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Purification of myocardial adenosine kinase using affinity and ion-exchange chromatography.

Advances in experimental medicine and biology

Uitendaal MP, De Jong JW, Harmsen E, Keijzer E.
PMID: 232640
Adv Exp Med Biol. 1979;122:409-14. doi: 10.1007/978-1-4684-8559-2_65.

No abstract available.

Nuclear magnetic resonance studies of cellular metabolism.

Analytical biochemistry

Lundberg P, Harmsen E, Ho C, Vogel HJ.
PMID: 2085167
Anal Biochem. 1990 Dec;191(2):193-222. doi: 10.1016/0003-2697(90)90210-z.

No abstract available.

Combined use of radioenzymatic assay and high pressure liquid chromatography for the detection of myocardial xanthine oxidase/dehydrogenase.

Advances in experimental medicine and biology

Schoutsen B, de Tombe P, Harmsen E, Keijzer E, de Jong JW.
PMID: 6372386
Adv Exp Med Biol. 1984;165:497-500. doi: 10.1007/978-1-4757-0390-0_94.

No abstract available.

Myocardial release of hypoxanthine and lactate during percutaneous transluminal coronary angioplasty.

The American journal of cardiology

Serruys PW, Suryapranata H, Piscione F, Harmsen E, van den Brand M, de Feyter P, Hugenholtz PG, de Jong JW.
PMID: 2522269
Am J Cardiol. 1989 Mar 07;63(10):45E-51E. doi: 10.1016/0002-9149(89)90230-0.

The response of myocardial lactate and hypoxanthine metabolism during percutaneous transluminal coronary angioplasty was studied in a series of 15 patients undergoing this procedure. A minimum of 4 balloon inflations was performed per patient with an average duration per...

Dietary sodium and Na,K-ATPase activity in Dahl salt-sensitive versus salt-resistant rats.

Journal of hypertension

Abdelrahman AM, Harmsen E, Leenen FH.
PMID: 7561008
J Hypertens. 1995 May;13(5):517-22. doi: 10.1097/00004872-199505000-00006.

OBJECTIVE: To investigate the effects of high dietary sodium on brain and kidney Na,K-ATPase activity in Dahl salt-sensitive (Dahl-S) and salt-resistant (Dahl-R) rats.METHODS: From the age of 4 weeks Dahl-S and Dahl-R rats were fed either standard or high-sodium...

Inosine incorporation into adenine- and guanine nucleotides in the isolated perfused rat heart is stimulated after ischemia.

Advances in experimental medicine and biology

Harmsen E, de Tombe P, Achterberg P, de Jong JW.
PMID: 6720448
Adv Exp Med Biol. 1984;165:487-90. doi: 10.1007/978-1-4757-0390-0_92.

No abstract available.

Balance of purine nucleotides and catabolites in the isolated ischemic rat heart.

Advances in experimental medicine and biology

Achterberg PW, Harmsen E, de Tombe PP, de Jong JW.
PMID: 6720447
Adv Exp Med Biol. 1984;165:483-6. doi: 10.1007/978-1-4757-0390-0_91.

No abstract available.

Further purification of adenosine kinase from rat heart using affinity and ion-exchange chromatography.

Analytical biochemistry

de Jong JW, Keijzer E, Uitendaal MP, Harmsen E.
PMID: 6244758
Anal Biochem. 1980 Jan 15;101(2):407-12. doi: 10.1016/0003-2697(80)90206-7.

No abstract available.

Improved high-performance liquid chromatographic method in the analysis of adenovirus particles.

Journal of chromatography. B, Biomedical sciences and applications

Klyushnichenko V, Bernier A, Kamen A, Harmsen E.
PMID: 11393714
J Chromatogr B Biomed Sci Appl. 2001 May 05;755(1):27-36. doi: 10.1016/s0378-4347(00)00597-1.

We developed a HPLC method on a novel continuous bed matrix (UNO Q, Bio-Rad) for the direct quantification of adenoviral type 5 (Ad5) particles produced in 293S Human Embryonic Kidney cells and compared this with an existing HPLC method...

Genome-wide search for exonic variants affecting translational efficiency.

Nature communications

Li Q, Makri A, Lu Y, Marchand L, Grabs R, Rousseau M, Ounissi-Benkalha H, Pelletier J, Robert F, Harmsen E, Hudson TJ, Pastinen T, Polychronakos C, Qu HQ.
PMID: 23900168
Nat Commun. 2013;4:2260. doi: 10.1038/ncomms3260.

The search for expression quantitative trait loci has traditionally centred entirely on the process of transcription, whereas variants with effects on messenger RNA translation have not been systematically studied. Here we present a high-throughput approach for measuring translational cis-regulation...

A survey of genetic and epigenetic variation affecting human gene expression.

Physiological genomics

Pastinen T, Sladek R, Gurd S, Sammak A, Ge B, Lepage P, Lavergne K, Villeneuve A, Gaudin T, Brändström H, Beck A, Verner A, Kingsley J, Harmsen E, Labuda D, Morgan K, Vohl MC, Naumova AK, Sinnett D, Hudson TJ.
PMID: 14583597
Physiol Genomics. 2004 Jan 15;16(2):184-93. doi: 10.1152/physiolgenomics.00163.2003.

The identification of human sequence polymorphisms that regulate gene expression is key to understanding human genetic diseases. We report a survey of human genes that demonstrate allelic differences in gene expression, reflecting the presence of putative allele-specific cis-acting factors...

A cis-acting regulatory variant in the IL2RA locus.

Journal of immunology (Baltimore, Md. : 1950)

Qu HQ, Verlaan DJ, Ge B, Lu Y, Lam KC, Grabs R, Harmsen E, Hudson TJ, Hakonarson H, Pastinen T, Polychronakos C.
PMID: 19794070
J Immunol. 2009 Oct 15;183(8):5158-62. doi: 10.4049/jimmunol.0901337. Epub 2009 Sep 30.

The mechanism for the association of type 1 diabetes (T1D) with IL2RA remains to be clarified. Neither of the two distinct, transmission-disequilibrium confirmed loci mapping to this gene can be explained by a coding variant. An effect on the...

Showing 1 to 12 of 58 entries