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Showing 1 to 12 of 3398 entries
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DNA damage response proteins synergistically affect the cancer prognosis and resistance.

Free radical biology & medicine

Sharma M, Anand P, Padwad YS, Dogra V, Acharya V.
PMID: 34848370
Free Radic Biol Med. 2021 Nov 27;178:174-188. doi: 10.1016/j.freeradbiomed.2021.11.033. Epub 2021 Nov 27.

Amplification of oxidative stress can be utilized as a strategy to attenuate cancer progression by instigating apoptosis. However, the duration of positive response to such therapies is limited, as cancer cells eventually develop resistance. The underlying molecular mechanisms of...

Ipsilateral floating hip and knee, or floating lower limb - A rare case report.

Trauma case reports

Anand V, Deviprasad, Praba K, Babar S, Babu M.
PMID: 33365379
Trauma Case Rep. 2020 Dec 10;31:100390. doi: 10.1016/j.tcr.2020.100390. eCollection 2021 Feb.

INTRODUCTION: Ipsilateral floating hip and knee injuries at the same time are very rare injuries, occurring due to high velocity trauma. With a small number of such case reports, the treatment guidelines regarding surgical fixation are yet to be...

Immunological characterization of rLdTCP1γ for its prophylactic potential against visceral leishmaniasis in hamster model.

Molecular immunology

Anand A, Balodi DC, Ramalingam K, Yadav S, Goyal N.
PMID: 34798496
Mol Immunol. 2021 Nov 16;141:33-42. doi: 10.1016/j.molimm.2021.11.009. Epub 2021 Nov 16.

Visceral leishmaniasis (VL) is a chronic tropical disease responsible for devastating epidemics worldwide. Though current treatment relies on drugs, the emergence of resistance, toxic side-effects, and strenuous administration has led to an ineffective remedy. Hence, vaccination remains an alternative...

Association of Sleep Apnea With Development and Behavior in Down Syndrome: A Prospective Clinical and Polysomnographic Study.

Pediatric neurology

Anand V, Shukla G, Gupta N, Gupta A, Sapra S, Gulati S, Pandey RM, Pandey S, Kabra M.
PMID: 33388546
Pediatr Neurol. 2021 Mar;116:7-13. doi: 10.1016/j.pediatrneurol.2020.10.007. Epub 2020 Nov 19.

BACKGROUND: The prevalence of sleep-disordered breathing is high in children with Down syndrome. Although the association between sleep-disordered breathing and developmental delay and behavioral abnormalities are proven among typically developing children, there are few such studies of children with...

Correction: Loaded Inter-set Stretching for Muscular Adaptations in Trained Males: Is the Hype Real?.

International journal of sports medicine

Wadhi T, Barakat C, Evangelista AL, Pearson JR, Anand AS, Morrison TEA, O'Sullivan J, Walters J, Souza EO.
PMID: 34583397
Int J Sports Med. 2021 Sep 28; doi: 10.1055/a-1643-7189. Epub 2021 Sep 28.

No abstract available.

Sleep Disorders in Individuals With High Risk for Diabetes in Indian Population.

Annals of neurosciences

Maity K, Nagarathna R, Anand A, Patil SS, Singh A, Rajesh SK, Ramesh L, Sridhar P, Thakur UK, Nagendra HR.
PMID: 34556958
Ann Neurosci. 2020 Jul;27(3):183-189. doi: 10.1177/0972753121998470. Epub 2021 Apr 24.

BACKGROUND: Sleep restores physiology and neurochemical components of our body and is essential for physical and mental health. Sleep disorders (SDs) are associated with insulin resistance and metabolic disorders. The association between SDs and diabetes needs to be understood...

Identification of TLR2 Signalling Mechanisms Which Contribute to Barrett's and Oesophageal Adenocarcinoma Disease Progression.

Cancers

Flis E, Barber G, Nulty C, Keogh B, McGuirk P, Anand A, O'Sullivan J, Quante M, Creagh EM.
PMID: 33922955
Cancers (Basel). 2021 Apr 25;13(9). doi: 10.3390/cancers13092065.

Chronic inflammation plays an important role in the pathogenesis of oesophageal adenocarcinoma (EAC) and its only known precursor, Barrett's oesophagus (BE). Recent studies have shown that oesophageal TLR2 levels increase from normal epithelium towards EAC. TLR2 signalling is therefore...

Bringing Patient Perspective to the Forefront of High-Value Care.

Academic medicine : journal of the Association of American Medical Colleges

Daigle ER, Anand R.
PMID: 33394649
Acad Med. 2021 Jan 01;96(1):11-12. doi: 10.1097/ACM.0000000000003769.

No abstract available.

Structure guided mutagenesis reveals the substrate determinants of guanine deaminase.

Journal of structural biology

Singh J, Gaded V, Bitra A, Anand R.
PMID: 34010666
J Struct Biol. 2021 Sep;213(3):107747. doi: 10.1016/j.jsb.2021.107747. Epub 2021 May 16.

Guanine deaminases (GDs) are essential enzymes that regulate the overall nucleobase pool. Since the deamination of guanine to xanthine results in the production of a mutagenic base, these enzymes have evolved to be very specific in nature. Surprisingly, they...

Infectious Myelopathies.

Seminars in neurology

Anand P.
PMID: 34010967
Semin Neurol. 2021 Jun;41(3):280-290. doi: 10.1055/s-0041-1725126. Epub 2021 May 19.

In the setting of both globalization and increasing use of immunosuppressive therapy, infectious myelopathies are an important cause of morbidity worldwide. Clinical spinal cord syndromes related to infection are varied, including transverse myelitis, acute flaccid paralysis related to anterior...

Metastasizing Ameloblastoma: A 10 Year Clinicopathological Review with an Insight Into Pathogenesis.

Head and neck pathology

Pandiar D, Anand R, Kamboj M, Narwal A, Shameena PM, Devi A.
PMID: 33394372
Head Neck Pathol. 2021 Sep;15(3):967-974. doi: 10.1007/s12105-020-01258-5. Epub 2021 Jan 04.

Ameloblastoma, a benign but locally aggressive odontogenic tumor, often demonstrates metastasis despite benign histological features and this variant is termed as metastasizing ameloblastoma (METAM). It was classified under the malignant category in the 2005 WHO but has been re-classified...

Immunological characterization of rLdTCP1γ for its prophylactic potential against visceral leishmaniasis in hamster model.

Molecular immunology

Anand A, Balodi DC, Ramalingam K, Yadav S, Goyal N, Rathinasabapathy G.
PMID: 34798496
Mol Immunol. 2021 Nov 16;141:33-42. doi: 10.1016/j.molimm.2021.11.009. Epub 2021 Nov 16.

Visceral leishmaniasis (VL) is a chronic tropical disease responsible for devastating epidemics worldwide. Though current treatment relies on drugs, the emergence of resistance, toxic side-effects, and strenuous administration has led to an ineffective remedy. Hence, vaccination remains an alternative...

Showing 1 to 12 of 3398 entries