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Showing 1 to 12 of 38 entries
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Structure and rheology of cetomacrogol creams: the influence of alcohol chain length and homologue composition.

The Journal of pharmacy and pharmacology

Eccleston GM.
PMID: 15080
J Pharm Pharmacol. 1977 Mar;29(3):157-62. doi: 10.1111/j.2042-7158.1977.tb11274.x.

Liquid paraffin-in-water emulsions prepared with cetomacrogol 1000 and alcohols cetostearyl (A), cetyl (B), steryl (C) and myristyl (D) were examined by microscopical, particle size analytical and rheological (continuous shear, small strain creep, and oscillation) techniques at 25 degrees as...

The influence of fatty alcohols on the structure and stability of creams prepared with polyethylene glycol 1000 monostearate/fatty alcohols.

International journal of cosmetic science

Eccleston GM.
PMID: 19469959
Int J Cosmet Sci. 1982 Aug;4(4):133-42. doi: 10.1111/j.1467-2494.1982.tb00309.x.

Synopsis Liquid paraffin in water emulsions stabilized by PEG 1000 monostearate and alcohols cetostearyl (c/s) myristyl (C(14)), cetyl (C(16)) or stearyl (C(18)) and ternary systems prepared by dispersing each fatty alcohol and surfactant in water were examined during 30...

Towards a correlation between drug properties and in vitro transdermal flux variability.

International journal of pharmaceutics

Frum Y, Khan GM, Sefcik J, Rouse J, Eccleston GM, Meidan VM.
PMID: 17182201
Int J Pharm. 2007 May 04;336(1):140-7. doi: 10.1016/j.ijpharm.2006.11.049. Epub 2006 Nov 28.

Over recent years, there has been growing evidence that the permeability coefficient variability describing any specific transdermal drug delivery system is not always normally distributed. However, since different researchers have used different test compounds, methodologies and skin types, it...

Lyophilised wafers as a drug delivery system for wound healing containing methylcellulose as a viscosity modifier.

International journal of pharmaceutics

Matthews KH, Stevens HN, Auffret AD, Humphrey MJ, Eccleston GM.
PMID: 15652198
Int J Pharm. 2005 Jan 31;289(1):51-62. doi: 10.1016/j.ijpharm.2004.10.022. Epub 2004 Dec 30.

Lyophilised wafers have potential as drug delivery systems for suppurating wounds. A dual series of wafers made from low molecular weight sodium alginate (SA) and xanthan gum (XG) respectively, modified with high molecular weight methylcellulose (MC) were produced. The...

Gamma-irradiation of lyophilised wound healing wafers.

International journal of pharmaceutics

Matthews KH, Stevens HN, Auffret AD, Humphrey MJ, Eccleston GM.
PMID: 16503387
Int J Pharm. 2006 Apr 26;313(1):78-86. doi: 10.1016/j.ijpharm.2006.01.023. Epub 2006 Feb 28.

Lyophilised wafers are being developed as drug delivery systems that can be applied directly to the surface of suppurating wounds. They are produced by the freeze-drying of polymer solutions and gels. This study investigates the possibility of sterilising these...

In-vitro permeation of drugs into porcine hair follicles: is it quantitatively equivalent to permeation into human hair follicles?.

The Journal of pharmacy and pharmacology

Frum Y, Eccleston GM, Meidan VM.
PMID: 18237461
J Pharm Pharmacol. 2008 Feb;60(2):145-51. doi: 10.1211/jpp.60.2.0002.

It is already well-established that the general permeability properties of porcine skin are close to those of human skin. However, very little is known with respect to drug absorption into hair follicles and the similarities if any between the...

Evidence that drug flux across synthetic membranes is described by normally distributed permeability coefficients.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Frum Y, Eccleston GM, Meidan VM.
PMID: 17459683
Eur J Pharm Biopharm. 2007 Sep;67(2):434-9. doi: 10.1016/j.ejpb.2007.03.012. Epub 2007 Mar 18.

Over recent decades, the use of in vitro diffusion cell studies to assess skin permeability has evolved into a major research tool, providing key insights into the relationships between skin, drug and formulation. Sometimes, such studies involve synthetic membranes...

Formulation, stability and thermal analysis of lyophilised wound healing wafers containing an insoluble MMP-3 inhibitor and a non-ionic surfactant.

International journal of pharmaceutics

Matthews KH, Stevens HN, Auffret AD, Humphrey MJ, Eccleston GM.
PMID: 18280068
Int J Pharm. 2008 May 22;356(1):110-20. doi: 10.1016/j.ijpharm.2007.12.043. Epub 2008 Jan 09.

Lyophilised wafers are being developed as topical drug delivery systems for the treatment of chronic wounds. This study describes the formulation of xanthan wafers containing a selective, insoluble MMP-3 inhibitor (UK-370,106) and a non-ionic surfactant, designed to release accurate...

Structure and rheology of semisolid o/w creams containing cetyl alcohol/non-ionic surfactant mixed emulsifier and different polymers.

International journal of cosmetic science

Ribeiro HM, Morais JA, Eccleston GM.
PMID: 18494913
Int J Cosmet Sci. 2004 Apr;26(2):47-59. doi: 10.1111/j.0412-5463.2004.00190.x.

Oil-in-water (o/w) emulsions for cosmetic use, such as lotions and creams, are complex multiple-phase systems, which may contain a number of interacting surfactants, fatty amphiphiles, polymers and other excipients. This study investigates the influence of two synthetic cationic polymers,...

Development and mechanical characterization of solvent-cast polymeric films as potential drug delivery systems to mucosal surfaces.

Drug development and industrial pharmacy

Boateng JS, Stevens HN, Eccleston GM, Auffret AD, Humphrey MJ, Matthews KH.
PMID: 19365780
Drug Dev Ind Pharm. 2009 Aug;35(8):986-96. doi: 10.1080/03639040902744704.

Solvent-cast films from three polymers, carboxymethylcellulose (CMC), sodium alginate (SA), and xanthan gum, were prepared by drying the polymeric gels in air. Three methods, (a) passive hydration, (b) vortex hydration with heating, and (c) cold hydration, were investigated to...

Oscillatory testing of o-w emulsions containing mixed emulsifiers of the surfactant-long chain alcohol type: influence of surfactant chain length.

The Journal of pharmacy and pharmacology

Barry BW, Eccleston GM.
PMID: 4146395
J Pharm Pharmacol. 1973 May;25(5):394-400. doi: 10.1111/j.2042-7158.1973.tb10034.x.

No abstract available.

Oscillatory testing of o-w emulsions containing mixed emulsifers of the surfactant-long chain alcohol type: self-bodying action.

The Journal of pharmacy and pharmacology

Barry BW, Eccleston GM.
PMID: 4146325
J Pharm Pharmacol. 1973 Mar;25(3):244-53.

No abstract available.

Showing 1 to 12 of 38 entries