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Showing 37 to 48 of 79 entries
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Model-independent definition of the initial volume of distribution of drugs in the body.

International journal of clinical pharmacology, therapy, and toxicology

Piotrovskii VK.
PMID: 3759276
Int J Clin Pharmacol Ther Toxicol. 1986 Aug;24(8):403-7.

Model-independent definition of the initial volume of distribution of drugs in the body as a limit of the ratio of the drug content in the body to its blood concentration with time from the start of drug administration tending...

Data analysis problems in the area of pharmacokinetics research.

Biometrics

Shah BK.
PMID: 1276365
Biometrics. 1976 Mar;32(1):145-57.

Of interest in compartment analysis is the estimation of kinetic first order rate constants and quantification of the amount of drug present in each compartment at every point in time. From the data pertaining to only one compartment, it...

[A multiple iteration program for determining global pharmacokinetic constants on a digital computer (author's transl)].

Arzneimittel-Forschung

Lücker PW.
PMID: 580758
Arzneimittelforschung. 1978;28(3):471-2.

A program for determining pharmacokinetic constants on the basis of multiple iterations is described. After obtaining values for tmax, cmax and kel by means of graphs, the program calculates all important constants as well as the Bateman function between...

[Iteration program for determining pharmacokinetic constants with a digital computer (author's transl)].

Arzneimittel-Forschung

Lücker PW.
PMID: 580053
Arzneimittelforschung. 1977;27(12):2371-2.

An iteration program is reported by which it will be possible to determine the constants k1 and y0 by the graphical constants tmax and k2. The program is designed for the desk-calculator HP 97. It makes a relatively exact...

Programmable solution for the Michaelis-Menten equation.

Drug intelligence & clinical pharmacy

Collier PS.
PMID: 6688219
Drug Intell Clin Pharm. 1983 Jul-Aug;17(7):559-60. doi: 10.1177/106002808301700720.

No abstract available.

Kinetics of pharmacologic effects.

Clinical pharmacology and therapeutics

Levy G.
PMID: 5937003
Clin Pharmacol Ther. 1966 May-Jun;7(3):362-72. doi: 10.1002/cpt196673362.

No abstract available.

Symbols in pharmacokinetics.

Journal of pharmacokinetics and biopharmaceutics

Rowland M, Tucker G.
PMID: 7252793
J Pharmacokinet Biopharm. 1980 Oct;8(5):497-507. doi: 10.1007/BF01059548.

To encourage uniformity in the presentation of pharmacokinetic data, a general nomenclature has been developed. The system has wide application. Flexibility is achieved through the use of general variables, constants, qualifying terms, and subscripts. Yet, through the use of...

Confidence intervals for pharmacokinetic parameters [proceedings].

British journal of pharmacology

House FR, Rogers HJ.
PMID: 638369
Br J Pharmacol. 1978 Mar;62(3):453P.
Free PMC Article

No abstract available.

[Model building in pharmacokinetics/Part I: General strategy (author's transl)].

Arzneimittel-Forschung

Bozler G, Heinzel G, Koss FW, Wolf M.
PMID: 577856
Arzneimittelforschung. 1977;27(4):897-900.

A repetitive cycle: hypothesis-experiment-analysis is typical for construction and evaluation of models in pharmacokinetics. A general strategy is outlined to meet the requirements of correct modelling, proper experimental design, careful experiments, valid parameter estimation and model identification.

Time-dependent kinetics. VI: Direct relationship between equations for drug levels during induction and those involving constant clearance.

Journal of pharmaceutical sciences

Levy RH, Dumain MS.
PMID: 458623
J Pharm Sci. 1979 Jul;68(7):934-6. doi: 10.1002/jps.2600680748.

No abstract available.

Whither drug distribution?.

Anesthesiology

Greenblatt DJ.
PMID: 911048
Anesthesiology. 1977 Nov;47(5):405-6. doi: 10.1097/00000542-197711000-00001.
Free Article

No abstract available.

Magnetic resonance as a non-invasive tool to study metabolism in pharmacological research.

Trends in pharmacological sciences

Kaplan O, Cohen JS.
PMID: 2256178
Trends Pharmacol Sci. 1990 Oct;11(10):398-400. doi: 10.1016/0165-6147(90)90143-v.

No abstract available.

Showing 37 to 48 of 79 entries