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Showing 1 to 12 of 351 entries
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Sudden cardiac death in a patient with advanced hepatocellular carcinoma with good response to sorafenib treatment: A case report with literature analysis.

Molecular and clinical oncology

Calistri L, Cordopatri C, Nardi C, Gianni E, Marra F, Colagrande S.
PMID: 28451419
Mol Clin Oncol. 2017 Mar;6(3):389-396. doi: 10.3892/mco.2017.1132. Epub 2017 Jan 16.

Hepatocellular carcinoma (HCC) is the principal primary liver tumor, representing the third largest cause of cancer-associated death worldwide. The actual reference standard systemic treatment for advanced HCC is represented by sorafenib, a multi-targeted orally active small-molecule tyrosine kinase inhibitor....

The effects of propofol cardioplegia on blood and myocardial biomarkers of stress and injury in patients with isolated coronary artery bypass grafting or aortic valve replacement using cardiopulmonary bypass: protocol for a single-center randomized controlled trial.

JMIR research protocols

Plummer ZE, Baos S, Rogers CA, Suleiman MS, Bryan AJ, Angelini GD, Hillier J, Downes R, Nicholson E, Reeves BC.
PMID: 25004932
JMIR Res Protoc. 2014 Jul 08;3(3):e35. doi: 10.2196/resprot.3353.

BACKGROUND: Despite improved myocardial protection strategies, cardioplegic arrest and ischemia still result in reperfusion injury. We have previously published a study describing the effects of propofol (an anesthetic agent commonly used in cardiac surgery) on metabolic stress, cardiac function,...

A time-series study of percutaneous closure of patent foramen ovale: premature adoption?.

Open heart

Lew KN, Angelini GD, Hollingworth W.
PMID: 26835140
Open Heart. 2016 Jan 04;3(1):e000313. doi: 10.1136/openhrt-2015-000313. eCollection 2016.

OBJECTIVES: To evaluate the impact of National Institute for Health and Care Excellence (NICE) guidance in January 2005 and subsequent trial evidence on the adoption of percutaneous closure of patent foramen ovale (PCPFO).METHODS: A retrospective time series study was...

Square Planar (SP-4) and Octahedral (OC-6) Complexes of Platinum(II) and -(IV) with Predetermined Chirality at the Metal Center.

Inorganic chemistry

Gianini M, Forster A, Haag P, von Zelewsky A, Stoeckli-Evans H.
PMID: 11666689
Inorg Chem. 1996 Aug 14;35(17):4889-4895. doi: 10.1021/ic960313o.

cis-Bis-homoleptic platinum(II) complexes, with predetermined helical chirality at the metal center, can be obtained by using strongly sterically interacting ligands. With this aim, two new ligands, (8R,10R)-2-(2'-thienyl)-4,5-pinenopyridine, th4,5ppy (2), and (8R,10R)-2-(2'-thienyl)-5,6-pinenopyridine, th5,6ppy (4), were synthesized and coordinated to platinum....

Search for CP violation in the decays D+--> K(S)pi+ and D+-->K(S)K+.

Physical review letters

Link JM, Reyes M, Yager PM, Anjos JC, Bediaga I, Göbel C, Magnin J, Massafferri A, de Miranda JM, Pepe IM, dos Reis AC, Carrillo S, Casimiro E, Sánchez-Hernández A, Uribe C, Vázquez F, Cinquini L, Cumalat JP, O'Reilly B, Ramirez JE, Vaandering EW, Butler JN, Cheung HW, Gaines I, Garbincius PH, Garren LA, Gottschalk E, Kasper PH, Kreymer AE, Kutschke R, Bianco S, Fabbri FL, Zallo A, Cawlfield C, Kim DY, Rahimi A, Wiss J, Gardner R, Kryemadhi A, Chung YS, Kang JS, Ko BR, Kwak JW, Lee KB, Park H, Alimonti G, Boschini M, D'Angelo P, DiCorato M, Dini P, Giammarchi M, Inzani P, Leveraro F, Malvezzi S, Menasce D, Mezzadri M, Milazzo L, Moroni L, Pedrini D, Pontoglio C, Prelz F, Rovere M, Sala S, Davenport TF, Agostino L, Arena V, Boca G, Bonomi G, Gianini G, Liguori G, Merlo MM, Pantea D, Ratti SP, Riccardi C, Segoni I, Vitulo P, Hernandez H, Lopez AM, Mendez H, Mendez L, Mirles A, Montiel E, Olaya D, Paris A, Quinones J, Rivera C, Xiong W, Zhang Y, Wilson JR, Cho K, Handler T, Mitchell R, Engh D, Hosack M, Johns WE, Nehring M, Sheldon PD, Stenson K, Webster M, Sheaff M.
PMID: 11801103
Phys Rev Lett. 2002 Jan 28;88(4):041602. doi: 10.1103/PhysRevLett.88.041602. Epub 2002 Jan 14.

A high-statistics sample of photoproduced charm from the FOCUS experiment has been used to search for direct CP violation in the decay rates for D+-->K(S)pi+ and D+-->K(S)K+. We have measured the following asymmetry parameters relative to D+-->K-pi+pi+: A(CP)(K(S)pi+) =...

Chiral Cyclometalated Platinum(II) and Palladium(II) Complexes with Derivatives of Thienylpyridine as Ligands: Helical Distortion of the Square Planar (SP-4) Geometry.

Inorganic chemistry

Gianini M, von Zelewsky A, Stoeckli-Evans H.
PMID: 11670245
Inorg Chem. 1997 Dec 17;36(26):6094-6098. doi: 10.1021/ic970228w.

Four cis-bis-cyclometalated complexes of platinum(II) and palladium(II) have been synthesized with chiral substituted thienylpyridine ligands. These ligands are (5aR,6aS)-5,5a,6a,7-tetrahydro-6,6-dimethyl-3-(2'-thienyl)cyclopropa[g]isoquinoline (th4,5capy) (1), (6aR,7aS)-5,6,6a,7a-tetrahydro-7,7-dimethyl-2-(2'-thienyl)cyclopropa[h]quinoline (th5,6capy) (2), (6R,8R)-5,6,7,8-tetrahydro-9,9-dimethyl-2-(2'-thienyl)-6,8-methanoquinoline (th5,6betappy) (3), and (6R,8R)-5,6,7,8-tetrahydro-9,9-dimethyl-3-(2'-thienyl)-6,8-methanoisoquinoline (th4,5ppy) (5). Two complexes have a well-defined chirality at the...

Aggregation of cesium perfluorooctanoate on poly(ethylene glycol) oligomers in water.

The journal of physical chemistry. B

Gianni P, Barghini A, Bernazzani L, Mollica V, Pizzolla P.
PMID: 16671723
J Phys Chem B. 2006 May 11;110(18):9112-21. doi: 10.1021/jp0606614.

The interaction of cesium perfluorooctanoate (CsPFO) with poly(ethylene glycol) (PEG) of different molecular weight (300 < or = MW < or = 20000 Da) has been investigated at 298.15 K by isothermal titration calorimetry (ITC), density, viscosity, and conductivity...

In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.

International journal of high throughput screening

Wilder PT, Charpentier TH, Liriano MA, Gianni K, Varney KM, Pozharski E, Coop A, Toth EA, Mackerell AD, Weber DJ.
PMID: 21132089
Int J High Throughput Screen. 2010 Jul 07;2010(1):109-126. doi: 10.2147/IJHTS.S8210.

S100B is highly over-expressed in many cancers, including malignant melanoma. In such cancers, S100B binds wild-type p53 in a calcium-dependent manner, sequestering it, and promoting its degradation, resulting in the loss of p53-dependent tumor suppression activities. Therefore, S100B inhibitors...

[Importance of some functional and pharmacodynamic stimuli on evaluation of the changes in the repolarization wave of the electrocardiogram noticeable during infectious disease].

La Riforma medica

TUVERI A, GORETTI P, GIANNI L.
PMID: 13592021
Riforma Med. 1958 Sep 27;72(39):1085-95.

No abstract available.

Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis.

Experimental and therapeutic medicine

Stiles J, Amaya C, Pham R, Rowntree RK, Lacaze M, Mulne A, Bischoff J, Kokta V, Boucheron LE, Mitchell DC, Bryan BA.
PMID: 23170111
Exp Ther Med. 2012 Oct;4(4):594-604. doi: 10.3892/etm.2012.654. Epub 2012 Aug 03.

Infantile hemangiomas (IHs) are non-malignant, largely cutaneous vascular tumors affecting approximately 5-10% of children to varying degrees. During the first year of life, these tumors are strongly proliferative, reaching an average size ranging from 2 to 20 cm. These...

Age at onset versus family history and clinical outcomes in 1,665 international bipolar-I disorder patients.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Baldessarini RJ, Tondo L, Vazquez GH, Undurraga J, Bolzani L, Yildiz A, Khalsa HM, Lai M, Lepri B, Lolich M, Maffei PM, Salvatore P, Faedda GL, Vieta E, Tohen M.
PMID: 22295008
World Psychiatry. 2012 Feb;11(1):40-6. doi: 10.1016/j.wpsyc.2012.01.006.

Early onset in bipolar disorder (BPD) has been associated with greater familial risk and unfavorable clinical outcomes. We pooled data from seven international centers to analyze the relationships of family history and symptomatic as well as functional measures of...

Carrier screening for inherited haemoglobin disorders among secondary school students and young adults in Latium, Italy.

Journal of community genetics

Amato A, Cappabianca MP, Lerone M, Colosimo A, Grisanti P, Ponzini D, Di Biagio P, Perri M, Gianni D, Rinaldi S, Piscitelli R.
PMID: 24163007
J Community Genet. 2014 Jul;5(3):265-8. doi: 10.1007/s12687-013-0171-z. Epub 2013 Oct 27.

To reduce the incidence of β-thalassaemia major and other severe haemoglobin-related disorders by the early identification of healthy carriers, the Centro Studi Microcitemie Roma has been organising since 1975 a prevention programme in Latium, an Italian central region. This...

Showing 1 to 12 of 351 entries