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Showing 1 to 12 of 172 entries
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Belgian consensus on metabolic problems associated with atypical antipsychotics.

International journal of psychiatry in clinical practice

De Nayer A, De Hert M, Scheen A, Van Gaal L, Peuskens J, On Behalf Of The Consensus Group, De Nayer A, De Hert M, Scheen A, Van Gaal L, Peuskens J, On Behalf Of The Consensus Group.
PMID: 24930795
Int J Psychiatry Clin Pract. 2005;9(2):130-7. doi: 10.1080/13651500510018310.

A workshop was convened by a panel of psychiatrists, diabetologists and pharmacists from major Belgian hospitals to review the latest information relating to the risks with second-generation antipsychotics (SGA) for the development of metabolic disorders, especially impaired glucose tolerance,...

Preconception sex selection for non-medical and intermediate reasons: ethical reflections.

Facts, views & vision in ObGyn

de Wert G, Dondorp W.
PMID: 25009714
Facts Views Vis Obgyn. 2010;2(4):267-77.

Sex selection for non-medical reasons is forbidden in many countries. Focusing on preconception sex selection, the authors first observe that it is unclear what should count as a 'medical reason' in this context and argue for the existence of...

Schizophrenia and the risk of fractures: a systematic review and comparative meta-analysis.

General hospital psychiatry

Stubbs B, Gaughran F, Mitchell AJ, De Hert M, Farmer R, Soundy A, Rosenbaum S, Vancampfort D.
PMID: 25666994
Gen Hosp Psychiatry. 2015 Mar-Apr;37(2):126-33. doi: 10.1016/j.genhosppsych.2015.01.004. Epub 2015 Jan 15.

BACKGROUND: People with schizophrenia experience increased rates of osteoporosis and may be at heightened risk of fractures. We conducted a systematic review and meta-analysis to investigate fractures among people with schizophrenia compared to people without mental illness.METHOD: We systematically...

Pairwise H.

Journal of the American Chemical Society

Manz DH, Duan PC, Dechert S, Demeshko S, Oswald R, John M, Mata RA, Meyer F.
PMID: 29037034
J Am Chem Soc. 2017 Nov 22;139(46):16720-16731. doi: 10.1021/jacs.7b08629. Epub 2017 Nov 07.

A compartmental ligand scaffold HL with two β-diketiminato binding sites spanned by a pyrazolate bridge gave a series of dinuclear nickel(II) dihydride complexes M[LNi

Complete Series of {FeNO}(8), {FeNO}(7), and {FeNO}(6) Complexes Stabilized by a Tetracarbene Macrocycle.

Journal of the American Chemical Society

Kupper C, Rees JA, Dechert S, DeBeer S, Meyer F.
PMID: 27191681
J Am Chem Soc. 2016 Jun 29;138(25):7888-98. doi: 10.1021/jacs.6b00584. Epub 2016 Jun 20.

Use of a macrocyclic tetracarbene ligand, which is topologically reminiscent of tetrapyrrole macrocycles though electronically distinct, has allowed for the isolation, X-ray crystallographic characterization and comprehensive spectroscopic investigation of a complete set of {FeNO}(x) complexes (x = 6, 7,...

Diabetes mellitus in people with schizophrenia, bipolar disorder and major depressive disorder: a systematic review and large scale meta-analysis.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Vancampfort D, Correll CU, Galling B, Probst M, De Hert M, Ward PB, Rosenbaum S, Gaughran F, Lally J, Stubbs B.
PMID: 27265707
World Psychiatry. 2016 Jun;15(2):166-74. doi: 10.1002/wps.20309.

Type 2 diabetes mellitus (T2DM) is highly predictive of cardiovascular diseases and can have particularly deleterious health impacts in people with severe mental illness (SMI), i.e. schizophrenia, bipolar disorder or major depressive disorder. This meta-analysis aimed: a) to describe...

Recent advances in cerebral oximetry. Assessment of cerebral autoregulation with near-infrared spectroscopy: myth or reality?.

F1000Research

Moerman A, De Hert S.
PMID: 29026526
F1000Res. 2017 Aug 31;6:1615. doi: 10.12688/f1000research.11351.1. eCollection 2017.

In recent years, the feasibility of near-infrared spectroscopy to continuously assess cerebral autoregulation has gained increasing interest. By plotting cerebral oxygen saturation over blood pressure, clinicians can generate an index of autoregulation: the cerebral oximetry index (COx). Successful integration...

Spin Crossover in Fe(II)-M(II) Cyanoheterobimetallic Frameworks (M = Ni, Pd, Pt) with 2-Substituted Pyrazines.

Inorganic chemistry

Kucheriv OI, Shylin SI, Ksenofontov V, Dechert S, Haukka M, Fritsky IO, Gural'skiy IA.
PMID: 27120049
Inorg Chem. 2016 May 16;55(10):4906-14. doi: 10.1021/acs.inorgchem.6b00446. Epub 2016 Apr 27.

Discovery of spin-crossover (SCO) behavior in the family of Fe(II)-based Hofmann clathrates has led to a "new rush" in the field of bistable molecular materials. To date this class of SCO complexes is represented by several dozens of individual...

Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Correll CU, Detraux J, De Lepeleire J, De Hert M.
PMID: 26043321
World Psychiatry. 2015 Jun;14(2):119-36. doi: 10.1002/wps.20204.

People with severe mental illness have a considerably shorter lifespan than the general population. This excess mortality is mainly due to physical illness. Next to mental illness-related factors, unhealthy lifestyle, and disparities in health care access and utilization, psychotropic...

Responsible implementation of expanded carrier screening.

European journal of human genetics : EJHG

Henneman L, Borry P, Chokoshvili D, Cornel MC, van El CG, Forzano F, Hall A, Howard HC, Janssens S, Kayserili H, Lakeman P, Lucassen A, Metcalfe SA, Vidmar L, de Wert G, Dondorp WJ, Peterlin B.
PMID: 29023436
Eur J Hum Genet. 2017 Nov;25(11):1291. doi: 10.1038/ejhg.2017.159.

This corrects the article DOI: 10.1038/ejhg.2015.271.

Lifestyle Vaccines and Public Health: Exploring Policy Options for a Vaccine to Stop Smoking.

Public health ethics

Wolters A, de Wert G, van Schayck OC, Horstman K.
PMID: 27551304
Public Health Ethics. 2016 Jul;9(2):183-197. doi: 10.1093/phe/phw004. Epub 2016 Mar 14.

Experimental vaccines are being developed for the treatment of 'unhealthy lifestyles' and associated chronic illnesses. Policymakers and other stakeholders will have to deal with the ethical issues that this innovation path raises: are there morally justified reasons to integrate...

Ligand Rearrangements at Fe/S Cofactors: Slow Isomerization of a Biomimetic [2Fe-2S] Cluster.

Angewandte Chemie (International ed. in English)

Bergner M, Roy L, Dechert S, Neese F, Ye S, Meyer F.
PMID: 28370980
Angew Chem Int Ed Engl. 2017 Apr 18;56(17):4882-4886. doi: 10.1002/anie.201612621. Epub 2017 Mar 30.

Ligand exchange plays an important role in the biogenesis of Fe/S clusters, most prominently during cluster transfer from a scaffold protein to its target protein. Although in vivo and in vitro studies have provided some insight into this process,...

Showing 1 to 12 of 172 entries