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Showing 1 to 12 of 18 entries
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Nitrogen Fixation and Carbon Dioxide Assimilation in Rhizobium japonicum.

Applied and environmental microbiology

Manian SS, Gumbleton R, Buckley AM, O'gara F.
PMID: 16346608
Appl Environ Microbiol. 1984 Aug;48(2):276-9. doi: 10.1128/aem.48.2.276-279.1984.

In free-living Rhizobium japonicum cultures, the stimulatory effect of CO(2) on nitrogenase (acetylene reduction) activity was mediated through ribulose bisphosphate carboxylase activity. Two mutant strains (CJ5 and CJ6) of R. japonicum defective in CO(2) fixation were isolated by mitomycin...

Oxidation and RGD Modification Affect the Early Neural Differentiation of Murine Embryonic Stem Cells Cultured in Core-Shell Alginate Hydrogel Microcapsules.

Cells, tissues, organs

Dumbleton J, Shamul JG, Jiang B, Agarwal P, Huang H, Jia X, He X.
PMID: 34038907
Cells Tissues Organs. 2021 May 26;1-10. doi: 10.1159/000514580. Epub 2021 May 26.

Directed neural differentiation of embryonic stem cells (ESCs) has been studied extensively to improve the treatment of neurodegenerative disorders. This can be done through stromal-cell derived inducing activity (SDIA), by culturing ESCs directly on top of a layer of...

Modulation of the fate of zein nanoparticles by their coating with a Gantrez® AN-thiamine polymer conjugate.

International journal of pharmaceutics: X

Inchaurraga L, Martínez-López AL, Abdulkarim M, Gumbleton M, Quincoces G, Peñuelas I, Martin-Arbella N, Irache JM.
PMID: 31517271
Int J Pharm X. 2019 Jan 25;1:100006. doi: 10.1016/j.ijpx.2019.100006. eCollection 2019 Dec.

The aim of this work was to evaluate the mucus-permeating properties of nanocarriers using zein nanoparticles (NPZ) coated with a Gantrez® AN-thiamine conjugate (GT). NPZ were coated by incubation at different GT-to-zein ratios: 2.5% coating with GT (GT-NPZ1), 5%...

A Biomimetic Core-Shell Platform for Miniaturized 3D Cell and Tissue Engineering.

Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems

Agarwal P, Choi JK, Huang H, Zhao S, Dumbleton J, Li J, He X.
PMID: 26457002
Part Part Syst Charact. 2015 Aug;32(8):809-816. doi: 10.1002/ppsc.201500025. Epub 2015 May 12.

No abstract available.

Adverse events with silicone hydrogel continuous wear.

Contact lens & anterior eye : the journal of the British Contact Lens Association

Dumbleton K.
PMID: 16303486
Cont Lens Anterior Eye. 2002 Sep;25(3):137-46. doi: 10.1016/s1367-0484(02)00009-7.

High Dk silicone hydrogel lenses have overcome many of the hypoxic problems associated with traditional extended wear and the popularity of continuous wear (up to 30 nights) with these lens types is increasing. Results from clinical trials indicate that...

Cancers

Civita P, Valerio O, Naccarato AG, Gumbleton M, Pilkington GJ.
PMID: 33322379
Cancers (Basel). 2020 Dec 11;12(12). doi: 10.3390/cancers12123720.

The secondary structures of Scherer commonly known as perineuronal and perivascular satellitosis have been identified as a histopathological hallmark of diffuse, invasive, high-grade gliomas. They are recognised as perineuronal satellitosis when clusters of neoplastic glial cells surround neurons cell...

Caveolin-1, a Key Mediator Across Multiple Pathways in Glioblastoma and an Independent Negative Biomarker of Patient Survival.

Frontiers in oncology

Moriconi C, Civita P, Neto C, Pilkington GJ, Gumbleton M.
PMID: 34490102
Front Oncol. 2021 Aug 20;11:701933. doi: 10.3389/fonc.2021.701933. eCollection 2021.

Glioblastoma (GB) remains an aggressive malignancy with an extremely poor prognosis. Discovering new candidate drug targets for GB remains an unmet medical need. Caveolin-1 (Cav-1) has been shown to act variously as both a tumour suppressor and tumour promoter...

Humidified Warmed CO.

Frontiers in medicine

El-Betany AMM, Behiry EM, Gumbleton M, Harding KG.
PMID: 33425942
Front Med (Lausanne). 2020 Dec 11;7:594295. doi: 10.3389/fmed.2020.594295. eCollection 2020.

The coronavirus disease (COVID-19) outbreak has presented enormous challenges for healthcare, societal, and economic systems worldwide. There is an urgent global need for a universal vaccine to cover all SARS-CoV-2 mutant strains to stop the current COVID-19 pandemic and...

Role of inositol phospholipid signaling in natural killer cell biology.

Frontiers in immunology

Gumbleton M, Kerr WG.
PMID: 23508471
Front Immunol. 2013 Mar 06;4:47. doi: 10.3389/fimmu.2013.00047. eCollection 2013.

Natural killer (NK) cells are important for host defense against malignancy and infection. At a cellular level NK cells are activated when signals from activating receptors exceed signaling from inhibitory receptors. At a molecular level NK cells undergo an...

SHIPi Enhances Autologous and Allogeneic Hematolymphoid Stem Cell Transplantation.

EBioMedicine

Fernandes S, Brooks R, Gumbleton M, Park MY, Russo CM, Howard KT, Chisholm JD, Kerr WG.
PMID: 26052545
EBioMedicine. 2015 Mar 01;2(3):205-213. doi: 10.1016/j.ebiom.2015.02.004.

Hematopoietic stem cell transplantation (HSCT) is a highly effective procedure enabling long-term survival for patients with hematologic malignancy or heritable defects. Although there has been a dramatic increase in the success rate of HSCT over the last two decades,...

Oral Immunogenicity in Mice and Sows of Enterotoxigenic Escherichia Coli Outer-Membrane Vesicles Incorporated into Zein-Based Nanoparticles.

Vaccines

Matías J, Brotons A, Cenoz S, Pérez I, Abdulkarim M, Gumbleton M, Irache JM, Gamazo C.
PMID: 31906120
Vaccines (Basel). 2019 Dec 31;8(1). doi: 10.3390/vaccines8010011.

Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of illness and death in neonatal and recently weaned pigs. The immune protection of the piglets derives from maternal colostrum, since this species does not receive maternal antibodies through the...

Corrigendum to "Quantification of contact lens wettability after prolonged visual device use under low humidity conditions" [Cont. Lens Anterior Eye 42 (2019) 386-391].

Contact lens & anterior eye : the journal of the British Contact Lens Association

Guillon M, Dumbleton K, Patel T, Patel K, Gupta R, Maissa CA.
PMID: 31836204
Cont Lens Anterior Eye. 2020 Feb;43(1):91. doi: 10.1016/j.clae.2019.12.004. Epub 2019 Dec 10.

No abstract available.

Showing 1 to 12 of 18 entries