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Evaluating exposure using confidence intervals: implication in tiered quantitation of metabolites for safety risks.

Bioanalysis

Niwa M, Ishii T, Ono K, Kuriyama S, Nakai N, Hosaka S, Mayumi T, Yasuda Y, Yamakawa T.
PMID: 30295549
Bioanalysis. 2018 Oct;10(19):1553-1556. doi: 10.4155/bio-2018-0217.

No abstract available.

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Niwa M, Ishii T, Ono K, et al. Evaluating exposure using confidence intervals: implication in tiered quantitation of metabolites for safety risks. Bioanalysis. 2018;10(19):1553-1556doi: 10.4155/bio-2018-0217.
Niwa, M., Ishii, T., Ono, K., Kuriyama, S., Nakai, N., Hosaka, S., Mayumi, T., Yasuda, Y., & Yamakawa, T. (2018). Evaluating exposure using confidence intervals: implication in tiered quantitation of metabolites for safety risks. Bioanalysis, 10(19), 1553-1556. https://doi.org/10.4155/bio-2018-0217
Niwa, Makoto, et al. "Evaluating exposure using confidence intervals: implication in tiered quantitation of metabolites for safety risks." Bioanalysis vol. 10,19 (2018): 1553-1556. doi: https://doi.org/10.4155/bio-2018-0217
Niwa M, Ishii T, Ono K, Kuriyama S, Nakai N, Hosaka S, Mayumi T, Yasuda Y, Yamakawa T. Evaluating exposure using confidence intervals: implication in tiered quantitation of metabolites for safety risks. Bioanalysis. 2018 Oct;10(19):1553-1556. doi: 10.4155/bio-2018-0217. PMID: 30295549.
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The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation.

Advanced drug delivery reviews

Siccardi M, Rannard S, Owen A.
PMID: 29959958
Adv Drug Deliv Rev. 2018 Jun;131:116-121. doi: 10.1016/j.addr.2018.06.016. Epub 2018 Jun 27.

The use of solid drug nanoparticles (SDN) has become an established approach to improve drug delivery, supporting enhancement of oral absorption and long-acting administration strategies. A broad range of SDNs have been successfully utilised for multiple products and several...

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Siccardi M, Rannard S, Owen A. The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation. Adv Drug Deliv Rev. 2018;131:116-121doi: 10.1016/j.addr.2018.06.016.
Siccardi, M., Rannard, S., & Owen, A. (2018). The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation. Advanced drug delivery reviews, 131116-121. https://doi.org/10.1016/j.addr.2018.06.016
Siccardi, Marco, et al. "The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation." Advanced drug delivery reviews vol. 131 (2018): 116-121. doi: https://doi.org/10.1016/j.addr.2018.06.016
Siccardi M, Rannard S, Owen A. The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation. Adv Drug Deliv Rev. 2018 Jun;131:116-121. doi: 10.1016/j.addr.2018.06.016. Epub 2018 Jun 27. PMID: 29959958.
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The clinical relevance of pharmacokinetics.

The Journal of antimicrobial chemotherapy

Wright N.
PMID: 7107543
J Antimicrob Chemother. 1982 Jul;10(1):2-4. doi: 10.1093/jac/10.1.2.

No abstract available.

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Wright N. The clinical relevance of pharmacokinetics. J Antimicrob Chemother. 1982;10(1):2-4doi: 10.1093/jac/10.1.2.
Wright, N. (1982). The clinical relevance of pharmacokinetics. The Journal of antimicrobial chemotherapy, 10(1), 2-4. https://doi.org/10.1093/jac/10.1.2
Wright, N. "The clinical relevance of pharmacokinetics." The Journal of antimicrobial chemotherapy vol. 10,1 (1982): 2-4. doi: https://doi.org/10.1093/jac/10.1.2
Wright N. The clinical relevance of pharmacokinetics. J Antimicrob Chemother. 1982 Jul;10(1):2-4. doi: 10.1093/jac/10.1.2. PMID: 7107543.
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Metabolism, pharmacokinetics, and toxicokinetics defined.

Drug metabolism reviews

Di Carlo FJ.
PMID: 7084027
Drug Metab Rev. 1982;13(1):1-4. doi: 10.3109/03602538209002228.

No abstract available.

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Di Carlo FJ. Metabolism, pharmacokinetics, and toxicokinetics defined. Drug Metab Rev. 1982;13(1):1-4doi: 10.3109/03602538209002228.
Di Carlo, F. J. (1982). Metabolism, pharmacokinetics, and toxicokinetics defined. Drug metabolism reviews, 13(1), 1-4. https://doi.org/10.3109/03602538209002228
Di Carlo, F J. "Metabolism, pharmacokinetics, and toxicokinetics defined." Drug metabolism reviews vol. 13,1 (1982): 1-4. doi: https://doi.org/10.3109/03602538209002228
Di Carlo FJ. Metabolism, pharmacokinetics, and toxicokinetics defined. Drug Metab Rev. 1982;13(1):1-4. doi: 10.3109/03602538209002228. PMID: 7084027.
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Basic concepts in drug metabolism: Part II.

Journal of clinical pharmacology

Jordan RA, Woolf TF.
PMID: 3316305
J Clin Pharmacol. 1987 Feb;27(2):87-90. doi: 10.1002/j.1552-4604.1987.tb02166.x.

There are numerous articles available that provide a comprehensive review of basic concepts of drug metabolism. Our intent in this review article was to provide an overview of some of the basic pathways for drug metabolism, how they may...

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Jordan RA, Woolf TF. Basic concepts in drug metabolism: Part II. J Clin Pharmacol. 1987;27(2):87-90doi: 10.1002/j.1552-4604.1987.tb02166.x.
Jordan, R. A., & Woolf, T. F. (1987). Basic concepts in drug metabolism: Part II. Journal of clinical pharmacology, 27(2), 87-90. https://doi.org/10.1002/j.1552-4604.1987.tb02166.x
Jordan, R A, and Woolf, T F. "Basic concepts in drug metabolism: Part II." Journal of clinical pharmacology vol. 27,2 (1987): 87-90. doi: https://doi.org/10.1002/j.1552-4604.1987.tb02166.x
Jordan RA, Woolf TF. Basic concepts in drug metabolism: Part II. J Clin Pharmacol. 1987 Feb;27(2):87-90. doi: 10.1002/j.1552-4604.1987.tb02166.x. PMID: 3316305.
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Oral sustained-release products: pro's and con's.

Drug and therapeutics bulletin

[No authors listed]
PMID: 6468281
Drug Ther Bull. 1984 Jul 30;22(15):57-60.

No abstract available.

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Oral sustained-release products: pro's and con's. Drug Ther Bull. 1984;22(15):57-60
(1984). Oral sustained-release products: pro's and con's. Drug and therapeutics bulletin, 22(15), 57-60.
"Oral sustained-release products: pro's and con's." Drug and therapeutics bulletin vol. 22,15 (1984): 57-60.
Oral sustained-release products: pro's and con's. Drug Ther Bull. 1984 Jul 30;22(15):57-60. PMID: 6468281.
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Estimation of mean residence time from data obtained when multiple-dosing steady state has been reached.

Journal of pharmaceutical sciences

Pfeffer M.
PMID: 6737281
J Pharm Sci. 1984 Jun;73(6):854-6. doi: 10.1002/jps.2600730645.

No abstract available.

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Pfeffer M. Estimation of mean residence time from data obtained when multiple-dosing steady state has been reached. J Pharm Sci. 1984;73(6):854-6doi: 10.1002/jps.2600730645.
Pfeffer, M. (1984). Estimation of mean residence time from data obtained when multiple-dosing steady state has been reached. Journal of pharmaceutical sciences, 73(6), 854-6. https://doi.org/10.1002/jps.2600730645
Pfeffer, M. "Estimation of mean residence time from data obtained when multiple-dosing steady state has been reached." Journal of pharmaceutical sciences vol. 73,6 (1984): 854-6. doi: https://doi.org/10.1002/jps.2600730645
Pfeffer M. Estimation of mean residence time from data obtained when multiple-dosing steady state has been reached. J Pharm Sci. 1984 Jun;73(6):854-6. doi: 10.1002/jps.2600730645. PMID: 6737281.
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Practical solution to the Michaelis-Menten equation.

Journal of pharmaceutical sciences

Veng-Pedersen P, Suaréz L.
PMID: 6663492
J Pharm Sci. 1983 Dec;72(12):1483-5. doi: 10.1002/jps.2600721232.

No abstract available.

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Veng-Pedersen P, Suaréz L. Practical solution to the Michaelis-Menten equation. J Pharm Sci. 1983;72(12):1483-5doi: 10.1002/jps.2600721232.
Veng-Pedersen, P., & Suaréz, L. (1983). Practical solution to the Michaelis-Menten equation. Journal of pharmaceutical sciences, 72(12), 1483-5. https://doi.org/10.1002/jps.2600721232
Veng-Pedersen, P, and Suaréz, L. "Practical solution to the Michaelis-Menten equation." Journal of pharmaceutical sciences vol. 72,12 (1983): 1483-5. doi: https://doi.org/10.1002/jps.2600721232
Veng-Pedersen P, Suaréz L. Practical solution to the Michaelis-Menten equation. J Pharm Sci. 1983 Dec;72(12):1483-5. doi: 10.1002/jps.2600721232. PMID: 6663492.
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PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures.

BMC bioinformatics

Emon MA, Domingo-Fernández D, Hoyt CT, Hofmann-Apitius M.
PMID: 32503412
BMC Bioinformatics. 2020 Jun 05;21(1):231. doi: 10.1186/s12859-020-03568-5.

BACKGROUND: During the last decade, there has been a surge towards computational drug repositioning owing to constantly increasing -omics data in the biomedical research field. While numerous existing methods focus on the integration of heterogeneous data to propose candidate...

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Emon MA, Domingo-Fernández D, Hoyt CT, et al. PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures. BMC Bioinformatics. 2020;21(1):231doi: 10.1186/s12859-020-03568-5.
Emon, M. A., Domingo-Fernández, D., Hoyt, C. T., & Hofmann-Apitius, M. (2020). PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures. BMC bioinformatics, 21(1), 231. https://doi.org/10.1186/s12859-020-03568-5
Emon, Mohammad Asif, et al. "PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures." BMC bioinformatics vol. 21,1 (2020): 231. doi: https://doi.org/10.1186/s12859-020-03568-5
Emon MA, Domingo-Fernández D, Hoyt CT, Hofmann-Apitius M. PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures. BMC Bioinformatics. 2020 Jun 05;21(1):231. doi: 10.1186/s12859-020-03568-5. PMID: 32503412; PMCID: PMC7275349.
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Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome.

Endocrinology and metabolism (Seoul, Korea)

Son JW, Shoaie S, Lee S.
PMID: 32981293
Endocrinol Metab (Seoul). 2020 Sep;35(3):507-514. doi: 10.3803/EnM.2020.303. Epub 2020 Sep 22.

The complex and dynamic nature of human physiology, as exemplified by metabolism, has often been overlooked due to the lack of quantitative and systems approaches. Recently, systems biology approaches have pushed the boundaries of our current understanding of complex...

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Son JW, Shoaie S, Lee S. Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome. Endocrinol Metab (Seoul). 2020;35(3):507-514doi: 10.3803/EnM.2020.303.
Son, J. W., Shoaie, S., & Lee, S. (2020). Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome. Endocrinology and metabolism (Seoul, Korea), 35(3), 507-514. https://doi.org/10.3803/EnM.2020.303
Son, Jang Won, et al. "Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome." Endocrinology and metabolism (Seoul, Korea) vol. 35,3 (2020): 507-514. doi: https://doi.org/10.3803/EnM.2020.303
Son JW, Shoaie S, Lee S. Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome. Endocrinol Metab (Seoul). 2020 Sep;35(3):507-514. doi: 10.3803/EnM.2020.303. Epub 2020 Sep 22. PMID: 32981293; PMCID: PMC7520591.
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Regulatory approaches to the bioaccumulation of drugs: a polar bare walks into a bar….

Integrated environmental assessment and management

Kullik SA, Rattray AG.
PMID: 25234495
Integr Environ Assess Manag. 2014 Oct;10(4):600-1. doi: 10.1002/ieam.1566.

No abstract available.

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Kullik SA, Rattray AG. Regulatory approaches to the bioaccumulation of drugs: a polar bare walks into a bar…. Integr Environ Assess Manag. 2014;10(4):600-1doi: 10.1002/ieam.1566.
Kullik, S. A., & Rattray, A. G. (2014). Regulatory approaches to the bioaccumulation of drugs: a polar bare walks into a bar…. Integrated environmental assessment and management, 10(4), 600-1. https://doi.org/10.1002/ieam.1566
Kullik, Sigrun A, and Rattray, A Graham M. "Regulatory approaches to the bioaccumulation of drugs: a polar bare walks into a bar…." Integrated environmental assessment and management vol. 10,4 (2014): 600-1. doi: https://doi.org/10.1002/ieam.1566
Kullik SA, Rattray AG. Regulatory approaches to the bioaccumulation of drugs: a polar bare walks into a bar…. Integr Environ Assess Manag. 2014 Oct;10(4):600-1. doi: 10.1002/ieam.1566. PMID: 25234495.
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The human microbiome and therapeutics.

American journal of therapeutics

Somberg JC.
PMID: 22772032
Am J Ther. 2012 Jul;19(4):247. doi: 10.1097/MJT.0b013e318265ed0f.

No abstract available.

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Somberg JC. The human microbiome and therapeutics. Am J Ther. 2012;19(4):247doi: 10.1097/MJT.0b013e318265ed0f.
Somberg, J. C. (2012). The human microbiome and therapeutics. American journal of therapeutics, 19(4), 247. https://doi.org/10.1097/MJT.0b013e318265ed0f
Somberg, John C. "The human microbiome and therapeutics." American journal of therapeutics vol. 19,4 (2012): 247. doi: https://doi.org/10.1097/MJT.0b013e318265ed0f
Somberg JC. The human microbiome and therapeutics. Am J Ther. 2012 Jul;19(4):247. doi: 10.1097/MJT.0b013e318265ed0f. PMID: 22772032.
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Showing 13 to 24 of 79 entries