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Showing 2629 to 2640 of 2658 entries
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Immunotherapies targeting stimulatory pathways and beyond.

Journal of hematology & oncology

Marin-Acevedo JA, Kimbrough EO, Manochakian R, Zhao Y, Lou Y.
PMID: 33980266
J Hematol Oncol. 2021 May 12;14(1):78. doi: 10.1186/s13045-021-01085-3.

Co-stimulatory and co-inhibitory molecules play a critical role in T cell function. Tumor cells escape immune surveillance by promoting immunosuppression. Immunotherapy targeting inhibitory molecules like anti-CTLA-4 and anti-PD-1/PD-L1 were developed to overcome these immunosuppressive effects. These agents have demonstrated...

Allergy, Inflammatory, and Autoimmune Emergencies.

Emergency medicine clinics of North America

Mattu A.
PMID: 34782095
Emerg Med Clin North Am. 2022 Feb;40(1):xiii-xiv. doi: 10.1016/j.emc.2021.10.002.

No abstract available.

The Interactive Effects of Cognition on Coping Styles among Chinese during the COVID-19 Pandemic.

International journal of environmental research and public health

Cai Z, Zheng S, Huang Y, Au WW, Qiu Z, Wu K.
PMID: 33803737
Int J Environ Res Public Health. 2021 Mar 18;18(6). doi: 10.3390/ijerph18063148.

BACKGROUND: The outbreak of Coronavirus Disease 2019 (COVID-19) has seriously affected people's life. The main aim of our investigation was to determine the interactive effects of disease awareness on coping style among Chinese residents during the COVID-19 pandemic.METHODS: A...

Tombstone Sign in an Inferior Wall Myocardial Infarction.

The American journal of cardiology

Kawji MM, Glancy DL.
PMID: 34538403
Am J Cardiol. 2021 Nov 15;159:140-141. doi: 10.1016/j.amjcard.2021.08.006. Epub 2021 Sep 15.

A 62-year-old white patient presents with markedly ischemic electrocardiogram, notable for Tombstone sign.

Perceptions of COVID-19-related risk and mortality among ethnically diverse healthcare professionals in the UK.

Ethnicity & health

Ali P, Adam Z, West J, Pareek M, Raza M, Iqbal J.
PMID: 33334170
Ethn Health. 2021 Jan;26(1):1-10. doi: 10.1080/13557858.2020.1849568. Epub 2020 Dec 17.

BACKGROUND: A number of Healthcare Practitioners (HCPs), mostly from Black, Asian and minority ethnic (BAME) origin have died with COVID-19. This survey aimed to explore the views of an ethnically diverse sample of HCPs in the UK about COVID-19-related...

The impact of the COVID-19 pandemic on mental health and well-being of people living with a long-term physical health condition: a qualitative study.

BMC public health

Fisher A, Roberts A, McKinlay AR, Fancourt D, Burton A.
PMID: 34620136
BMC Public Health. 2021 Oct 07;21(1):1801. doi: 10.1186/s12889-021-11751-3.

BACKGROUND: The COVID-19 pandemic and associated restrictions caused major global disruption. Individuals with long-term physical health conditions (LTCs) are at higher risk of severe illness and often subject to the strictest pandemic guidance, so may be disproportionally affected. The...

Predictive factors of in-hospital mortality in patients with laboratory-confirmed Escherichia coli, Klebsiella species or Pseudomonas aeruginosa bloodstream infections.

PloS one

Mitchell E, Pearce M, Roberts A, Newton J.
PMID: 34727130
PLoS One. 2021 Nov 02;16(11):e0259305. doi: 10.1371/journal.pone.0259305. eCollection 2021.

Gram-negative bloodstream infections (GNBSI) are confirmed by the presence of gram-negative bacteria in the bloodstream and pose a significant healthcare issue as they increase the risk of sepsis and mortality. In England, the aim is to reduce GNBSI cases...

A Case of Coronvirus Disease 2019 with Psychological Disorders.

Psychiatria Danubina

Chen J, Tian C, Cheng X, Huang Y, Tang L, Wang R, Zeng X.
PMID: 33370770
Psychiatr Danub. 2020;32(3):581-583. doi: 10.24869/psyd.2020.581.

No abstract available.

Population Segmentation Based on Healthcare Needs: Validation of a Brief Clinician-Administered Tool.

Journal of general internal medicine

Chong JL, Matchar DB, Tan Y, Sri Kumaran S, Gandhi M, Ong MEH, Wong KS.
PMID: 32607929
J Gen Intern Med. 2021 Jan;36(1):9-16. doi: 10.1007/s11606-020-05962-4. Epub 2020 Jun 30.

BACKGROUND: As populations age with increasingly complex chronic conditions, segmenting populations into clinically meaningful categories of healthcare and related service needs can provide healthcare planners with crucial information to optimally meet needs. However, while conventional approaches typically involve electronic...

Racial/Ethnic differences in the health-related quality of life of cancer patients.

Journal of pain and symptom management

Rao D, Debb S, Blitz D, Choi SW, Cella D.
PMID: 18504096
J Pain Symptom Manage. 2008 Nov;36(5):488-96. doi: 10.1016/j.jpainsymman.2007.11.012. Epub 2008 May 27.

Previous research has suggested that, when compared to European Americans (EAs), African Americans (AAs) are at higher risk of metastatic disease at time of cancer diagnosis, and a higher risk of shorter survival. Although AA patients have reported worse...

Risk Stratification for Early Detection of Diabetes and Hypertension in Resource-Limited Settings: Machine Learning Analysis.

Journal of medical Internet research

Boutilier JJ, Chan TCY, Ranjan M, Deo S.
PMID: 33475518
J Med Internet Res. 2021 Jan 21;23(1):e20123. doi: 10.2196/20123.

BACKGROUND: The impending scale up of noncommunicable disease screening programs in low- and middle-income countries coupled with limited health resources require that such programs be as accurate as possible at identifying patients at high risk.OBJECTIVE: The aim of this...

Social factors and pain worsening: a retrospective cohort study.

British journal of anaesthesia

Prego-Domínguez J, Skillgate E, Orsini N, Takkouche B.
PMID: 34119308
Br J Anaesth. 2021 Aug;127(2):289-295. doi: 10.1016/j.bja.2021.04.021. Epub 2021 Jun 10.

BACKGROUND: Pain, specifically chronic pain, is a major public health issue worldwide with considerable health-related consequences and large economic impact. The relation between socioeconomic status and pain occurrence is well established. However, little is known on the relation between...

Showing 2629 to 2640 of 2658 entries