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Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate.

Journal of materials science. Materials in medicine

Prádný M, Petrovický P, Fronková V, Vacík J, Smetana K.
PMID: 15348214
J Mater Sci Mater Med. 2002 Jan;13(1):107-11. doi: 10.1023/a:1013659208319.

This study compares subcutaneous and intracerebral biocompatibilty of two hydrogels: copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate and poly(2-hydroxyethyl methacrylate) as reference polymer. The experimental copolymer was more biologically inert than poly(2-hydroxyethyl methacrylate) in both the studied parameters, hence...

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Prádný M, Petrovický P, Fronková V, et al. Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate. J Mater Sci Mater Med. 2002;13(1):107-11doi: 10.1023/a:1013659208319.
Prádný, M., Petrovický, P., Fronková, V., Vacík, J., & Smetana, K. (2002). Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate. Journal of materials science. Materials in medicine, 13(1), 107-11. https://doi.org/10.1023/a:1013659208319
Prádný, Martin, et al. "Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate." Journal of materials science. Materials in medicine vol. 13,1 (2002): 107-11. doi: https://doi.org/10.1023/a:1013659208319
Prádný M, Petrovický P, Fronková V, Vacík J, Smetana K. Evaluation of biocompatibility of the copolymer of 2-hydroxyethyl methacrylate with 2-(methylsulfanyl)ethyl methacrylate. J Mater Sci Mater Med. 2002 Jan;13(1):107-11. doi: 10.1023/a:1013659208319. PMID: 15348214.
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The Use of Rivaroxaban for Unprovoked Pulmonary Embolism in the Setting of Antithrombin Deficiency.

Cureus

Gryn OJ, Nguyen T, Frankova D.
PMID: 32670697
Cureus. 2020 Jun 11;12(6):e8560. doi: 10.7759/cureus.8560.

A 24-year-old woman with antithrombin (AT) deficiency presented with right-sided pleuritic chest pain of five days duration with diagnosis of pulmonary embolism (PE) made at an outside hospital. After discussion of treatment options with the patient, her treatment was...

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Gryn OJ, Nguyen T, Frankova D. The Use of Rivaroxaban for Unprovoked Pulmonary Embolism in the Setting of Antithrombin Deficiency. Cureus. 2020;12(6):e8560doi: 10.7759/cureus.8560.
Gryn, O. J., Nguyen, T., & Frankova, D. (2020). The Use of Rivaroxaban for Unprovoked Pulmonary Embolism in the Setting of Antithrombin Deficiency. Cureus, 12(6), e8560. https://doi.org/10.7759/cureus.8560
Gryn, Oscar J, et al. "The Use of Rivaroxaban for Unprovoked Pulmonary Embolism in the Setting of Antithrombin Deficiency." Cureus vol. 12,6 (2020): e8560. doi: https://doi.org/10.7759/cureus.8560
Gryn OJ, Nguyen T, Frankova D. The Use of Rivaroxaban for Unprovoked Pulmonary Embolism in the Setting of Antithrombin Deficiency. Cureus. 2020 Jun 11;12(6):e8560. doi: 10.7759/cureus.8560. PMID: 32670697; PMCID: PMC7358900.
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Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes.

Cancer treatment and research communications

Franko J, Le VH, Tee MC, Lin M, Sedinkin J, Raman S, Frankova D.
PMID: 34655861
Cancer Treat Res Commun. 2021;29:100475. doi: 10.1016/j.ctarc.2021.100475. Epub 2021 Oct 11.

BACKGROUND: Signet ring cell carcinoma (SRCC) is a distinct malignancy occurring across the tubular gastrointestinal tract (tGIT). We comprehensively examined the outcomes of patients diagnosed with SRCC across tGIT.METHODS: SRCC and not-otherwise-specified adenocarcinoma (NOS) patients reported to the National...

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Franko J, Le VH, Tee MC, et al. Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes. Cancer Treat Res Commun. 2021;29:100475doi: 10.1016/j.ctarc.2021.100475.
Franko, J., Le, V. H., Tee, M. C., Lin, M., Sedinkin, J., Raman, S., & Frankova, D. (2021). Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes. Cancer treatment and research communications, 29100475. https://doi.org/10.1016/j.ctarc.2021.100475
Franko, Jan, et al. "Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes." Cancer treatment and research communications vol. 29 (2021): 100475. doi: https://doi.org/10.1016/j.ctarc.2021.100475
Franko J, Le VH, Tee MC, Lin M, Sedinkin J, Raman S, Frankova D. Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes. Cancer Treat Res Commun. 2021;29:100475. doi: 10.1016/j.ctarc.2021.100475. Epub 2021 Oct 11. PMID: 34655861.
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Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes.

Cancer treatment and research communications

Franko J, Le VH, Tee MC, Lin M, Sedinkin J, Raman S, Frankova D.
PMID: 34655861
Cancer Treat Res Commun. 2021 Oct 11;29:100475. doi: 10.1016/j.ctarc.2021.100475. Epub 2021 Oct 11.

BACKGROUND: Signet ring cell carcinoma (SRCC) is a distinct malignancy occurring across the tubular gastrointestinal tract (tGIT). We comprehensively examined the outcomes of patients diagnosed with SRCC across tGIT.METHODS: SRCC and not-otherwise-specified adenocarcinoma (NOS) patients reported to the National...

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Franko J, Le VH, Tee MC, et al. Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes. Cancer Treat Res Commun. 2021;29:100475doi: 10.1016/j.ctarc.2021.100475.
Franko, J., Le, V. H., Tee, M. C., Lin, M., Sedinkin, J., Raman, S., & Frankova, D. (2021). Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes. Cancer treatment and research communications, 29100475. https://doi.org/10.1016/j.ctarc.2021.100475
Franko, Jan, et al. "Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes." Cancer treatment and research communications vol. 29 (2021): 100475. doi: https://doi.org/10.1016/j.ctarc.2021.100475
Franko J, Le VH, Tee MC, Lin M, Sedinkin J, Raman S, Frankova D. Signet ring cell carcinoma of the gastrointestinal tract: National trends on treatment effects and prognostic outcomes. Cancer Treat Res Commun. 2021 Oct 11;29:100475. doi: 10.1016/j.ctarc.2021.100475. Epub 2021 Oct 11. PMID: 34655861.
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Factors Influencing Parental Awareness about Newborn Screening.

International journal of neonatal screening

Franková V, Dohnalová A, Pešková K, Hermánková R, O'Driscoll R, Ješina P, Kožich V.
PMID: 33072994
Int J Neonatal Screen. 2019 Sep 18;5(3):35. doi: 10.3390/ijns5030035. eCollection 2019 Sep.

Appropriate and timely education about newborn screening (NBS) helps to foster benefits such as prompt follow up, to promote parents' autonomy via informed consent and minimize the harms such as reducing the impact of NBS false-positive results. The aim...

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Franková V, Dohnalová A, Pešková K, et al. Factors Influencing Parental Awareness about Newborn Screening. Int J Neonatal Screen. 2019;5(3):35doi: 10.3390/ijns5030035.
Franková, V., Dohnalová, A., Pešková, K., Hermánková, R., O'Driscoll, R., Ješina, P., & Kožich, V. (2019). Factors Influencing Parental Awareness about Newborn Screening. International journal of neonatal screening, 5(3), 35. https://doi.org/10.3390/ijns5030035
Franková, Věra, et al. "Factors Influencing Parental Awareness about Newborn Screening." International journal of neonatal screening vol. 5,3 (2019): 35. doi: https://doi.org/10.3390/ijns5030035
Franková V, Dohnalová A, Pešková K, Hermánková R, O'Driscoll R, Ješina P, Kožich V. Factors Influencing Parental Awareness about Newborn Screening. Int J Neonatal Screen. 2019 Sep 18;5(3):35. doi: 10.3390/ijns5030035. eCollection 2019 Sep. PMID: 33072994; PMCID: PMC7510194.
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Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro.

Journal of applied biomedicine

Sklenarova R, Svrckova M, Hodek P, Ulrichova J, Frankova J.
PMID: 34907758
J Appl Biomed. 2021 Sep;19(3):149-158. doi: 10.32725/jab.2021.017. Epub 2021 Aug 10.

Myricetin (MYR) and dihydromyricetin (DHM) are classified as natural flavonoids. Both substances are known for their anti-inflammatory and antioxidant properties. In this study, an in vitro model of inflammation was demonstrated on monolayers of scratched fibroblasts or keratinocytes exposed...

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Sklenarova R, Svrckova M, Hodek P, et al. Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro. J Appl Biomed. 2021;19(3):149-158doi: 10.32725/jab.2021.017.
Sklenarova, R., Svrckova, M., Hodek, P., Ulrichova, J., & Frankova, J. (2021). Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro. Journal of applied biomedicine, 19(3), 149-158. https://doi.org/10.32725/jab.2021.017
Sklenarova, Renata, et al. "Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro." Journal of applied biomedicine vol. 19,3 (2021): 149-158. doi: https://doi.org/10.32725/jab.2021.017
Sklenarova R, Svrckova M, Hodek P, Ulrichova J, Frankova J. Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro. J Appl Biomed. 2021 Sep;19(3):149-158. doi: 10.32725/jab.2021.017. Epub 2021 Aug 10. PMID: 34907758.
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Portal hypertension is the main driver of liver stiffness in advanced liver cirrhosis.

Physiological research

Lunova M, Frankova S, Gottfriedova H, Senkerikova R, Neroldova M, Kovac J, Kieslichova E, Lanska V, Sticova E, Spicak J, Jirsa M, Sperl J.
PMID: 34062072
Physiol Res. 2021 Aug 31;70(4):563-577. doi: 10.33549/physiolres.934626. Epub 2021 Jun 01.

Liver stiffness (LS) is a novel non-invasive parameter widely used in clinical hepatology. LS correlates with liver fibrosis stage in non-cirrhotic patients. In cirrhotic patients it also shows good correlation with Hepatic Venous Pressure Gradient (HVPG). Our aim was...

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Lunova M, Frankova S, Gottfriedova H, et al. Portal hypertension is the main driver of liver stiffness in advanced liver cirrhosis. Physiol Res. 2021;70(4):563-577doi: 10.33549/physiolres.934626.
Lunova, M., Frankova, S., Gottfriedova, H., Senkerikova, R., Neroldova, M., Kovac, J., Kieslichova, E., Lanska, V., Sticova, E., Spicak, J., Jirsa, M., & Sperl, J. (2021). Portal hypertension is the main driver of liver stiffness in advanced liver cirrhosis. Physiological research, 70(4), 563-577. https://doi.org/10.33549/physiolres.934626
Lunova, M, et al. "Portal hypertension is the main driver of liver stiffness in advanced liver cirrhosis." Physiological research vol. 70,4 (2021): 563-577. doi: https://doi.org/10.33549/physiolres.934626
Lunova M, Frankova S, Gottfriedova H, Senkerikova R, Neroldova M, Kovac J, Kieslichova E, Lanska V, Sticova E, Spicak J, Jirsa M, Sperl J. Portal hypertension is the main driver of liver stiffness in advanced liver cirrhosis. Physiol Res. 2021 Aug 31;70(4):563-577. doi: 10.33549/physiolres.934626. Epub 2021 Jun 01. PMID: 34062072.
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Fecal zonulin is elevated in Crohn's disease and in cigarette smokers.

Practical laboratory medicine

Malíčková K, Francová I, Lukáš M, Kolář M, Králíková E, Bortlík M, Ďuricová D, Štěpánková L, Zvolská K, Pánková A, Zima T.
PMID: 29034305
Pract Lab Med. 2017 Sep 23;9:39-44. doi: 10.1016/j.plabm.2017.09.001. eCollection 2017 Dec.

OBJECTIVES: Human zonulin is a protein that increases permeability in the epithelial layer of the small intestine by reversibly modulating the intercellular tight junctions. There is not sufficient information available about zonulin's participation in inflammatory bowel diseases (IBD). The...

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Malíčková K, Francová I, Lukáš M, et al. Fecal zonulin is elevated in Crohn's disease and in cigarette smokers. Pract Lab Med. 2017;9:39-44doi: 10.1016/j.plabm.2017.09.001.
Malíčková, K., Francová, I., Lukáš, M., Kolář, M., Králíková, E., Bortlík, M., Ďuricová, D., Štěpánková, L., Zvolská, K., Pánková, A., & Zima, T. (2017). Fecal zonulin is elevated in Crohn's disease and in cigarette smokers. Practical laboratory medicine, 939-44. https://doi.org/10.1016/j.plabm.2017.09.001
Malíčková, Karin, et al. "Fecal zonulin is elevated in Crohn's disease and in cigarette smokers." Practical laboratory medicine vol. 9 (2017): 39-44. doi: https://doi.org/10.1016/j.plabm.2017.09.001
Malíčková K, Francová I, Lukáš M, Kolář M, Králíková E, Bortlík M, Ďuricová D, Štěpánková L, Zvolská K, Pánková A, Zima T. Fecal zonulin is elevated in Crohn's disease and in cigarette smokers. Pract Lab Med. 2017 Sep 23;9:39-44. doi: 10.1016/j.plabm.2017.09.001. eCollection 2017 Dec. PMID: 29034305; PMCID: PMC5633835.
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Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus.

Parasites & vectors

Franta Z, Frantová H, Konvičková J, Horn M, Sojka D, Mareš M, Kopáček P.
PMID: 21156061
Parasit Vectors. 2010 Dec 14;3:119. doi: 10.1186/1756-3305-3-119.

BACKGROUND: Ticks are vectors of a wide variety of pathogens causing severe diseases in humans and domestic animals. Intestinal digestion of the host blood is an essential process of tick physiology and also a limiting factor for pathogen transmission...

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Franta Z, Frantová H, Konvičková J, et al. Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. Parasit Vectors. 2010;3:119doi: 10.1186/1756-3305-3-119.
Franta, Z., Frantová, H., Konvičková, J., Horn, M., Sojka, D., Mareš, M., & Kopáček, P. (2010). Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. Parasites & vectors, 3119. https://doi.org/10.1186/1756-3305-3-119
Franta, Zdeněk, et al. "Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus." Parasites & vectors vol. 3 (2010): 119. doi: https://doi.org/10.1186/1756-3305-3-119
Franta Z, Frantová H, Konvičková J, Horn M, Sojka D, Mareš M, Kopáček P. Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. Parasit Vectors. 2010 Dec 14;3:119. doi: 10.1186/1756-3305-3-119. PMID: 21156061; PMCID: PMC3016361.
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High-pressure synthesis and characterization of Li2Ca3[N2]3--an uncommon metallic diazenide with [N2]2- ions.

Journal of the American Chemical Society

Schneider SB, Seibald M, Deringer VL, Stoffel RP, Frankovsky R, Friederichs GM, Laqua H, Duppel V, Jeschke G, Dronskowski R, Schnick W.
PMID: 24090235
J Am Chem Soc. 2013 Nov 06;135(44):16668-79. doi: 10.1021/ja408816t.

Dinitrogen (N2) ligation is a common and well-characterized structural motif in bioinorganic synthesis. In solid-state chemistry, on the other hand, homonuclear dinitrogen entities as structural building units proved existence only very recently. High-pressure/high-temperature (HP/HT) syntheses have afforded a number...

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Schneider SB, Seibald M, Deringer VL, et al. High-pressure synthesis and characterization of Li2Ca3[N2]3--an uncommon metallic diazenide with [N2]2- ions. J Am Chem Soc. 2013;135(44):16668-79doi: 10.1021/ja408816t.
Schneider, S. B., Seibald, M., Deringer, V. L., Stoffel, R. P., Frankovsky, R., Friederichs, G. M., Laqua, H., Duppel, V., Jeschke, G., Dronskowski, R., & Schnick, W. (2013). High-pressure synthesis and characterization of Li2Ca3[N2]3--an uncommon metallic diazenide with [N2]2- ions. Journal of the American Chemical Society, 135(44), 16668-79. https://doi.org/10.1021/ja408816t
Schneider, Sebastian B, et al. "High-pressure synthesis and characterization of Li2Ca3[N2]3--an uncommon metallic diazenide with [N2]2- ions." Journal of the American Chemical Society vol. 135,44 (2013): 16668-79. doi: https://doi.org/10.1021/ja408816t
Schneider SB, Seibald M, Deringer VL, Stoffel RP, Frankovsky R, Friederichs GM, Laqua H, Duppel V, Jeschke G, Dronskowski R, Schnick W. High-pressure synthesis and characterization of Li2Ca3[N2]3--an uncommon metallic diazenide with [N2]2- ions. J Am Chem Soc. 2013 Nov 06;135(44):16668-79. doi: 10.1021/ja408816t. PMID: 24090235.
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USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study.

Therapeutics and clinical risk management

Frankova S, Jirsa M, Merta D, Neroldova M, Urbanek P, Senkerikova R, Spicak J, Sperl J.
PMID: 26719699
Ther Clin Risk Manag. 2015 Dec 17;11:1853-61. doi: 10.2147/TCRM.S94010. eCollection 2015.

BACKGROUND AND AIMS: Patients with advanced liver fibrosis owing to chronic hepatitis C virus genotype 1 represent a difficult-to-treat group even if a protease inhibitor is added to pegylated interferon alpha and ribavirin. Therefore, only patients with a high...

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Frankova S, Jirsa M, Merta D, et al. USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study. Ther Clin Risk Manag. 2015;11:1853-61doi: 10.2147/TCRM.S94010.
Frankova, S., Jirsa, M., Merta, D., Neroldova, M., Urbanek, P., Senkerikova, R., Spicak, J., & Sperl, J. (2015). USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study. Therapeutics and clinical risk management, 111853-61. https://doi.org/10.2147/TCRM.S94010
Frankova, Sona, et al. "USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study." Therapeutics and clinical risk management vol. 11 (2015): 1853-61. doi: https://doi.org/10.2147/TCRM.S94010
Frankova S, Jirsa M, Merta D, Neroldova M, Urbanek P, Senkerikova R, Spicak J, Sperl J. USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study. Ther Clin Risk Manag. 2015 Dec 17;11:1853-61. doi: 10.2147/TCRM.S94010. eCollection 2015. PMID: 26719699; PMCID: PMC4687952.
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Secreted Enzyme-Responsive System for Controlled Antifungal Agent Release.

Nanomaterials (Basel, Switzerland)

Bernardos A, Božik M, Montero A, Pérez-Esteve É, García-Casado E, Lhotka M, Fraňková A, Marcos MD, Barat JM, Martínez-Máñez R, Klouček P.
PMID: 34068155
Nanomaterials (Basel). 2021 May 13;11(5). doi: 10.3390/nano11051280.

Essential oil components (EOCs) such as eugenol play a significant role in plant antimicrobial defense. Due to the volatility and general reactivity of these molecules, plants have evolved smart systems for their storage and release, which are key prerequisites...

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Bernardos A, Božik M, Montero A, et al. Secreted Enzyme-Responsive System for Controlled Antifungal Agent Release. Nanomaterials (Basel). 2021;11(5)doi: 10.3390/nano11051280.
Bernardos, A., Božik, M., Montero, A., Pérez-Esteve, �. �., García-Casado, E., Lhotka, M., Fraňková, A., Marcos, M. D., Barat, J. M., Martínez-Máñez, R., & Klouček, P. (2021). Secreted Enzyme-Responsive System for Controlled Antifungal Agent Release. Nanomaterials (Basel, Switzerland), 11(5), . https://doi.org/10.3390/nano11051280
Bernardos, Andrea, et al. "Secreted Enzyme-Responsive System for Controlled Antifungal Agent Release." Nanomaterials (Basel, Switzerland) vol. 11,5 (2021). doi: https://doi.org/10.3390/nano11051280
Bernardos A, Božik M, Montero A, Pérez-Esteve É, García-Casado E, Lhotka M, Fraňková A, Marcos MD, Barat JM, Martínez-Máñez R, Klouček P. Secreted Enzyme-Responsive System for Controlled Antifungal Agent Release. Nanomaterials (Basel). 2021 May 13;11(5). doi: 10.3390/nano11051280. PMID: 34068155; PMCID: PMC8153022.
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