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Showing 13 to 24 of 203 entries
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Digital microfluidic operations on micro-electrode dot array architecture.

IET nanobiotechnology

Wang G, Teng D, Fan SK.
PMID: 22149873
IET Nanobiotechnol. 2011 Dec;5(4):152-60. doi: 10.1049/iet-nbt.2011.0018.

As digital microfluidics-based biochips find more applications, their complexity is expected to increase significantly owing to the trend of multiple and concurrent assays on the chip. There is a pressing need to deliver a top-down design methodology that the...

Fusion and sorting of two parallel trains of droplets using a railroad-like channel network and guiding tracks.

Lab on a chip

Xu L, Lee H, Panchapakesan R, Oh KW.
PMID: 22814673
Lab Chip. 2012 Oct 21;12(20):3936-42. doi: 10.1039/c2lc40456g.

We propose a robust droplet fusion and sorting method for two parallel trains of droplets that is relatively insensitive to frequency and phase mismatch. Conventional methods of droplet fusion require an extremely precise control of aqueous/oil flows for perfect...

Microfluidic automation using elastomeric valves and droplets: reducing reliance on external controllers.

Small (Weinheim an der Bergstrasse, Germany)

Kim SJ, Lai D, Park JY, Yokokawa R, Takayama S.
PMID: 22761019
Small. 2012 Oct 08;8(19):2925-34. doi: 10.1002/smll.201200456. Epub 2012 Jul 03.

This paper gives an overview of elastomeric valve- and droplet-based microfluidic systems designed to minimize the need of external pressure to control fluid flow. This Concept article introduces the working principle of representative components in these devices along with...

Measuring the growth rate of cells, one at a time.

Nature methods

Charvin G.
PMID: 20431549
Nat Methods. 2010 May;7(5):363. doi: 10.1038/nmeth0510-363.

No abstract available.

Micropillar sequence designs for fundamental inertial flow transformations.

Lab on a chip

Stoecklein D, Wu CY, Owsley K, Xie Y, Di Carlo D, Ganapathysubramanian B.
PMID: 25268387
Lab Chip. 2014 Nov 07;14(21):4197-204. doi: 10.1039/c4lc00653d.

The ability to control the shape of a flow in a passive microfluidic device enables potential applications in chemical reaction control, particle separation, and complex material fabrication. Recent work has demonstrated the concept of sculpting fluid streams in a...

Integrated capture, transport, and magneto-mechanical resonant sensing of superparamagnetic microbeads using magnetic domain walls.

Lab on a chip

Rapoport E, Montana D, Beach GS.
PMID: 22955796
Lab Chip. 2012 Nov 07;12(21):4433-40. doi: 10.1039/c2lc40715a.

An integrated platform for the capture, transport, and detection of individual superparamagnetic microbeads is described for lab-on-a-chip biomedical applications. Magnetic domain walls in magnetic tracks have previously been shown to be capable of capturing and transporting individual beads through...

Numerical and experimental characterization of a novel modular passive micromixer.

Biomedical microdevices

Pennella F, Rossi M, Ripandelli S, Rasponi M, Mastrangelo F, Deriu MA, Ridolfi L, Kähler CJ, Morbiducci U.
PMID: 22711456
Biomed Microdevices. 2012 Oct;14(5):849-62. doi: 10.1007/s10544-012-9665-4.

This paper reports a new low-cost passive microfluidic mixer design, based on a replication of identical mixing units composed of microchannels with variable curvature (clothoid) geometry. The micromixer presents a compact and modular architecture that can be easily fabricated...

Measuring microchannel electroosmotic mobility and zeta potential by the current monitoring method.

Methods in molecular biology (Clifton, N.J.)

Shao C, Devoe DL.
PMID: 23329435
Methods Mol Biol. 2013;949:55-63. doi: 10.1007/978-1-62703-134-9_4.

Electroosmotic flow (EOF) is an electrokinetic flow control technique widely used in microfluidic systems for applications including direct electrokinetic pumping, hydrodynamic pressure generation, and counterflow for microfluidic separations. During EOF, an electric field is applied along the length of...

Programmed trapping of individual bacteria using micrometre-size sieves.

Lab on a chip

Kim MC, Isenberg BC, Sutin J, Meller A, Wong JY, Klapperich CM.
PMID: 21293825
Lab Chip. 2011 Mar 21;11(6):1089-95. doi: 10.1039/c0lc00362j. Epub 2011 Feb 04.

Monitoring the real-time behavior of spatial arrays of single living bacteria cells is only achieved with much experimental difficulty due to the small size and mobility of the cells. To address this problem, we have designed and constructed a...

Droplet microfluidics--a tool for single-cell analysis.

Angewandte Chemie (International ed. in English)

Joensson HN, Andersson Svahn H.
PMID: 23180509
Angew Chem Int Ed Engl. 2012 Dec 03;51(49):12176-92. doi: 10.1002/anie.201200460. Epub 2012 Nov 23.

Droplet microfluidics allows the isolation of single cells and reagents in monodisperse picoliter liquid capsules and manipulations at a throughput of thousands of droplets per second. These qualities allow many of the challenges in single-cell analysis to be overcome....

Controlled gating and electrical detection of single 50S ribosomal subunits through a solid-state nanopore in a microfluidic chip.

Biosensors & bioelectronics

Rudenko MI, Holmes MR, Ermolenko DN, Lunt EJ, Gerhardt S, Noller HF, Deamer DW, Hawkins A, Schmidt H.
PMID: 21855314
Biosens Bioelectron. 2011 Nov 15;29(1):34-9. doi: 10.1016/j.bios.2011.07.047. Epub 2011 Aug 05.

We describe analysis and control of 50S ribosomal subunits by a solid-state 45nm diameter nanopore incorporated in a microfluidic chip. When used as a resistive pulse sensor, translocation of single 50S subunits through the nanopore produces current blockades that...

Microfluidic fabrication of complex-shaped microfibers by liquid template-aided multiphase microflow.

Lab on a chip

Choi CH, Yi H, Hwang S, Weitz DA, Lee CS.
PMID: 21390381
Lab Chip. 2011 Apr 21;11(8):1477-83. doi: 10.1039/c0lc00711k. Epub 2011 Mar 10.

This study presents a simple microfluidic approach to the rapid fabrication of complex-shaped microfibers (e.g., single hollow, double hollow, and microbelt), with highly uniform structures, based on a combination of the spontaneous formation of polymeric jet streams and in...

Showing 13 to 24 of 203 entries