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Showing 1 to 8 of 8 entries
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Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.

Bioinformatics and biology insights

Isokpehi RD, Cohly HH, Anyanwu MN, Rajnarayanan RV, Tchounwou PB, Udensi UK, Graham-Evans BE.
PMID: 20981267
Bioinform Biol Insights. 2010 Oct 11;4:99-111. doi: 10.4137/BBI.S5498.

Arsenic is a toxic metalloid that causes skin cancer and binds to cysteine residues-a property that could be used to infer arsenic responsiveness of a target protein. Non-synonymous Single Nucleotide Polymorphisms (nsSNPs) result in amino acid substitutions and may...

Erratum for "Aberrantly Expressed Genes in HaCaT Keratinocytes Chronically Exposed to Arsenic Trioxide".

Biomarker insights

Udensi UK, Cohly HH, Graham-Evans BE, Ndebele K, Garcia-Reyero N, Nanduri B, Tchounwou PB, Isokpehi RD.
PMID: 22084567
Biomark Insights. 2011;6:95. doi: 10.4137/BMI.S8232. Epub 2011 Sep 08.

[This corrects the article on p. 7 in vol. 6, PMID: 21461292.].

Whirlpool sign on ultrasound imaging in a preterm infant with suspected malrotation volvulus.

Archives of disease in childhood. Fetal and neonatal edition

Watts H, Harrison R, Graham-Evans K.
PMID: 33293277
Arch Dis Child Fetal Neonatal Ed. 2021 Jul;106(4):441. doi: 10.1136/archdischild-2020-320804. Epub 2020 Dec 08.

No abstract available.

Ectopic vortex veins and varices in Donnai Barrow syndrome.

Ophthalmic genetics

Higham A, Hildebrand GD, Graham-Evans KAJ, Gilbert RD, Horton R, Hunt D, Shears D, Patel CK.
PMID: 34704885
Ophthalmic Genet. 2021 Oct 27;1-5. doi: 10.1080/13816810.2021.1992787. Epub 2021 Oct 27.

BACKGROUND: Donnai Barrow Syndrome (DBS) is a rare, multi-system autosomal recessively inherited disorder of relevance to ophthalmologists. To aim to describe the ocular phenotype using multimodal imaging for two cases of genetically confirmed DBS and compare against the published...

Aberrantly Expressed Genes in HaCaT Keratinocytes Chronically Exposed to Arsenic Trioxide.

Biomarker insights

Udensi UK, Cohly HH, Graham-Evans BE, Ndebele K, Garcia-Reyero N, Nanduri B, Tchounwou PB, Isokpehi RD.
PMID: 21461292
Biomark Insights. 2011 Feb 08;6:7-16. doi: 10.4137/BMI.S6383.

Inorganic arsenic is a known environmental toxicant and carcinogen of global public health concern. Arsenic is genotoxic and cytotoxic to human keratinocytes. However, the biological pathways perturbed in keratinocytes by low chronic dose inorganic arsenic are not completely understood....

Whirlpool sign on ultrasound imaging in a preterm infant with suspected malrotation volvulus.

Archives of disease in childhood. Fetal and neonatal edition

Watts H, Harrison R, Graham-Evans K.
PMID: 33293277
Arch Dis Child Fetal Neonatal Ed. 2021 Jul;106(4):441. doi: 10.1136/archdischild-2020-320804. Epub 2020 Dec 08.

No abstract available.

Cytotoxicity patterns of arsenic trioxide exposure on HaCaT keratinocytes.

Clinical, cosmetic and investigational dermatology

Udensi UK, Graham-Evans BE, Rogers C, Isokpehi RD.
PMID: 22253543
Clin Cosmet Investig Dermatol. 2011;4:183-90. doi: 10.2147/CCID.S24677. Epub 2011 Dec 09.

BACKGROUND: Arsenic is a ubiquitous environmental toxicant, and abnormalities of the skin are the most common outcomes of long-term, low-dose, chronic arsenic exposure. If the balance between keratinocyte proliferation, differentiation, and death is perturbed, pathologic changes of the epidermis...

Cytotoxic Effect of Arsenic Trioxide in Adenocarcinoma Colorectal Cancer (HT-29) Cells.

Metal ions in biology and medicine : proceedings of the ... International Symposium on Metal Ions in Biology and Medicine held ... = Les ions metalliques en biologie et en medecine : ... Symposium international sur les ions metalliques ...

Stevens JJ, Graham-Evans B, Walker AM, Armstead B, Tchounwou PB.
PMID: 21603592
Met Ions Biol Med. 2008 Jan 01;10:458-462.

Arsenic is a heavy metal that exhibits a high degree of toxicity to various organ systems. In humans, this compound is associated with an increase risk of skin cancer, and may cause cancers of the lung, liver, bladder, kidney,...

Showing 1 to 8 of 8 entries