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The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation.

Advanced drug delivery reviews

Siccardi M, Rannard S, Owen A.
PMID: 29959958
Adv Drug Deliv Rev. 2018 Jun;131:116-121. doi: 10.1016/j.addr.2018.06.016. Epub 2018 Jun 27.

The use of solid drug nanoparticles (SDN) has become an established approach to improve drug delivery, supporting enhancement of oral absorption and long-acting administration strategies. A broad range of SDNs have been successfully utilised for multiple products and several...

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Siccardi M, Rannard S, Owen A. The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation. Adv Drug Deliv Rev. 2018;131:116-121doi: 10.1016/j.addr.2018.06.016.
Siccardi, M., Rannard, S., & Owen, A. (2018). The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation. Advanced drug delivery reviews, 131116-121. https://doi.org/10.1016/j.addr.2018.06.016
Siccardi, Marco, et al. "The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation." Advanced drug delivery reviews vol. 131 (2018): 116-121. doi: https://doi.org/10.1016/j.addr.2018.06.016
Siccardi M, Rannard S, Owen A. The emerging role of physiologically based pharmacokinetic modelling in solid drug nanoparticle translation. Adv Drug Deliv Rev. 2018 Jun;131:116-121. doi: 10.1016/j.addr.2018.06.016. Epub 2018 Jun 27. PMID: 29959958.
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Crystals and Crystallization in Drug Delivery Design.

Molecular pharmaceutics

Taylor LS, Braun DE, Steed JW.
PMID: 33594892
Mol Pharm. 2021 Mar 01;18(3):751-753. doi: 10.1021/acs.molpharmaceut.0c01157. Epub 2021 Feb 17.

No abstract available.

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Taylor LS, Braun DE, Steed JW. Crystals and Crystallization in Drug Delivery Design. Mol Pharm. 2021;18(3):751-753doi: 10.1021/acs.molpharmaceut.0c01157.
Taylor, L. S., Braun, D. E., & Steed, J. W. (2021). Crystals and Crystallization in Drug Delivery Design. Molecular pharmaceutics, 18(3), 751-753. https://doi.org/10.1021/acs.molpharmaceut.0c01157
Taylor, Lynne S, et al. "Crystals and Crystallization in Drug Delivery Design." Molecular pharmaceutics vol. 18,3 (2021): 751-753. doi: https://doi.org/10.1021/acs.molpharmaceut.0c01157
Taylor LS, Braun DE, Steed JW. Crystals and Crystallization in Drug Delivery Design. Mol Pharm. 2021 Mar 01;18(3):751-753. doi: 10.1021/acs.molpharmaceut.0c01157. Epub 2021 Feb 17. PMID: 33594892.
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New Computational Approaches Aimed at the Prediction of More Selective and Active Drugs.

Current topics in medicinal chemistry

Concu R.
PMID: 32862825
Curr Top Med Chem. 2020;20(18):1581. doi: 10.2174/156802662018200630150100.

No abstract available.

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Concu R. New Computational Approaches Aimed at the Prediction of More Selective and Active Drugs. Curr Top Med Chem. 2020;20(18):1581doi: 10.2174/156802662018200630150100.
Concu, R. (2020). New Computational Approaches Aimed at the Prediction of More Selective and Active Drugs. Current topics in medicinal chemistry, 20(18), 1581. https://doi.org/10.2174/156802662018200630150100
Concu, Riccardo. "New Computational Approaches Aimed at the Prediction of More Selective and Active Drugs." Current topics in medicinal chemistry vol. 20,18 (2020): 1581. doi: https://doi.org/10.2174/156802662018200630150100
Concu R. New Computational Approaches Aimed at the Prediction of More Selective and Active Drugs. Curr Top Med Chem. 2020;20(18):1581. doi: 10.2174/156802662018200630150100. PMID: 32862825.
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Recent In Silico Resources for Drug Design and Discovery.

Current medicinal chemistry

Veljkovic N.
PMID: 31584358
Curr Med Chem. 2019;26(21):3836-3837. doi: 10.2174/092986732621190919104301.

No abstract available.

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Veljkovic N. Recent In Silico Resources for Drug Design and Discovery. Curr Med Chem. 2019;26(21):3836-3837doi: 10.2174/092986732621190919104301.
Veljkovic, N. (2019). Recent In Silico Resources for Drug Design and Discovery. Current medicinal chemistry, 26(21), 3836-3837. https://doi.org/10.2174/092986732621190919104301
Veljkovic, Nevena. "Recent In Silico Resources for Drug Design and Discovery." Current medicinal chemistry vol. 26,21 (2019): 3836-3837. doi: https://doi.org/10.2174/092986732621190919104301
Veljkovic N. Recent In Silico Resources for Drug Design and Discovery. Curr Med Chem. 2019;26(21):3836-3837. doi: 10.2174/092986732621190919104301. PMID: 31584358.
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Model Informed Drug Development: Collaboration Through A Common Framework.

Clinical pharmacology and therapeutics

Anziano RJ, Milligan PA.
PMID: 33111309
Clin Pharmacol Ther. 2021 Nov;110(5):1165-1167. doi: 10.1002/cpt.2066. Epub 2020 Oct 28.

No abstract available.

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Anziano RJ, Milligan PA. Model Informed Drug Development: Collaboration Through A Common Framework. Clin Pharmacol Ther. 2020;110(5):1165-1167doi: 10.1002/cpt.2066.
Anziano, R. J., & Milligan, P. A. (2021). Model Informed Drug Development: Collaboration Through A Common Framework. Clinical pharmacology and therapeutics, 110(5), 1165-1167. https://doi.org/10.1002/cpt.2066
Anziano, Richard J, and Milligan, Peter A. "Model Informed Drug Development: Collaboration Through A Common Framework." Clinical pharmacology and therapeutics vol. 110,5 (2021): 1165-1167. doi: https://doi.org/10.1002/cpt.2066
Anziano RJ, Milligan PA. Model Informed Drug Development: Collaboration Through A Common Framework. Clin Pharmacol Ther. 2021 Nov;110(5):1165-1167. doi: 10.1002/cpt.2066. Epub 2020 Oct 28. PMID: 33111309; PMCID: PMC8596610.
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Targeting Strategies for Tissue-Specific Drug Delivery.

Cell

Zhao Z, Ukidve A, Kim J, Mitragotri S.
PMID: 32243788
Cell. 2020 Apr 02;181(1):151-167. doi: 10.1016/j.cell.2020.02.001.

Off-target effects of systemically administered drugs have been a major hurdle in designing therapies with desired efficacy and acceptable toxicity. Developing targeting strategies to enable site-specific drug delivery holds promise in reducing off-target effects, decreasing unwanted toxicities, and thereby...

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Zhao Z, Ukidve A, Kim J, et al. Targeting Strategies for Tissue-Specific Drug Delivery. Cell. 2020;181(1):151-167doi: 10.1016/j.cell.2020.02.001.
Zhao, Z., Ukidve, A., Kim, J., & Mitragotri, S. (2020). Targeting Strategies for Tissue-Specific Drug Delivery. Cell, 181(1), 151-167. https://doi.org/10.1016/j.cell.2020.02.001
Zhao, Zongmin, et al. "Targeting Strategies for Tissue-Specific Drug Delivery." Cell vol. 181,1 (2020): 151-167. doi: https://doi.org/10.1016/j.cell.2020.02.001
Zhao Z, Ukidve A, Kim J, Mitragotri S. Targeting Strategies for Tissue-Specific Drug Delivery. Cell. 2020 Apr 02;181(1):151-167. doi: 10.1016/j.cell.2020.02.001. PMID: 32243788.
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How physiologically based pharmacokinetic models should be improved for drug development.

Future medicinal chemistry

Hempel G.
PMID: 32349520
Future Med Chem. 2020 Jun;12(12):1107-1109. doi: 10.4155/fmc-2020-0074. Epub 2020 Apr 30.

No abstract available.

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Hempel G. How physiologically based pharmacokinetic models should be improved for drug development. Future Med Chem. 2020;12(12):1107-1109doi: 10.4155/fmc-2020-0074.
Hempel, G. (2020). How physiologically based pharmacokinetic models should be improved for drug development. Future medicinal chemistry, 12(12), 1107-1109. https://doi.org/10.4155/fmc-2020-0074
Hempel, Georg. "How physiologically based pharmacokinetic models should be improved for drug development." Future medicinal chemistry vol. 12,12 (2020): 1107-1109. doi: https://doi.org/10.4155/fmc-2020-0074
Hempel G. How physiologically based pharmacokinetic models should be improved for drug development. Future Med Chem. 2020 Jun;12(12):1107-1109. doi: 10.4155/fmc-2020-0074. Epub 2020 Apr 30. PMID: 32349520.
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Microfluidics in Nanomedicine.

Pharmaceutical nanotechnology

Boyd BJ, McDowell A.
PMID: 31840609
Pharm Nanotechnol. 2019;7(6):422. doi: 10.2174/221173850706191210152137.

No abstract available.

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Boyd BJ, McDowell A. Microfluidics in Nanomedicine. Pharm Nanotechnol. 2019;7(6):422doi: 10.2174/221173850706191210152137.
Boyd, B. J., & McDowell, A. (2019). Microfluidics in Nanomedicine. Pharmaceutical nanotechnology, 7(6), 422. https://doi.org/10.2174/221173850706191210152137
Boyd, Ben J, and McDowell, Arlene. "Microfluidics in Nanomedicine." Pharmaceutical nanotechnology vol. 7,6 (2019): 422. doi: https://doi.org/10.2174/221173850706191210152137
Boyd BJ, McDowell A. Microfluidics in Nanomedicine. Pharm Nanotechnol. 2019;7(6):422. doi: 10.2174/221173850706191210152137. PMID: 31840609.
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Current Advances in Computational and Experimental Approaches for Nanoparticle-Drug Conjugates.

Current topics in medicinal chemistry

Lin X.
PMID: 33443002
Curr Top Med Chem. 2021;21(2):90-91. doi: 10.2174/156802662102201211114037.

No abstract available.

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Lin X. Current Advances in Computational and Experimental Approaches for Nanoparticle-Drug Conjugates. Curr Top Med Chem. 2021;21(2):90-91doi: 10.2174/156802662102201211114037.
Lin, X. (2021). Current Advances in Computational and Experimental Approaches for Nanoparticle-Drug Conjugates. Current topics in medicinal chemistry, 21(2), 90-91. https://doi.org/10.2174/156802662102201211114037
Lin, Xubo. "Current Advances in Computational and Experimental Approaches for Nanoparticle-Drug Conjugates." Current topics in medicinal chemistry vol. 21,2 (2021): 90-91. doi: https://doi.org/10.2174/156802662102201211114037
Lin X. Current Advances in Computational and Experimental Approaches for Nanoparticle-Drug Conjugates. Curr Top Med Chem. 2021;21(2):90-91. doi: 10.2174/156802662102201211114037. PMID: 33443002.
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New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by .

Journal of medicinal chemistry

Müller CE, Hansen FK, Gütschow M, Lindsley CW, Liotta D.
PMID: 34591485
J Med Chem. 2021 Oct 14;64(19):13935-13936. doi: 10.1021/acs.jmedchem.1c01548. Epub 2021 Sep 30.

No abstract available.

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Müller CE, Hansen FK, Gütschow M, et al. New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by . J Med Chem. 2021;64(19):13935-13936doi: 10.1021/acs.jmedchem.1c01548.
Müller, C. E., Hansen, F. K., Gütschow, M., Lindsley, C. W., & Liotta, D. (2021). New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by . Journal of medicinal chemistry, 64(19), 13935-13936. https://doi.org/10.1021/acs.jmedchem.1c01548
Müller, Christa E, et al. "New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by ." Journal of medicinal chemistry vol. 64,19 (2021): 13935-13936. doi: https://doi.org/10.1021/acs.jmedchem.1c01548
Müller CE, Hansen FK, Gütschow M, Lindsley CW, Liotta D. New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by . J Med Chem. 2021 Oct 14;64(19):13935-13936. doi: 10.1021/acs.jmedchem.1c01548. Epub 2021 Sep 30. PMID: 34591485.
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Back to the Medicinal Chemistry Future.

Journal of medicinal chemistry

Giustiniano M, Gruber CW, Kent CN, Trippier PC.
PMID: 34719927
J Med Chem. 2021 Nov 11;64(21):15515-15518. doi: 10.1021/acs.jmedchem.1c01788. Epub 2021 Nov 01.

No abstract available.

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Giustiniano M, Gruber CW, Kent CN, et al. Back to the Medicinal Chemistry Future. J Med Chem. 2021;64(21):15515-15518doi: 10.1021/acs.jmedchem.1c01788.
Giustiniano, M., Gruber, C. W., Kent, C. N., & Trippier, P. C. (2021). Back to the Medicinal Chemistry Future. Journal of medicinal chemistry, 64(21), 15515-15518. https://doi.org/10.1021/acs.jmedchem.1c01788
Giustiniano, Mariateresa, et al. "Back to the Medicinal Chemistry Future." Journal of medicinal chemistry vol. 64,21 (2021): 15515-15518. doi: https://doi.org/10.1021/acs.jmedchem.1c01788
Giustiniano M, Gruber CW, Kent CN, Trippier PC. Back to the Medicinal Chemistry Future. J Med Chem. 2021 Nov 11;64(21):15515-15518. doi: 10.1021/acs.jmedchem.1c01788. Epub 2021 Nov 01. PMID: 34719927.
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WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets.

BMC bioinformatics

Durrant JD, Amaro RE.
PMID: 24886360
BMC Bioinformatics. 2014 May 23;15:159. doi: 10.1186/1471-2105-15-159.

BACKGROUND: Sharing sets of chemical data (e.g., chemical properties, docking scores, etc.) among collaborators with diverse skill sets is a common task in computer-aided drug design and medicinal chemistry. The ability to associate this data with images of the...

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Durrant JD, Amaro RE. WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets. BMC Bioinformatics. 2014;15:159doi: 10.1186/1471-2105-15-159.
Durrant, J. D., & Amaro, R. E. (2014). WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets. BMC bioinformatics, 15159. https://doi.org/10.1186/1471-2105-15-159
Durrant, Jacob D, and Amaro, Rommie E. "WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets." BMC bioinformatics vol. 15 (2014): 159. doi: https://doi.org/10.1186/1471-2105-15-159
Durrant JD, Amaro RE. WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets. BMC Bioinformatics. 2014 May 23;15:159. doi: 10.1186/1471-2105-15-159. PMID: 24886360; PMCID: PMC4094277.
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Showing 25 to 36 of 80 entries