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Showing 1 to 12 of 14 entries
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A polycomponent metal-catalyzed aliphatic, allylic, and benzylic fluorination.

Angewandte Chemie (International ed. in English)

Bloom S, Pitts CR, Miller DC, Haselton N, Holl MG, Urheim E, Lectka T.
PMID: 22976771
Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10580-3. doi: 10.1002/anie.201203642. Epub 2012 Sep 13.

A group effort: Reported is the title reaction using a polycomponent catalytic system involving commercially available Selectfluor, a putative radical precursor N-hydroxyphthalimide, an anionic phase-transfer catalyst (KB(C(6)F(5))(4)), and a copper(I) bis(imine). The catalyst system formed leads to monofluorinated compounds...

Pneumothorax and Pneumatocoele Formation in a Patient with COVID-19: a Case Report.

SN comprehensive clinical medicine

Capleton P, Ricketts W, Lau K, Ellis S, Sheaff M, Giaslakiotis K, Uys S, Tchrakian N.
PMID: 33432305
SN Compr Clin Med. 2021 Jan 07;1-4. doi: 10.1007/s42399-020-00689-z. Epub 2021 Jan 07.

Coronavirus disease 2019 (COVID-19) causes significant morbidity and mortality for a proportion of infected patients, and our knowledge and understanding of its clinical, radiological and histopathological features are still evolving. An association between COVID-19 and pneumothorax has been described...

Myocardial rupture and left ventricular pseudoaneurysm due to late STEMI presentation during the COVID-19 pandemic lockdown: a classical case report.

European heart journal. Case reports

Banisauskaite A, Velavan P, Hasleton J, Mediratta N, Arzanauskaite M, Binukrishnan S.
PMID: 34377907
Eur Heart J Case Rep. 2021 Jul 18;5(7):ytab253. doi: 10.1093/ehjcr/ytab253. eCollection 2021 Jul.

BACKGROUND: Left ventricular (LV) pseudoaneurysm is a serious and rare complication of myocardial infarction (MI). It occurs when an injured myocardial wall ruptures and is contained by overlying adherent pericardium or scar tissue, most commonly it develops in patients...

Interaction of a C-F bond with the π-system of a C═C bond or "head on" with a proximate C-H bond.

The Journal of organic chemistry

Scerba MT, Bloom S, Haselton N, Siegler M, Jaffe J, Lectka T.
PMID: 22283798
J Org Chem. 2012 Feb 03;77(3):1605-9. doi: 10.1021/jo2024152. Epub 2012 Jan 25.

We describe the synthesis and preliminary study of two molecules, in which a fluorine atom is positioned proximately above the π-orbitals of a C═C bond or else wherein a C-F bond interacts in a "head on" fashion with a...

Haemoptysis in pregnancy caused by a well-differentiated fetal adenocarcinoma: a case report.

Journal of medical case reports

Thompson RJ, Hasleton PS, Taylor PM, Woodhead M, Byrd LM.
PMID: 20205788
J Med Case Rep. 2010 Jan 20;4:17. doi: 10.1186/1752-1947-4-17.

INTRODUCTION: Haemoptysis in pregnancy is frequently assumed to be caused by a pulmonary embolism. However, it can also be an indicator of serious pathology.CASE PRESENTATION: We report the case of a 27-year-old Caucasian woman who presented with haemoptysis in...

Is Postpartum Depression a Disease of Modern Civilization?.

Current directions in psychological science

Hahn-Holbrook J, Haselton M.
PMID: 28503034
Curr Dir Psychol Sci. 2014 Dec;23(6):395-400. doi: 10.1177/0963721414547736. Epub 2014 Dec 16.

Access to calorie-dense foods, medicine, and other comforts has made modern humans healthier than our prehistoric ancestors in many respects. However, the epidemics of obesity, diabetes, and cardiovascular disease suggest that there are also drawbacks to modern living. Here,...

Atypical presentation of an unusual lung tumor.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology

Kaptanoglu M, Nadir A, Arici S, Hasleton P.
PMID: 17415857
J BUON. 2004 Oct-Dec;9(4):477-9.

We describe a case of a rare bronchial epithelial- myoepithelial carcinoma of the lung in a 36-year-old man. Tumor enucleation was carried out and the patient was put on long-term follow up. Tumor categorisation was difficult. The patient is...

CMR in Heart Failure.

Cardiology research and practice

Sado DM, Hasleton JM, Herrey AS, Moon JC.
PMID: 21876825
Cardiol Res Pract. 2011;2011:739157. doi: 10.4061/2011/739157. Epub 2011 Aug 16.

Heart Failure (HF) is a common syndrome with multiple causes. Cardiovascular magnetic resonance (CMR) is a medical imaging technique with significant advantages, allowing the understanding of aetiology and pathophysiology of HF in the individual patient, permitting specific therapy to...

Development and validation of IMMUNO-COV™: a high-throughput clinical assay for detecting antibodies that neutralize SARS-CoV-2.

bioRxiv : the preprint server for biology

Vandergaast R, Carey T, Reiter S, Lech P, Gnanadurai C, Tesfay M, Buehler J, Suksanpaisan L, Naik S, Brunton B, Recker J, Haselton M, Ziegler C, Roesler A, Mills JR, Theel E, Weaver SC, Rafael G, Roforth MM, Jerde C, Tran S, Diaz RM, Bexon A, Baum A, Kyratsous CA, Peng KW, Russell SJ.
PMID: 32577655
bioRxiv. 2020 May 27; doi: 10.1101/2020.05.26.117549.

We here describe the development and validation of IMMUNO-COV™, a high-throughput clinical test to quantitatively measure SARS-CoV-2-neutralizing antibodies, the specific subset of anti-SARS-CoV-2 antibodies that block viral infection. The test measures the capacity of serum or purified antibodies to...

Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial.

Clinical journal of the American Society of Nephrology : CJASN

Frishberg Y, Deschênes G, Groothoff JW, Hulton SA, Magen D, Harambat J, Van't Hoff WG, Lorch U, Milliner DS, Lieske JC, Haslett P, Garg PP, Vaishnaw AK, Talamudupula S, Lu J, Habtemariam BA, Erbe DV, McGregor TL, Cochat P.
PMID: 33985991
Clin J Am Soc Nephrol. 2021 Jul;16(7):1025-1036. doi: 10.2215/CJN.14730920. Epub 2021 May 13.

BACKGROUND AND OBJECTIVES: In the rare disease primary hyperoxaluria type 1, overproduction of oxalate by the liver causes kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis. Lumasiran, an RNA interference therapeutic, suppresses glycolate oxidase, reducing hepatic oxalate production. The...

On Ramsey and star-critical Ramsey numbers for generalized fans versus .

Discrete applied mathematics (Amsterdam, Netherlands : 1988)

Hamm A, Hazelton P, Thompson S.
PMID: 34898765
Discrete Appl Math. 2021 Dec 31;305:64-70. doi: 10.1016/j.dam.2021.08.027. Epub 2021 Sep 09.

In this paper, we determine the Ramsey number and star-critical Ramsey number, under certain restrictions on the relevant parameters, for

Cardiac Computed Tomography to Identify and Guide Therapy of Intramural Hemorrhage in High-Risk Coronary Anatomy.

JACC. Case reports

Jatti K, Maurovich-Horvat P, Hasleton J, Uddin M, Ruzsics B.
PMID: 34317483
JACC Case Rep. 2021 Jan 20;3(1):120-124. doi: 10.1016/j.jaccas.2020.11.014. eCollection 2021 Jan.

Coronary intramural hematoma can present with acute coronary syndrome. We present a 39-year-old man with post-assault stress-induced left main intramural hematoma. We used computed tomography coronary angiogram with lesion characterization and suspected the diagnosis of intramural hematoma despite its...

Showing 1 to 12 of 14 entries