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Showing 1 to 12 of 28 entries
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Assessing quality standards for ChIP-seq and related massive parallel sequencing-generated datasets: When rating goes beyond avoiding the crisis.

Genomics data

Mendoza-Parra MA, Gronemeyer H.
PMID: 26484107
Genom Data. 2014 Aug 14;2:268-73. doi: 10.1016/j.gdata.2014.08.002. eCollection 2014 Dec.

Massive parallel DNA sequencing combined with chromatin immunoprecipitation and a large variety of DNA/RNA-enrichment methodologies is at the origin of data resources of major importance. Indeed these resources, available for multiple genomes, represent the most comprehensive catalogue of (i)...

Announcements.

Computer aided surgery : official journal of the International Society for Computer Aided Surgery

Cleary K, Anderson J, Brazaitis M, Devey G, DiGioia A, Freedman M, Gronemeyer D, Lathan C, Lemke H, Long D, Mun SK, Taylor R.
PMID: 10964091
Comput Aided Surg. 2000;5(3):216. doi: 10.1002/1097-0150(2000)5:3<216::aid-igs7>3.0.co;2-w.

No abstract available.

Discovery of novel transcriptional and epigenetic targets in APL by global ChIP analyses: Emerging opportunity and challenge.

Cancer cell

Mikesch JH, Gronemeyer H, So CW.
PMID: 20159604
Cancer Cell. 2010 Feb 17;17(2):112-4. doi: 10.1016/j.ccr.2010.01.012.

Identifying transcriptional program(s) deregulated by oncoproteins is key to understanding the molecular basis of the disease. In this issue of Cancer Cell, two studies by Martens et al. and Wang et al. provide global blueprints for transcriptional targets and...

Modeling gene-regulatory networks to describe cell fate transitions and predict master regulators.

NPJ systems biology and applications

Cholley PE, Moehlin J, Rohmer A, Zilliox V, Nicaise S, Gronemeyer H, Mendoza-Parra MA.
PMID: 30083390
NPJ Syst Biol Appl. 2018 Aug 02;4:29. doi: 10.1038/s41540-018-0066-z. eCollection 2018.

Complex organisms originate from and are maintained by the information encoded in the genome. A major challenge of systems biology is to develop algorithms that describe the dynamic regulation of genome functions from large omics datasets. Here, we describe...

Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes.

EMBO reports

Nebbioso A, Manzo F, Miceli M, Conte M, Manente L, Baldi A, De Luca A, Rotili D, Valente S, Mai A, Usiello A, Gronemeyer H, Altucci L.
PMID: 33438796
EMBO Rep. 2020 Dec 03;21(12):e51028. doi: 10.15252/embr.202051028. Epub 2020 Nov 26.

No abstract available.

INOCULATION OF MEDIA FOR MOLD CULTURE.

Science (New York, N.Y.)

Wallingford VH, Homeyer AH, Gronemeyer HB.
PMID: 17735976
Science. 1944 Mar 31;99(2570):266. doi: 10.1126/science.99.2570.266.

No abstract available.

Japanese Society for Retinoid Research--tenth symposium. 17-19 November 1999, Tokyo, Japan.

IDrugs : the investigational drugs journal

Gronemeyer H.
PMID: 16107934
IDrugs. 2000 Feb;3(2):177-8.

No abstract available.

Complexity against current cancer research - are we on the wrong track?.

International journal of cancer

Kasikci Y, Gronemeyer H.
PMID: 34921726
Int J Cancer. 2021 Dec 18; doi: 10.1002/ijc.33912. Epub 2021 Dec 18.

Cancer genetics has led to major discoveries, including proto-oncogene and tumor-suppressor concepts, and cancer genomics generated concepts like driver and passenger genes, revealed tumor heterogeneity and clonal evolution. Reconstructing trajectories of tumorigenesis using spatial and single-cell genomics is possible....

Reductionism that leads to manuscript rejection.

International journal of cancer

Gronemeyer H.
PMID: 34904719
Int J Cancer. 2021 Dec 14; doi: 10.1002/ijc.33899. Epub 2021 Dec 14.

No abstract available.

CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity.

iScience

Siouda M, Dujardin AD, Barbollat-Boutrand L, Mendoza-Parra MA, Gibert B, Ouzounova M, Bouaoud J, Tonon L, Robert M, Foy JP, Lavergne V, Manie SN, Viari A, Puisieux A, Ichim G, Gronemeyer H, Saintigny P, Mulligan P.
PMID: 32450513
iScience. 2020 Jun 26;23(6):101141. doi: 10.1016/j.isci.2020.101141. Epub 2020 May 06.

Epigenetic deregulation of gene transcription is central to cancer cell plasticity and malignant progression but remains poorly understood. We found that the uncharacterized epigenetic factor chromodomain on Y-like 2 (CDYL2) is commonly over-expressed in breast cancer, and that high...

Complexity against current cancer research: Are we on the wrong track?.

International journal of cancer

Kasikci Y, Gronemeyer H.
PMID: 34921726
Int J Cancer. 2021 Dec 18; doi: 10.1002/ijc.33912. Epub 2021 Dec 18.

Cancer genetics has led to major discoveries, including protooncogene and tumor-suppressor concepts, and cancer genomics generated concepts like driver and passenger genes, revealed tumor heterogeneity and clonal evolution. Reconstructing trajectories of tumorigenesis using spatial and single-cell genomics is possible....

[Evidence of Improved Patient Safety in Germany].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))

Bauer SH, Gronemeyer S.
PMID: 33607695
Gesundheitswesen. 2021 Feb 19; doi: 10.1055/a-1335-4813. Epub 2021 Feb 19.

Since 2015, the requirement for data transparency has been met in Germany by publishing structured quality reports in licensed hospitals, but one of the main concerns of patients, namely treatment safety, has not been a prominent feature of these...

Showing 1 to 12 of 28 entries