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Introducing educational interventions for first year medical students in the area of cancer clinical trials: impact on attitudes and confidence

Educational trials

Mitschke DB.
GSID: F0VW8VsOGYQJ
DB Mitschke, RT Kasuya, K Cassel… - Journal of Cancer …, 2009 - Springer

… multi-faceted educational intervention designed to increase medical students’ confidence in discussing cancer clinical trials with patients. … confidence levels; however, these results were tempered with declines in attitudes related to clinical trials. Conclusions. Integrating clinical …

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Mitschke, D. B., Kasuya, R. T., Cassel, K., & Barcia, A. M. (2009). Introducing educational interventions for first year medical students in the area of cancer clinical trials: impact on attitudes and confidence. Journal of Cancer Education, 24(3), 212-217.
Mitschke, Diane B., et al. "Introducing educational interventions for first year medical students in the area of cancer clinical trials: impact on attitudes and confidence." Journal of Cancer Education 24.3 (2009): 212-217.
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Adherence to medication

interventions

Blaschke T.
GSID: 115KRPppTDYJ
L Osterberg, T Blaschke - New England journal of medicine, 2005 - Mass Medical Soc

The full benefit of many effective medications will be achieved only if patients adhere to prescribed treatment regimens. Unfortunately, applying terms such as “noncompliant” and …

[Current problems of pharmacotherapy. II. On the possibilities and limitations of drug therapy].

Das Deutsche Gesundheitswesen

Brüschke G, Oehme P.
PMID: 5584378
Dtsch Gesundheitsw. 1967 Jan 05;22(1):15-9.

No abstract available.

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Brüschke G, Oehme P. Aktuelle Probleme der Pharmakotherapie. II. Uber Möglichkeiten und Grenzen der Pharmakotherapie. [Current problems of pharmacotherapy. II. On the possibilities and limitations of drug therapy]. Dtsch Gesundheitsw. 1967;22(1):15-9
Brüschke, G., & Oehme, P. (1967). Aktuelle Probleme der Pharmakotherapie. II. Uber Möglichkeiten und Grenzen der Pharmakotherapie. [Current problems of pharmacotherapy. II. On the possibilities and limitations of drug therapy]. Das Deutsche Gesundheitswesen, 22(1), 15-9.
Brüschke, G, and Oehme, P. "Aktuelle Probleme der Pharmakotherapie. II. Uber Möglichkeiten und Grenzen der Pharmakotherapie." [Current problems of pharmacotherapy. II. On the possibilities and limitations of drug therapy]. Das Deutsche Gesundheitswesen vol. 22,1 (1967): 15-9.
Brüschke G, Oehme P. Aktuelle Probleme der Pharmakotherapie. II. Uber Möglichkeiten und Grenzen der Pharmakotherapie. [Current problems of pharmacotherapy. II. On the possibilities and limitations of drug therapy]. Dtsch Gesundheitsw. 1967 Jan 05;22(1):15-9. German. PMID: 5584378.
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[Current problems of pharmacotherapy. I. The scientific evaluation of clinical pharmacotherapy].

Das Deutsche Gesundheitswesen

Brüschke G, Oehme P.
PMID: 5977971
Dtsch Gesundheitsw. 1966 Dec 22;21(51):2419-23.

No abstract available.

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Brüschke G, Oehme P. Aktuelle Probleme der Pharmakotherapie. I. Die wissenschaftliche Beurteilung der klinischen Pharmakotherapie. [Current problems of pharmacotherapy. I. The scientific evaluation of clinical pharmacotherapy]. Dtsch Gesundheitsw. 1966;21(51):2419-23
Brüschke, G., & Oehme, P. (1966). Aktuelle Probleme der Pharmakotherapie. I. Die wissenschaftliche Beurteilung der klinischen Pharmakotherapie. [Current problems of pharmacotherapy. I. The scientific evaluation of clinical pharmacotherapy]. Das Deutsche Gesundheitswesen, 21(51), 2419-23.
Brüschke, G, and Oehme, P. "Aktuelle Probleme der Pharmakotherapie. I. Die wissenschaftliche Beurteilung der klinischen Pharmakotherapie." [Current problems of pharmacotherapy. I. The scientific evaluation of clinical pharmacotherapy]. Das Deutsche Gesundheitswesen vol. 21,51 (1966): 2419-23.
Brüschke G, Oehme P. Aktuelle Probleme der Pharmakotherapie. I. Die wissenschaftliche Beurteilung der klinischen Pharmakotherapie. [Current problems of pharmacotherapy. I. The scientific evaluation of clinical pharmacotherapy]. Dtsch Gesundheitsw. 1966 Dec 22;21(51):2419-23. German. PMID: 5977971.
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Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency.

Journal of tissue engineering

Rennert K, Nitschke M, Wallert M, Keune N, Raasch M, Lorkowski S, Mosig AS.
PMID: 28890781
J Tissue Eng. 2017 Aug 25;8:2041731417726428. doi: 10.1177/2041731417726428. eCollection 2017.

Harvesting cultivated macrophages for tissue engineering purposes by enzymatic digestion of cell adhesion molecules can potentially result in unintended activation, altered function, or behavior of these cells. Thermo-responsive polymer is a promising tool that allows for gentle macrophage detachment...

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Rennert K, Nitschke M, Wallert M, et al. Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency. J Tissue Eng. 2017;8:2041731417726428doi: 10.1177/2041731417726428.
Rennert, K., Nitschke, M., Wallert, M., Keune, N., Raasch, M., Lorkowski, S., & Mosig, A. S. (2017). Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency. Journal of tissue engineering, 82041731417726428. https://doi.org/10.1177/2041731417726428
Rennert, Knut, et al. "Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency." Journal of tissue engineering vol. 8 (2017): 2041731417726428. doi: https://doi.org/10.1177/2041731417726428
Rennert K, Nitschke M, Wallert M, Keune N, Raasch M, Lorkowski S, Mosig AS. Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency. J Tissue Eng. 2017 Aug 25;8:2041731417726428. doi: 10.1177/2041731417726428. eCollection 2017. PMID: 28890781; PMCID: PMC5574476.
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Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity.

Journal of clinical and translational research

Xie Y, Woolbright BL, Kos M, McGill MR, Dorko K, Kumer SC, Schmitt TM, Jaeschke H.
PMID: 26722668
J Clin Transl Res. 2015;1(2):100-106. doi: 10.18053/jctres.201502.004. Epub 2015 Sep 30.

BACKGROUND: Acetaminophen (APAP) hepatotoxicity is a major cause of acute liver failure in many countries. Mechanistic studies in mice and humans have implicated formation of a reactive metabolite, mitochondrial dysfunction and oxidant stress as critical events in the pathophysiology...

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Xie Y, Woolbright BL, Kos M, et al. Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity. J Clin Transl Res. 2015;1(2):100-106doi: 10.18053/jctres.201502.004.
Xie, Y., Woolbright, B. L., Kos, M., McGill, M. R., Dorko, K., Kumer, S. C., Schmitt, T. M., & Jaeschke, H. (2015). Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity. Journal of clinical and translational research, 1(2), 100-106. https://doi.org/10.18053/jctres.201502.004
Xie, Yuchao, et al. "Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity." Journal of clinical and translational research vol. 1,2 (2015): 100-106. doi: https://doi.org/10.18053/jctres.201502.004
Xie Y, Woolbright BL, Kos M, McGill MR, Dorko K, Kumer SC, Schmitt TM, Jaeschke H. Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity. J Clin Transl Res. 2015;1(2):100-106. doi: 10.18053/jctres.201502.004. Epub 2015 Sep 30. PMID: 26722668; PMCID: PMC4694640.
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[Correction: Dyspnea].

Der Internist

Hauswaldt J, Blaschke S.
PMID: 29124301
Internist (Berl). 2018 Jan;59(1):104. doi: 10.1007/s00108-017-0349-2.

No abstract available.

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Hauswaldt J, Blaschke S. Correction: Dyspnoe. [Correction: Dyspnea]. Internist (Berl). 2018;59(1):104doi: 10.1007/s00108-017-0349-2.
Hauswaldt, J., & Blaschke, S. (2018). Correction: Dyspnoe. [Correction: Dyspnea]. Der Internist, 59(1), 104. https://doi.org/10.1007/s00108-017-0349-2
Hauswaldt, J, and Blaschke, S. "Correction: Dyspnoe." [Correction: Dyspnea]. Der Internist vol. 59,1 (2018): 104. doi: https://doi.org/10.1007/s00108-017-0349-2
Hauswaldt J, Blaschke S. Correction: Dyspnoe. [Correction: Dyspnea]. Internist (Berl). 2018 Jan;59(1):104. doi: 10.1007/s00108-017-0349-2. German. PMID: 29124301.
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The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis.

Obesity science & practice

Kalani A, Bami H, Tiboni M, Jaeschke R, Adachi JD, Lau AN.
PMID: 29071108
Obes Sci Pract. 2017 Jun 27;3(3):319-332. doi: 10.1002/osp4.113. eCollection 2017 Sep.

BACKGROUND: Concerns have emerged about post-operative decreases in calcium and vitamin D following bariatric surgery. This review explores changes in metabolic bone health in persons with obesity undergoing gastric bypass surgery compared to non-surgical controls, providing an updated and...

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Kalani A, Bami H, Tiboni M, et al. The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis. Obes Sci Pract. 2017;3(3):319-332doi: 10.1002/osp4.113.
Kalani, A., Bami, H., Tiboni, M., Jaeschke, R., Adachi, J. D., & Lau, A. N. (2017). The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis. Obesity science & practice, 3(3), 319-332. https://doi.org/10.1002/osp4.113
Kalani, A, et al. "The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis." Obesity science & practice vol. 3,3 (2017): 319-332. doi: https://doi.org/10.1002/osp4.113
Kalani A, Bami H, Tiboni M, Jaeschke R, Adachi JD, Lau AN. The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis. Obes Sci Pract. 2017 Jun 27;3(3):319-332. doi: 10.1002/osp4.113. eCollection 2017 Sep. PMID: 29071108; PMCID: PMC5598026.
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Molecular de-novo design through deep reinforcement learning.

Journal of cheminformatics

Olivecrona M, Blaschke T, Engkvist O, Chen H.
PMID: 29086083
J Cheminform. 2017 Sep 04;9(1):48. doi: 10.1186/s13321-017-0235-x.

This work introduces a method to tune a sequence-based generative model for molecular de novo design that through augmented episodic likelihood can learn to generate structures with certain specified desirable properties. We demonstrate how this model can execute a...

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Olivecrona M, Blaschke T, Engkvist O, et al. Molecular de-novo design through deep reinforcement learning. J Cheminform. 2017;9(1):48doi: 10.1186/s13321-017-0235-x.
Olivecrona, M., Blaschke, T., Engkvist, O., & Chen, H. (2017). Molecular de-novo design through deep reinforcement learning. Journal of cheminformatics, 9(1), 48. https://doi.org/10.1186/s13321-017-0235-x
Olivecrona, Marcus, et al. "Molecular de-novo design through deep reinforcement learning." Journal of cheminformatics vol. 9,1 (2017): 48. doi: https://doi.org/10.1186/s13321-017-0235-x
Olivecrona M, Blaschke T, Engkvist O, Chen H. Molecular de-novo design through deep reinforcement learning. J Cheminform. 2017 Sep 04;9(1):48. doi: 10.1186/s13321-017-0235-x. PMID: 29086083; PMCID: PMC5583141.
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Phase separation and coexistence of hydrodynamically interacting microswimmers.

Soft matter

Blaschke J, Maurer M, Menon K, Zöttl A, Stark H.
PMID: 27869284
Soft Matter. 2016 Dec 06;12(48):9821-9831. doi: 10.1039/c6sm02042a.

A striking feature of the collective behavior of spherical microswimmers is that for sufficiently strong self-propulsion they phase-separate into a dense cluster coexisting with a low-density disordered surrounding. Extending our previous work, we use the squirmer as a model...

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Blaschke J, Maurer M, Menon K, et al. Phase separation and coexistence of hydrodynamically interacting microswimmers. Soft Matter. 2016;12(48):9821-9831doi: 10.1039/c6sm02042a.
Blaschke, J., Maurer, M., Menon, K., Zöttl, A., & Stark, H. (2016). Phase separation and coexistence of hydrodynamically interacting microswimmers. Soft matter, 12(48), 9821-9831. https://doi.org/10.1039/c6sm02042a
Blaschke, Johannes, et al. "Phase separation and coexistence of hydrodynamically interacting microswimmers." Soft matter vol. 12,48 (2016): 9821-9831. doi: https://doi.org/10.1039/c6sm02042a
Blaschke J, Maurer M, Menon K, Zöttl A, Stark H. Phase separation and coexistence of hydrodynamically interacting microswimmers. Soft Matter. 2016 Dec 06;12(48):9821-9831. doi: 10.1039/c6sm02042a. PMID: 27869284.
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Catenation and encapsulation induce distinct reconstitutions within a dynamic library of mixed-ligand Zn.

Chemical science

Black SP, Wood DM, Schwarz FB, Ronson TK, Holstein JJ, Stefankiewicz AR, Schalley CA, Sanders JKM, Nitschke JR.
PMID: 28660033
Chem Sci. 2016 Apr 21;7(4):2614-2620. doi: 10.1039/c5sc04906g. Epub 2016 Jan 22.

Two new Zn

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Black SP, Wood DM, Schwarz FB, et al. Catenation and encapsulation induce distinct reconstitutions within a dynamic library of mixed-ligand Zn. Chem Sci. 2016;7(4):2614-2620doi: 10.1039/c5sc04906g.
Black, S. P., Wood, D. M., Schwarz, F. B., Ronson, T. K., Holstein, J. J., Stefankiewicz, A. R., Schalley, C. A., Sanders, J. K. M., & Nitschke, J. R. (2016). Catenation and encapsulation induce distinct reconstitutions within a dynamic library of mixed-ligand Zn. Chemical science, 7(4), 2614-2620. https://doi.org/10.1039/c5sc04906g
Black, Samuel P, et al. "Catenation and encapsulation induce distinct reconstitutions within a dynamic library of mixed-ligand Zn." Chemical science vol. 7,4 (2016): 2614-2620. doi: https://doi.org/10.1039/c5sc04906g
Black SP, Wood DM, Schwarz FB, Ronson TK, Holstein JJ, Stefankiewicz AR, Schalley CA, Sanders JKM, Nitschke JR. Catenation and encapsulation induce distinct reconstitutions within a dynamic library of mixed-ligand Zn. Chem Sci. 2016 Apr 21;7(4):2614-2620. doi: 10.1039/c5sc04906g. Epub 2016 Jan 22. PMID: 28660033; PMCID: PMC5477050.
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Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.

Journal of clinical and translational research

Ramachandran A, Jaeschke H.
PMID: 28670625
J Clin Transl Res. 2017 Feb;3:157-169. doi: 10.18053/jctres.03.2017S1.002. Epub 2017 Feb 12.

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely...

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Ramachandran A, Jaeschke H. Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology. J Clin Transl Res. 2017;3:157-169doi: 10.18053/jctres.03.2017S1.002.
Ramachandran, A., & Jaeschke, H. (2017). Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology. Journal of clinical and translational research, 3157-169. https://doi.org/10.18053/jctres.03.2017S1.002
Ramachandran, Anup, and Jaeschke, Hartmut. "Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology." Journal of clinical and translational research vol. 3 (2017): 157-169. doi: https://doi.org/10.18053/jctres.03.2017S1.002
Ramachandran A, Jaeschke H. Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology. J Clin Transl Res. 2017 Feb;3:157-169. doi: 10.18053/jctres.03.2017S1.002. Epub 2017 Feb 12. PMID: 28670625; PMCID: PMC5489132.
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