordination complexes can be used to photocage biologically active ligands, providing control over the location, time, and dose of a delivered drug. Dual action agents can be created if both the ligand released and the ligand-deficient metal center effect...

Photochemical Properties and Structure-Activity Relationships of Ru.

European journal of inorganic chemistry

Havrylyuk D, Heidary DK, Nease L, Parkin S, Glazer EC.
PMID: 29200939
Eur J Inorg Chem. 2017 Mar 27;2017(12):1687-1694. doi: 10.1002/ejic.201601450. Epub 2017 Feb 15.

Ruthenium complexes capable of light-triggered cytotoxicity are appealing potential prodrugs for photodynamic therapy (PDT) and photoactivated chemotherapy (PACT). Two groups of Ru(II) polypyridyl complexes with 2-(2-pyridyl)-benzazole ligands were synthesized and investigated for their photochemical properties and anticancer activity to...

Photochemical and Photobiological Properties of Pyridyl-pyrazol(in)e-Based Ruthenium(II) Complexes with Sub-micromolar Cytotoxicity for Phototherapy.

ACS omega

Havrylyuk D, Heidary DK, Sun Y, Parkin S, Glazer EC.
PMID: 32775891
ACS Omega. 2020 Jul 23;5(30):18894-18906. doi: 10.1021/acsomega.0c02079. eCollection 2020 Aug 04.

The discovery of new light-triggered prodrugs based on ruthenium (II) complexes is a promising approach for photoactivated chemotherapy (PACT). The light-mediated activation of "strained" Ru(II) polypyridyl complexes resulted in ligand release and produced a ligand-deficient metal center capable of...

Colloidal Cu-Zn-Sn-Te Nanocrystals: Aqueous Synthesis and Raman Spectroscopy Study.

Nanomaterials (Basel, Switzerland)

Dzhagan V, Kapush O, Mazur N, Havryliuk Y, Danylenko MI, Budzulyak S, Yukhymchuk V, Valakh M, Litvinchuk AP, Zahn DRT.
PMID: 34835686
Nanomaterials (Basel). 2021 Oct 31;11(11). doi: 10.3390/nano11112923.

Cu-Zn-Sn-Te (CZTTe) is an inexpensive quaternary semiconductor that has not been investigated so far, unlike its intensively studied CZTS and CZTSe counterparts, although it may potentially have desirable properties for solar energy conversion, thermoelectric, and other applications. Here, we...

Draft Genome Sequences of Six Strains Isolated from the Rhizosphere of Wheat Grown in Cadmium-Contaminated Soil.

Microbiology resource announcements

Hovorukha V, Bhattacharyya A, Iungin O, Tashyreva H, Romanovska V, Havryliuk O, Bielikova O, Blackwell C, Burks B, Cothern C, Elliott J, Hoover J, Jones A, Leise C, Lowmiller L, Mohamed A, Mullen T, Nettleton E, Polk K, Tran B, Tran T, Vega M, Ware L, Welch E, Williams L, Woodard M, Young K, Mavrodi O, Tashyrev O, Mavrodi D.
PMID: 32816975
Microbiol Resour Announc. 2020 Aug 20;9(34). doi: 10.1128/MRA.00676-20.

This study presents high-quality draft genome assemblies of six bacterial strains isolated from the roots of wheat grown in soil contaminated with cadmium. The results of this study will help to elucidate at the molecular level how heavy metals...

Toward Optimal Ru(II) Photocages: Balancing Photochemistry, Stability, and Biocompatibility Through Fine Tuning of Steric, Electronic, and Physiochemical Features.

Inorganic chemistry

Havrylyuk D, Stevens K, Parkin S, Glazer EC.
PMID: 31899619
Inorg Chem. 2020 Jan 21;59(2):1006-1013. doi: 10.1021/acs.inorgchem.9b02065. Epub 2020 Jan 03.

Ru(II) complex photocages are used in a variety of biological applications, but the thermal stability, photosubstitution quantum yield, and biological compatibility of the most commonly used Ru(II) systems remain unoptimized. Here, multiple compounds used in photocaging applications were analyzed...

Platelet autologous plasma in post-traumatic knee osteoarthritis treatment.

Journal of clinical orthopaedics and trauma

Havryliuk H, Khimion L.
PMID: 30705530
J Clin Orthop Trauma. 2019 Jan-Feb;10(1):42-45. doi: 10.1016/j.jcot.2018.08.007. Epub 2018 Aug 06.

No abstract available.

Intramolecular Interactions Dominate the Autoregulation of .

Frontiers in microbiology

Turnbull KJ, Dzhygyr I, Lindemose S, Hauryliuk V, Roghanian M.
PMID: 31507571
Front Microbiol. 2019 Aug 27;10:1966. doi: 10.3389/fmicb.2019.01966. eCollection 2019.

Amino acid starvation in

Draft whole genome sequence for four highly copper resistant soil isolates .

Current research in microbial sciences

Havryliuk O, Hovorukha V, Patrauchan M, Youssef NH, Tashyrev O.
PMID: 34841301
Curr Res Microb Sci. 2020 Jun 27;1:44-52. doi: 10.1016/j.crmicr.2020.06.002. eCollection 2020 Sep.

Environmental copper pollution causes major destruction to ecological systems, which require the development of environmentally friendly biotechnological, in particular, microbial methods for copper removal. These methods rely on the availability of microorganisms resistant to high levels of copper. Here...

Raman and X-ray Photoelectron Spectroscopic Study of Aqueous Thiol-Capped Ag-Zn-Sn-S Nanocrystals.

Materials (Basel, Switzerland)

Dzhagan V, Selyshchev O, Havryliuk Y, Mazur N, Raievska O, Stroyuk O, Kondratenko S, Litvinchuk AP, Valakh MY, Zahn DRT.
PMID: 34199129
Materials (Basel). 2021 Jun 27;14(13). doi: 10.3390/ma14133593.

The synthesis of (Cu,Ag)-Zn-Sn-S (CAZTS) and Ag-Zn-Sn-S (AZTS) nanocrystals (NCs) by means of "green" chemistry in aqueous solution and their detailed characterization by Raman spectroscopy and several complementary techniques are reported. Through a systematic variation of the nominal composition...

Computational Search for Possible Mechanisms of 4-Thiazolidinones Anticancer Activity: The Power of Visualization.

Molecular informatics

Devinyak O, Havrylyuk D, Zimenkovsky B, Lesyk R.
PMID: 27485690
Mol Inform. 2014 Mar;33(3):216-29. doi: 10.1002/minf.201300086. Epub 2014 Mar 11.

Public databases of NCI-60 tumor cell line screen results and measurements of molecular targets in the NCI-60 panel give the opportunity to assign possible anticancer mechanism to compounds with positive outcome from antitumor assay. Here, the novel protocol of...

Showing 1 to 12 of 23 entries