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Showing 1 to 12 of 19 entries
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Consensus on pathological classifications of testicular tumours.

Mostofi FK, Spaander P, Grigor K, Parkinson CM, Shakkebaek NE, Oliver RT.
PMID: 2217471
Prog Clin Biol Res. 1990;357:267-76.

No abstract available.

Interpretation of biopsies of "normal" urothelium in patients with superficial bladder cancer. MRC Superficial Bladder Cancer Sub Group.

Richards B, Parmar MK, Anderson CK, Ansell ID, Grigor K, Hall RR, Morley AR, Mostofi FK, Risdon RA, Uscinska BM.
PMID: 2032076
Br J Urol. 1991 Apr;67(4):369-75. doi: 10.1111/j.1464-410x.1991.tb15164.x.

In the course of a Medical Research Council trial of intravesical chemotherapy, biopsies were taken from apparently normal bladder urothelium near to newly diagnosed superficial bladder cancers in 417 patients. Differences were noted in the rates at which histological...

The loss of 5alpha-reductase type I and type II mRNA expression in metastatic prostate cancer to bone and lymph node metastasis.

Habib FK, Ross M, Bayne CW, Bollina P, Grigor K, Chapman K.
PMID: 12738739
Clin Cancer Res. 2003 May;9(5):1815-9.

PURPOSE: Considerable evidence has accumulated demonstrating that the 5alpha-reduction of testosterone to dihydrotestosterone occurs more efficiently in the normal and benign hyperplastic prostate than in prostate cancer tissues. Efforts have also been channeled into investigating the distribution of 5alpha-reductase...

A randomized trial of radical radiotherapy for the management of pT1G3 NXM0 transitional cell carcinoma of the bladder.

Harland SJ, Kynaston H, Grigor K, Wallace DM, Beacock C, Kockelbergh R, Clawson S, Barlow T, Parmar MK, Griffiths GO.
PMID: 17631326
J Urol. 2007 Sep;178(3):807-13; discussion 813. doi: 10.1016/j.juro.2007.05.024. Epub 2007 Jul 16.

PURPOSE: We conducted a multicenter randomized trial in the United Kingdom to determine the efficacy of radical radiotherapy in reducing the incidence of progression of pT1G3 transitional cell carcinoma of the bladder to muscle invasive disease and subsequent disease...

CD4+ and CD8+ T-lymphocyte scores cannot reliably predict progression in patients with benign prostatic hyperplasia.

Lamb AD, Qadan M, Roberts S, Timlin H, Vowler SL, Campbell FM, Grigor K, Bartlett JM, McNeill SA.
PMID: 21457430
BJU Int. 2011 Jul;108(2):E43-50. doi: 10.1111/j.1464-410X.2010.09787.x. Epub 2011 Apr 01.

OBJECTIVE: To determine whether the density of CD4(+) and CD8(+) T-lymphocytes in a transrectal ultrasonography (TRUS) biopsy of the prostate can be used to predict the progression of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH).PATIENTS AND...

HER2/neu gene amplification and protein overexpression in G3 pT2 transitional cell carcinoma of the bladder: a role for anti-HER2 therapy?.

Latif Z, Watters AD, Dunn I, Grigor K, Underwood MA, Bartlett JM.
PMID: 14687790
Eur J Cancer. 2004 Jan;40(1):56-63. doi: 10.1016/j.ejca.2003.08.027.

HER2/neu is an oncogene encoding a type 1 tyrosine kinase growth factor receptor. Polysomy 17, gene amplification and HER2/neu protein overexpression are associated with a poor prognosis in transitional cell carcinomas (TCC) of the bladder. Due to the application...

Clinicopathological role of tumour index substances in paediatric neoplasia.

Neville AM, Grigor K, Heyderman E.
PMID: 63470
J Clin Pathol. 1976 Nov;29(11):1026-32. doi: 10.1136/jcp.29.11.1026.
Free PMC Article

No abstract available.

Organization and integration sites in the human genome of endogenous retroviral sequences belonging to HERV-E family.

Taruscio D, Floridia G, Zoraqi GK, Mantovani A, Falbo V.
PMID: 11956766
Mamm Genome. 2002 Apr;13(4):216-22. doi: 10.1007/s00335-001-2118-7.

The present paper reports the characterization of HERV-E endogenous retroviral sequences in the human genome by using three complementary approaches. Firstly, we identified genomic clones containing HERV-E by BLAST screening of human DNA databases by using the entire sequence...

A UK-based investigation of inter- and intra-observer reproducibility of Gleason grading of prostatic biopsies.

Melia J, Moseley R, Ball RY, Griffiths DF, Grigor K, Harnden P, Jarmulowicz M, McWilliam LJ, Montironi R, Waller M, Moss S, Parkinson MC.
PMID: 16681679
Histopathology. 2006 May;48(6):644-54. doi: 10.1111/j.1365-2559.2006.02393.x.

AIMS: The frequency of prostatic core biopsies to detect cancer has been increasing with more widespread prostate specific antigen (PSA) testing. Gleason score has important implications for patient management but morphological reproducibility data for British practice are limited. Using...

Trends in reporting Gleason score 1991 to 2001: changes in the pathologist's practice.

Ghani KR, Grigor K, Tulloch DN, Bollina PR, McNeill SA.
PMID: 15661414
Eur Urol. 2005 Feb;47(2):196-201. doi: 10.1016/j.eururo.2004.07.029.

OBJECTIVE: The prostate specific antigen (PSA) era has been associated with a grade migration towards moderately-differentiated (Gleason 5-7) prostate cancer. We investigated whether changes in interpretation of the Gleason system could be a contributing factor by reviewing the Gleason...

Bayesian belief network for the Gleason patterns in prostatic adenocarcinoma: development of a diagnostic decision support system for educational purposes.

Montironi R, Ball RY, Griffiths DF, Grigor K, Harnden PM, Jarmulowicz M, McWilliam LJ, Moseley RP, Parkinson MC, Santinelli A, Moss SM, Melia JW.
PMID: 18459582
Anal Quant Cytol Histol. 2008 Feb;30(1):8-15.

OBJECTIVE: To develop a Bayesian belief network (BBN) for Gleason grading of prostate adenocarcinoma.STUDY DESIGN: A shallow network was developed for Gleason grading with open-tree topology, with a root node containing 5 subjective diagnostic alternatives and 8 first-level descendant...

An assessment of the effects of hormones on short term organ cultures of human breast carcinomata.

Beeby DI, Easty GC, Gazet JC, Grigor K, Neville AM.
PMID: 1156517
Br J Cancer. 1975 Mar;31(3):317-28. doi: 10.1038/bjc.1975.66.
Free PMC Article

Twenty-eight mammary carcinomata were maintained in organ culture in the presence of various hormones. The effects of the hormones have been assessed histologically by estimation of total dehydrogenases activity of the pentose glycolytic pathway and by the incorporation of...

Showing 1 to 12 of 19 entries