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Showing 1 to 12 of 24 entries
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Genetic learning automata for function optimization.

IEEE transactions on systems, man, and cybernetics. Part B, Cybernetics : a publication of the IEEE Systems, Man, and Cybernetics Society

Howell MN, Gordon TJ, Brandao FV.
PMID: 18244886
IEEE Trans Syst Man Cybern B Cybern. 2002;32(6):804-15. doi: 10.1109/TSMCB.2002.1049614.

Stochastic learning automata and genetic algorithms (GAs) have previously been shown to have valuable global optimization properties. Learning automata have, however, been criticized for having a relatively slow rate of convergence. In this paper, these two techniques are combined...

A trisheteroleptic cyclometalated Ru(II) sensitizer that enables high power output in a dye-sensitized solar cell.

Angewandte Chemie (International ed. in English)

Bomben PG, Gordon TJ, Schott E, Berlinguette CP.
PMID: 22002866
Angew Chem Int Ed Engl. 2011 Nov 04;50(45):10682-5. doi: 10.1002/anie.201104275. Epub 2011 Aug 30.

No abstract available.

An eEF1A1 truncation encoded by PTI-1 exerts its oncogenic effect inside the nucleus.

Cancer cell international

Dahl LD, Corydon TJ, Ränkel L, Nielsen KM, Füchtbauer EM, Knudsen CR.
PMID: 24571548
Cancer Cell Int. 2014 Feb 26;14(1):17. doi: 10.1186/1475-2867-14-17.

BACKGROUND: The oncogene PTI-1 was originally isolated from a prostate cancer cell line by its capability to transform rat fibroblasts. The PTI-1 mRNA has a very eccentric structure as the 5'UTR is similar to prokaryotic 23S rRNA, while the...

Clinical calculations.

Nursing

Cordon MJ.
PMID: 2046998
Nursing. 1991 Jun;21(6):77-8.

No abstract available.

Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein.

Molecular therapy. Nucleic acids

Dalsgaard T, Cecchi CR, Askou AL, Bak RO, Andersen PO, Hougaard D, Jensen TG, Dagnæs-Hansen F, Mikkelsen JG, Corydon TJ, Aagaard L.
PMID: 30092403
Mol Ther Nucleic Acids. 2018 Sep 07;12:672-683. doi: 10.1016/j.omtn.2018.07.005. Epub 2018 Aug 06.

Delivery of genes to mouse liver is routinely accomplished by tail-vein injections of viral vectors or naked plasmid DNA. While viral vectors are typically injected in a low-pressure and -volume fashion, uptake of naked plasmid DNA to hepatocytes is...

Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors.

Molecular therapy. Methods & clinical development

Askou AL, Aagaard L, Kostic C, Arsenijevic Y, Hollensen AK, Bek T, Jensen TG, Mikkelsen JG, Corydon TJ.
PMID: 26052532
Mol Ther Methods Clin Dev. 2015 Jan 28;2:14064. doi: 10.1038/mtm.2014.64. eCollection 2015.

Lentivirus-based gene delivery vectors carrying multiple gene cassettes are powerful tools in gene transfer studies and gene therapy, allowing coexpression of multiple therapeutic factors and, if desired, fluorescent reporters. Current strategies to express transgenes and microRNA (miRNA) clusters from...

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine.

Frontiers in cell and developmental biology

Sahana J, Corydon TJ, Wehland M, Krüger M, Kopp S, Melnik D, Kahlert S, Relja B, Infanger M, Grimm D.
PMID: 34277614
Front Cell Dev Biol. 2021 Jun 30;9:672098. doi: 10.3389/fcell.2021.672098. eCollection 2021.

In this study, we evaluated changes in focal adhesions (FAs) in two types of breast cancer cell (BCC) lines (differentiated MCF-7 and the triple-negative MDA-MB-231 cell line) exposed to simulated microgravity (s-μ

Changes in Exosomal miRNA Composition in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space.

International journal of molecular sciences

Wise PM, Neviani P, Riwaldt S, Corydon TJ, Wehland M, Braun M, Krüger M, Infanger M, Grimm D.
PMID: 34884646
Int J Mol Sci. 2021 Nov 27;22(23). doi: 10.3390/ijms222312841.

As much as space travel and exploration have been a goal since humankind looked up to the stars, the challenges coming with it are manifold and difficult to overcome. Therefore, researching the changes the human organism undergoes following exposure...

Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells.

Frontiers in cellular neuroscience

Fisher F, Zhang Y, Vincent PFY, Gajewiak J, Gordon TJ, Glowatzki E, Fuchs PA, McIntosh JM.
PMID: 34385908
Front Cell Neurosci. 2021 Jul 23;15:697560. doi: 10.3389/fncel.2021.697560. eCollection 2021.

Efferent cholinergic neurons inhibit sensory hair cells of the vertebrate inner ear through the combined action of calcium-permeable α9α10-containing nicotinic acetylcholine receptors (nAChRs) and associated calcium-dependent potassium channels. The venom of cone snails is a rich repository of bioactive...

Effects of a Mutation in the .

Frontiers in molecular biosciences

Bie AS, Fernandez-Guerra P, Birkler RI, Nisemblat S, Pelnena D, Lu X, Deignan JL, Lee H, Dorrani N, Corydon TJ, Palmfeldt J, Bivina L, Azem A, Herman K, Bross P.
PMID: 27774450
Front Mol Biosci. 2016 Oct 07;3:65. doi: 10.3389/fmolb.2016.00065. eCollection 2016.

We here report molecular investigations of a missense mutation in the

Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules.

BMC research notes

Larsen J, Pettersson OJ, Jakobsen M, Thomsen R, Pedersen CB, Hertz JM, Gregersen N, Corydon TJ, Jensen TG, Potts J.
PMID: 22078098
BMC Res Notes. 2011 Nov 11;4:490. doi: 10.1186/1756-0500-4-490.

BACKGROUND: Myotonic dystrophy type 1 (DM1) is the most common muscle dystrophy in adults. The disease is caused by a triplet expansion in the 3'end of the myotonic dystrophy protein kinase (DMPK) gene. In order to develop a human...

Dominant Role of Entropy in Stabilizing Sugar Isomerization Transition States within Hydrophobic Zeolite Pores.

Journal of the American Chemical Society

Cordon MJ, Harris JW, Vega-Vila JC, Bates JS, Kaur S, Gupta M, Witzke ME, Wegener EC, Miller JT, Flaherty DW, Hibbitts DD, Gounder R.
PMID: 30265002
J Am Chem Soc. 2018 Oct 31;140(43):14244-14266. doi: 10.1021/jacs.8b08336. Epub 2018 Oct 19.

Lewis acid sites in zeolites catalyze aqueous-phase sugar isomerization at higher turnover rates when confined within hydrophobic rather than within hydrophilic micropores; however, relative contributions of competitive water adsorption at active sites and preferential stabilization of isomerization transition states...

Showing 1 to 12 of 24 entries