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Synthesis, Physicochemical Studies, Molecular Dynamics Simulations, and Metal-Ion-Dependent Antiproliferative and Antiangiogenic Properties of Cone ICL670-Substituted Calix[4]arenes.

ChemPlusChem

Rouge P, Dassonville-Klimpt A, Cézard C, Boudesocque S, Ourouda R, Amant C, Gaboriau F, Forfar I, Guillon J, Guillon E, Vanquelef E, Cieplak P, Dupradeau FY, Dupont L, Sonnet P.
PMID: 25599014
Chempluschem. 2012 Nov 01;77(11):1001-1016. doi: 10.1002/cplu.201200141.

Iron chelators, through their capacity to modulate the iron concentration in cells, are promising molecules for cancer chemotherapy. Chelators with high lipophilicity easily enter into cells and deplete the iron intracellular pool. Consequently, iron-dependent enzymes, such as ribonucleotide reductase,...

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Rouge P, Dassonville-Klimpt A, Cézard C, et al. Synthesis, Physicochemical Studies, Molecular Dynamics Simulations, and Metal-Ion-Dependent Antiproliferative and Antiangiogenic Properties of Cone ICL670-Substituted Calix[4]arenes. Chempluschem. 2012;77(11):1001-1016doi: 10.1002/cplu.201200141.
Rouge, P., Dassonville-Klimpt, A., Cézard, C., Boudesocque, S., Ourouda, R., Amant, C., Gaboriau, F., Forfar, I., Guillon, J., Guillon, E., Vanquelef, E., Cieplak, P., Dupradeau, F. Y., Dupont, L., & Sonnet, P. (2012). Synthesis, Physicochemical Studies, Molecular Dynamics Simulations, and Metal-Ion-Dependent Antiproliferative and Antiangiogenic Properties of Cone ICL670-Substituted Calix[4]arenes. ChemPlusChem, 77(11), 1001-1016. https://doi.org/10.1002/cplu.201200141
Rouge, Pascal, et al. "Synthesis, Physicochemical Studies, Molecular Dynamics Simulations, and Metal-Ion-Dependent Antiproliferative and Antiangiogenic Properties of Cone ICL670-Substituted Calix[4]arenes." ChemPlusChem vol. 77,11 (2012): 1001-1016. doi: https://doi.org/10.1002/cplu.201200141
Rouge P, Dassonville-Klimpt A, Cézard C, Boudesocque S, Ourouda R, Amant C, Gaboriau F, Forfar I, Guillon J, Guillon E, Vanquelef E, Cieplak P, Dupradeau FY, Dupont L, Sonnet P. Synthesis, Physicochemical Studies, Molecular Dynamics Simulations, and Metal-Ion-Dependent Antiproliferative and Antiangiogenic Properties of Cone ICL670-Substituted Calix[4]arenes. Chempluschem. 2012 Nov 01;77(11):1001-1016. doi: 10.1002/cplu.201200141. PMID: 25599014; PMCID: PMC4293705.
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A method of collecting total excreta in infants.

Archives of disease in childhood

FORFAR JO, PRAIN JH.
PMID: 14783434
Arch Dis Child. 1950 Sep;25(123):260-1. doi: 10.1136/adc.25.123.260.

No abstract available.

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FORFAR JO, PRAIN JH. A method of collecting total excreta in infants. Arch Dis Child. 1950;25(123):260-1doi: 10.1136/adc.25.123.260.
FORFAR, J. O., & PRAIN, J. H. (1950). A method of collecting total excreta in infants. Archives of disease in childhood, 25(123), 260-1. https://doi.org/10.1136/adc.25.123.260
FORFAR, J O, and PRAIN, J H. "A method of collecting total excreta in infants." Archives of disease in childhood vol. 25,123 (1950): 260-1. doi: https://doi.org/10.1136/adc.25.123.260
FORFAR JO, PRAIN JH. A method of collecting total excreta in infants. Arch Dis Child. 1950 Sep;25(123):260-1. doi: 10.1136/adc.25.123.260. PMID: 14783434; PMCID: PMC1988306.
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12 articles of 1926.

Archives of disease in childhood

Forfar JO, Mowat AP, Clarke CA, Chiswick ML, Gordon N, McNeish AS, Booth IW, Bower BD, Arneil GC, Walker-Smith JA, Smithells RW, Wigglesworth JS, Robinson RJ.
PMID: 21032750
Arch Dis Child. 1986 Oct;61(10):939-65. doi: 10.1136/adc.61.10.939.

No abstract available.

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Forfar JO, Mowat AP, Clarke CA, et al. 12 articles of 1926. Arch Dis Child. 1986;61(10):939-65doi: 10.1136/adc.61.10.939.
Forfar, J. O., Mowat, A. P., Clarke, C. A., Chiswick, M. L., Gordon, N., McNeish, A. S., Booth, I. W., Bower, B. D., Arneil, G. C., Walker-Smith, J. A., Smithells, R. W., Wigglesworth, J. S., & Robinson, R. J. (1986). 12 articles of 1926. Archives of disease in childhood, 61(10), 939-65. https://doi.org/10.1136/adc.61.10.939
Forfar, J O, et al. "12 articles of 1926." Archives of disease in childhood vol. 61,10 (1986): 939-65. doi: https://doi.org/10.1136/adc.61.10.939
Forfar JO, Mowat AP, Clarke CA, Chiswick ML, Gordon N, McNeish AS, Booth IW, Bower BD, Arneil GC, Walker-Smith JA, Smithells RW, Wigglesworth JS, Robinson RJ. 12 articles of 1926. Arch Dis Child. 1986 Oct;61(10):939-65. doi: 10.1136/adc.61.10.939. PMID: 21032750; PMCID: PMC1777966.
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One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs.

Biochimica et biophysica acta

Lock A, Forfar R, Weston C, Bowsher L, Upton GJ, Reynolds CA, Ladds G, Dixon AM.
PMID: 25157670
Biochim Biophys Acta. 2014 Dec;1838(12):3036-51. doi: 10.1016/j.bbamem.2014.08.019. Epub 2014 Aug 23.

G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors in mammals and facilitate a range of physiological responses triggered by a variety of ligands. GPCRs were thought to function as monomers, however it is now accepted that...

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Lock A, Forfar R, Weston C, et al. One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs. Biochim Biophys Acta. 2014;1838(12):3036-51doi: 10.1016/j.bbamem.2014.08.019.
Lock, A., Forfar, R., Weston, C., Bowsher, L., Upton, G. J., Reynolds, C. A., Ladds, G., & Dixon, A. M. (2014). One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs. Biochimica et biophysica acta, 1838(12), 3036-51. https://doi.org/10.1016/j.bbamem.2014.08.019
Lock, Antonia, et al. "One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs." Biochimica et biophysica acta vol. 1838,12 (2014): 3036-51. doi: https://doi.org/10.1016/j.bbamem.2014.08.019
Lock A, Forfar R, Weston C, Bowsher L, Upton GJ, Reynolds CA, Ladds G, Dixon AM. One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs. Biochim Biophys Acta. 2014 Dec;1838(12):3036-51. doi: 10.1016/j.bbamem.2014.08.019. Epub 2014 Aug 23. PMID: 25157670.
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Adenosine Receptor Activation in the "Trigger" Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s).

JACC. Basic to translational science

Contractor H, Lie RH, Cunnington C, Li J, Støttrup NB, Manlhiot C, Bøtker HE, Schmidt MR, Forfar JC, Ashrafian H, Redington A, Kharbanda RK.
PMID: 30167533
JACC Basic Transl Sci. 2016 Sep 28;1(6):461-471. doi: 10.1016/j.jacbts.2016.06.002. eCollection 2016 Oct.

Remote ischemic pre-conditioning (rIPC) has emerged as a potential mechanism to reduce ischemia-reperfusion injury. Clinical data, however, have been mixed, and its physiological basis remains unclear, although it appears to involve release of circulating factor(s) and/or neural pathways. Here,...

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Contractor H, Lie RH, Cunnington C, et al. Adenosine Receptor Activation in the "Trigger" Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s). JACC Basic Transl Sci. 2016;1(6):461-471doi: 10.1016/j.jacbts.2016.06.002.
Contractor, H., Lie, R. H., Cunnington, C., Li, J., Støttrup, N. B., Manlhiot, C., Bøtker, H. E., Schmidt, M. R., Forfar, J. C., Ashrafian, H., Redington, A., & Kharbanda, R. K. (2016). Adenosine Receptor Activation in the "Trigger" Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s). JACC. Basic to translational science, 1(6), 461-471. https://doi.org/10.1016/j.jacbts.2016.06.002
Contractor, Hussain, et al. "Adenosine Receptor Activation in the "Trigger" Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s)." JACC. Basic to translational science vol. 1,6 (2016): 461-471. doi: https://doi.org/10.1016/j.jacbts.2016.06.002
Contractor H, Lie RH, Cunnington C, Li J, Støttrup NB, Manlhiot C, Bøtker HE, Schmidt MR, Forfar JC, Ashrafian H, Redington A, Kharbanda RK. Adenosine Receptor Activation in the "Trigger" Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s). JACC Basic Transl Sci. 2016 Sep 28;1(6):461-471. doi: 10.1016/j.jacbts.2016.06.002. eCollection 2016 Oct. PMID: 30167533; PMCID: PMC6113421.
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X-ray crystal structure of [.

Acta crystallographica. Section E, Crystallographic communications

Drescher SL, Forfar CP, Boeré RT, Hayes PG.
PMID: 34667631
Acta Crystallogr E Crystallogr Commun. 2021 Sep 17;77:1025-1028. doi: 10.1107/S2056989021009221. eCollection 2021 Oct 01.

The compound bis-{μ

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Drescher SL, Forfar CP, Boeré RT, et al. X-ray crystal structure of [. Acta Crystallogr E Crystallogr Commun. 2021;77:1025-1028doi: 10.1107/S2056989021009221.
Drescher, S. L., Forfar, C. P., Boeré, R. T., & Hayes, P. G. (2021). X-ray crystal structure of [. Acta crystallographica. Section E, Crystallographic communications, 771025-1028. https://doi.org/10.1107/S2056989021009221
Drescher, Sam L, et al. "X-ray crystal structure of [." Acta crystallographica. Section E, Crystallographic communications vol. 77 (2021): 1025-1028. doi: https://doi.org/10.1107/S2056989021009221
Drescher SL, Forfar CP, Boeré RT, Hayes PG. X-ray crystal structure of [. Acta Crystallogr E Crystallogr Commun. 2021 Sep 17;77:1025-1028. doi: 10.1107/S2056989021009221. eCollection 2021 Oct 01. PMID: 34667631; PMCID: PMC8491533.
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Effective thrombus extraction strategies in acute saphenous vein graft intervention.

BMJ case reports

Schrale R, Choudhury RP, Forfar C.
PMID: 21687107
BMJ Case Rep. 2009;2009:bcr2006088310. doi: 10.1136/bcr.2006.088310. Epub 2009 Feb 18.

No abstract available.

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Schrale R, Choudhury RP, Forfar C. Effective thrombus extraction strategies in acute saphenous vein graft intervention. BMJ Case Rep. 2009;2009:bcr2006088310doi: 10.1136/bcr.2006.088310.
Schrale, R., Choudhury, R. P., & Forfar, C. (2009). Effective thrombus extraction strategies in acute saphenous vein graft intervention. BMJ case reports, 2009bcr2006088310. https://doi.org/10.1136/bcr.2006.088310
Schrale, R, et al. "Effective thrombus extraction strategies in acute saphenous vein graft intervention." BMJ case reports vol. 2009 (2009): bcr2006088310. doi: https://doi.org/10.1136/bcr.2006.088310
Schrale R, Choudhury RP, Forfar C. Effective thrombus extraction strategies in acute saphenous vein graft intervention. BMJ Case Rep. 2009;2009:bcr2006088310. doi: 10.1136/bcr.2006.088310. Epub 2009 Feb 18. PMID: 21687107; PMCID: PMC3105934.
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Retraction notice to Gadolinium-Free Cardiac MR Stress T1-Mapping to Distinguish Epicardial From Microvascular Coronary Disease: J Am Coll Cardiol 71 (2018) 957-968.

Journal of the American College of Cardiology

Liu A, Wijesurendra RS, Liu JM, Greiser A, Jerosch-Herold M, Forfar JC, Channon KM, Piechnik SK, Neubauer S, Kharbanda RK, Ferreira VM.
PMID: 33059839
J Am Coll Cardiol. 2020 Oct 20;76(16):1915. doi: 10.1016/j.jacc.2020.08.038.

No abstract available.

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Liu A, Wijesurendra RS, Liu JM, et al. Retraction notice to Gadolinium-Free Cardiac MR Stress T1-Mapping to Distinguish Epicardial From Microvascular Coronary Disease: J Am Coll Cardiol 71 (2018) 957-968. J Am Coll Cardiol. 2020;76(16):1915doi: 10.1016/j.jacc.2020.08.038.
Liu, A., Wijesurendra, R. S., Liu, J. M., Greiser, A., Jerosch-Herold, M., Forfar, J. C., Channon, K. M., Piechnik, S. K., Neubauer, S., Kharbanda, R. K., & Ferreira, V. M. (2020). Retraction notice to Gadolinium-Free Cardiac MR Stress T1-Mapping to Distinguish Epicardial From Microvascular Coronary Disease: J Am Coll Cardiol 71 (2018) 957-968. Journal of the American College of Cardiology, 76(16), 1915. https://doi.org/10.1016/j.jacc.2020.08.038
Liu, Alexander, et al. "Retraction notice to Gadolinium-Free Cardiac MR Stress T1-Mapping to Distinguish Epicardial From Microvascular Coronary Disease: J Am Coll Cardiol 71 (2018) 957-968." Journal of the American College of Cardiology vol. 76,16 (2020): 1915. doi: https://doi.org/10.1016/j.jacc.2020.08.038
Liu A, Wijesurendra RS, Liu JM, Greiser A, Jerosch-Herold M, Forfar JC, Channon KM, Piechnik SK, Neubauer S, Kharbanda RK, Ferreira VM. Retraction notice to Gadolinium-Free Cardiac MR Stress T1-Mapping to Distinguish Epicardial From Microvascular Coronary Disease: J Am Coll Cardiol 71 (2018) 957-968. J Am Coll Cardiol. 2020 Oct 20;76(16):1915. doi: 10.1016/j.jacc.2020.08.038. PMID: 33059839; PMCID: PMC8055537.
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Decrease of Pdzrn3 is required for heart maturation and protects against heart failure.

Scientific reports

Pernot M, Jaspard-Vinassa B, Abelanet A, Rubin S, Forfar I, Jeanningros S, Cetran L, Yu MH, Balse E, Hatem S, Dufourcq P, Couffinhal T, Duplàa C.
PMID: 34996942
Sci Rep. 2022 Jan 07;12(1):8. doi: 10.1038/s41598-021-03795-7.

Heart failure is the final common stage of most cardiopathies. Cardiomyocytes (CM) connect with others via their extremities by intercalated disk protein complexes. This planar and directional organization of myocytes is crucial for mechanical coupling and anisotropic conduction of...

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Pernot M, Jaspard-Vinassa B, Abelanet A, et al. Decrease of Pdzrn3 is required for heart maturation and protects against heart failure. Sci Rep. 2022;12(1):8doi: 10.1038/s41598-021-03795-7.
Pernot, M., Jaspard-Vinassa, B., Abelanet, A., Rubin, S., Forfar, I., Jeanningros, S., Cetran, L., Yu, M. H., Balse, E., Hatem, S., Dufourcq, P., Couffinhal, T., & Duplàa, C. (2022). Decrease of Pdzrn3 is required for heart maturation and protects against heart failure. Scientific reports, 12(1), 8. https://doi.org/10.1038/s41598-021-03795-7
Pernot, Mathieu, et al. "Decrease of Pdzrn3 is required for heart maturation and protects against heart failure." Scientific reports vol. 12,1 (2022): 8. doi: https://doi.org/10.1038/s41598-021-03795-7
Pernot M, Jaspard-Vinassa B, Abelanet A, Rubin S, Forfar I, Jeanningros S, Cetran L, Yu MH, Balse E, Hatem S, Dufourcq P, Couffinhal T, Duplàa C. Decrease of Pdzrn3 is required for heart maturation and protects against heart failure. Sci Rep. 2022 Jan 07;12(1):8. doi: 10.1038/s41598-021-03795-7. PMID: 34996942.
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White phosphorus as a ligand for the coinage metals.

Chemical communications (Cambridge, England)

Forfar LC, Clark TJ, Green M, Mansell SM, Russell CA, Sanguramath RA, Slattery JM.
PMID: 22234580
Chem Commun (Camb). 2012 Feb 14;48(14):1970-2. doi: 10.1039/c2cc15291f. Epub 2012 Jan 11.

Reaction of equimolar quantities of MX (M = Au, Cu, X = Cl; M = Ag, X = OTf) and GaCl(3) in CH(2)Cl(2) with P(4) leads to phosphorus ligating a cationic coinage metal centre. For Cu and Ag, ion-contacted...

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Forfar LC, Clark TJ, Green M, et al. White phosphorus as a ligand for the coinage metals. Chem Commun (Camb). 2012;48(14):1970-2doi: 10.1039/c2cc15291f.
Forfar, L. C., Clark, T. J., Green, M., Mansell, S. M., Russell, C. A., Sanguramath, R. A., & Slattery, J. M. (2012). White phosphorus as a ligand for the coinage metals. Chemical communications (Cambridge, England), 48(14), 1970-2. https://doi.org/10.1039/c2cc15291f
Forfar, Laura C, et al. "White phosphorus as a ligand for the coinage metals." Chemical communications (Cambridge, England) vol. 48,14 (2012): 1970-2. doi: https://doi.org/10.1039/c2cc15291f
Forfar LC, Clark TJ, Green M, Mansell SM, Russell CA, Sanguramath RA, Slattery JM. White phosphorus as a ligand for the coinage metals. Chem Commun (Camb). 2012 Feb 14;48(14):1970-2. doi: 10.1039/c2cc15291f. Epub 2012 Jan 11. PMID: 22234580.
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ACTH Antagonists.

Frontiers in endocrinology

Clark AJ, Forfar R, Hussain M, Jerman J, McIver E, Taylor D, Chan L.
PMID: 27547198
Front Endocrinol (Lausanne). 2016 Aug 05;7:101. doi: 10.3389/fendo.2016.00101. eCollection 2016.

Adrenocorticotropin (ACTH) acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors. The ACTH receptor, also known as the melanocortin 2 receptor (MC2R), is unusual in that it...

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Clark AJ, Forfar R, Hussain M, et al. ACTH Antagonists. Front Endocrinol (Lausanne). 2016;7:101doi: 10.3389/fendo.2016.00101.
Clark, A. J., Forfar, R., Hussain, M., Jerman, J., McIver, E., Taylor, D., & Chan, L. (2016). ACTH Antagonists. Frontiers in endocrinology, 7101. https://doi.org/10.3389/fendo.2016.00101
Clark, Adrian John, et al. "ACTH Antagonists." Frontiers in endocrinology vol. 7 (2016): 101. doi: https://doi.org/10.3389/fendo.2016.00101
Clark AJ, Forfar R, Hussain M, Jerman J, McIver E, Taylor D, Chan L. ACTH Antagonists. Front Endocrinol (Lausanne). 2016 Aug 05;7:101. doi: 10.3389/fendo.2016.00101. eCollection 2016. PMID: 27547198; PMCID: PMC4974254.
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Probing the Structure, Dynamics, and Bonding of Coinage Metal Complexes of White Phosphorus.

Chemistry (Weinheim an der Bergstrasse, Germany)

Forfar LC, Zeng D, Green M, McGrady JE, Russell CA.
PMID: 26918670
Chemistry. 2016 Apr 04;22(15):5397-403. doi: 10.1002/chem.201505031. Epub 2016 Feb 25.

A series of cationic white phosphorus complexes of the coinage metals Au and Cu have been synthesised and characterised both in the solid state and in solution. All complexes feature a P4 unit coordinated through an edge P-P vector...

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Forfar LC, Zeng D, Green M, et al. Probing the Structure, Dynamics, and Bonding of Coinage Metal Complexes of White Phosphorus. Chemistry. 2016;22(15):5397-403doi: 10.1002/chem.201505031.
Forfar, L. C., Zeng, D., Green, M., McGrady, J. E., & Russell, C. A. (2016). Probing the Structure, Dynamics, and Bonding of Coinage Metal Complexes of White Phosphorus. Chemistry (Weinheim an der Bergstrasse, Germany), 22(15), 5397-403. https://doi.org/10.1002/chem.201505031
Forfar, Laura C, et al. "Probing the Structure, Dynamics, and Bonding of Coinage Metal Complexes of White Phosphorus." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 22,15 (2016): 5397-403. doi: https://doi.org/10.1002/chem.201505031
Forfar LC, Zeng D, Green M, McGrady JE, Russell CA. Probing the Structure, Dynamics, and Bonding of Coinage Metal Complexes of White Phosphorus. Chemistry. 2016 Apr 04;22(15):5397-403. doi: 10.1002/chem.201505031. Epub 2016 Feb 25. PMID: 26918670.
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