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Showing 169 to 176 of 176 entries
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Precision medicine in oncology: what is it exactly and where are we?.

Personalized medicine

Le Tourneau C, Kamal M, Bièche I.
PMID: 30260312
Per Med. 2018 Sep;15(5):351-353. doi: 10.2217/pme-2018-0036. Epub 2018 Sep 27.

No abstract available.

Key Lessons Learned from Moffitt's Molecular Tumor Board: The Clinical Genomics Action Committee Experience.

The oncologist

Knepper TC, Bell GC, Hicks JK, Padron E, Teer JK, Vo TT, Gillis NK, Mason NT, McLeod HL, Walko CM.
PMID: 28179575
Oncologist. 2017 Feb;22(2):144-151. doi: 10.1634/theoncologist.2016-0195. Epub 2017 Feb 08.

BACKGROUND: The increasing practicality of genomic sequencing technology has led to its incorporation into routine clinical practice. Successful identification and targeting of driver genomic alterations that provide proliferative and survival advantages to tumor cells have led to approval and...

[Current status and future prospect of internal medicine treatment for advanced esophageal cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology]

Wang F, Fan QX.
PMID: 27647396
Zhonghua Zhong Liu Za Zhi. 2016 Sep 23;38(9):655-9. doi: 10.3760/cma.j.issn.0253-3766.2016.09.004.

Esophageal cancer (EC) is one of common malignant tumors, and the incidence and mortality of EC in China rank the first place in the world. Because of the occult onset, the early atypical symptoms, and the lack of effective...

Targeted Therapy and Immunotherapy for Melanoma in Japan.

Current treatment options in oncology

Namikawa K, Yamazaki N.
PMID: 30675668
Curr Treat Options Oncol. 2019 Jan 24;20(1):7. doi: 10.1007/s11864-019-0607-8.

OPINION STATEMENT: Melanoma has several clinically and pathologically distinguishable subtypes, which also differ genetically. Mutation patterns vary among different melanoma subtypes, and efficacy of immune-checkpoint inhibitors differs depending on the subtype of melanoma. In spite of the recent revolution...

Clonotyping for precision oncology.

Drug discovery today

Dang HX, Maher CA.
PMID: 26494143
Drug Discov Today. 2015 Dec;20(12):1464-9. doi: 10.1016/j.drudis.2015.10.010. Epub 2015 Oct 19.

Advances in identifying subpopulations of cancer cells and reconstructing the clonal evolution of tumors greatly enhance our understanding of the molecular events within a patient and their context relative to one another. In the rapidly unfolding era of personalized...

Releasing the brakes to fight cancer: The recent discovery of checkpoints has boosted the field of cancer immunotherapy.

EMBO reports

Weigmann K.
PMID: 27458238
EMBO Rep. 2016 Sep;17(9):1257-60. doi: 10.15252/embr.201643038. Epub 2016 Jul 25.

No abstract available.

Progress in systemic therapy for triple-negative breast cancer.

Frontiers of medicine

Mo H, Xu B.
PMID: 32789731
Front Med. 2021 Feb;15(1):1-10. doi: 10.1007/s11684-020-0741-5. Epub 2020 Aug 13.

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with a heterogeneous genetic profile. Chemotherapy exhibits substantial activity in a small subset of these patients. Drug resistance is inevitable. Major progress has been made in the...

A Trial of Targeted Therapy.

International journal of radiation oncology, biology, physics

Thariat J.
PMID: 34273321
Int J Radiat Oncol Biol Phys. 2021 Aug 01;110(5):1265-1266. doi: 10.1016/j.ijrobp.2021.04.034.

No abstract available.

Showing 169 to 176 of 176 entries