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Showing 1837 to 1847 of 1847 entries
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The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial-stellate cell deactivation induced by statins.

Marrone G, Russo L, Rosado E, Hide D, García-Cardeña G, García-Pagán JC, Bosch J, Gracia-Sancho J.
PMID: 22989565
J Hepatol. 2013 Jan;58(1):98-103. doi: 10.1016/j.jhep.2012.08.026. Epub 2012 Sep 16.

BACKGROUND & AIMS: Statins improve hepatic endothelial function and liver fibrosis in experimental models of cirrhosis, thus they have been proposed as therapeutic options to ameliorate portal hypertension syndrome. The transcription factor Kruppel-like factor 2 (KLF2) may be induced...

The effects of terlipressin and direct portacaval shunting on liver hemodynamics following 80% hepatectomy in the pig.

Hammond JS, Godtliebsen F, Steigen S, Guha IN, Wyatt J, Revhaug A, Lobo DN, Mortensen KE.
PMID: 30606815
Clin Sci (Lond). 2019 Jan 15;133(1):153-166. doi: 10.1042/CS20180858. Print 2019 Jan 15.

Liver failure is the major cause of death following liver resection. Post-resection portal venous pressure (PVP) predicts liver failure, is implicated in its pathogenesis, and when PVP is reduced, rates of liver dysfunction decrease. The aim of the present...

The impact of microbubble-enhanced therapeutic ultrasound combined with prothrombin on microwave ablation in the rabbit liver.

Shi Y, Liu X, Luo Z, Gu F, He J, Yan P, Zhang J, Zhou X.
PMID: 27981275
Med Ultrason. 2016 Dec 05;18(4):438-445. doi: 10.11152/mu-869.

AIM: This study aimed to investigate the effect of microbubble-enhanced ultrasound (MEUS) combined with prothrombin on regional hepatic circulation and microwave ablation (MWA) in rabbit livers.MATERIALS AND METHODS: High-pressureamplitude therapeutic ultrasound (TUS) was used to treat 52 surgically exposed...

Age-associated loss of immunomodulatory protection by granulocyte-colony stimulating factor in endotoxic rats.

Vollmar B, Pradarutti S, Nickels RM, Menger MD.
PMID: 12392279
Shock. 2002 Oct;18(4):348-54. doi: 10.1097/00024382-200210000-00010.

Elderly patients have a higher incidence of morbidity and mortality due to infectious diseases. Because most immune functions in the elderly differ compared with those in younger subjects, we studied the effect of the immunomodulating agent G-CSF on endotoxic...

Receptor subtype mediating the action of circulating endothelin on glucose metabolism and hemodynamics in perfused rat liver.

Cui TX, Iwai M, Hamai M, Shimazu T.
PMID: 10511465
Regul Pept. 1999 Sep 15;83(2):117-22. doi: 10.1016/s0167-0115(99)00058-0.

The subtype of endothelin receptor that mediates metabolic and hemodynamic effects of circulating endothelin was explored using perfused rat liver. Infusion of endothelin (ET)-1 or ET-3 into the portal vein at a concentration of 0.3 nM increased glucose and...

l-Arginine supplementation protects against hepatic ischemia-reperfusion lesions in rabbits.

Taha MO, Simões MJ, Haddad MA, Capelato RC, Budny N, Matsumoto AH, Soares PC, Santos WM, Armeato GD, Araki CM, Gomes JS, Magalhães KG, Tersariol IL, Monteiro HP, Oliveira-Júnior IS, Oliveira I, Jurkiewicz A, Caricati-Neto A.
PMID: 19376360
Transplant Proc. 2009 Apr;41(3):816-9. doi: 10.1016/j.transproceed.2009.02.050.

We evaluated the effects of a substrate in the biosynthesis of nitric oxide (NO)-l-arginine (LARG)-on hepatic lesions caused by ischemia/reperfusion (I/R) injury in rabbit livers. Rabbits were pretreated with LARG (150 mg/kg IV) or saline solution 0.9% (SS) before...

Preoperative liver hypertrophy induced by portal flow occlusion before major hepatic resection for colorectal metastases can be impaired by bevacizumab.

Aussilhou B, Dokmak S, Faivre S, Paradis V, Vilgrain V, Belghiti J.
PMID: 19363584
Ann Surg Oncol. 2009 Jun;16(6):1553-9. doi: 10.1245/s10434-009-0447-z. Epub 2009 Apr 11.

BACKGROUND: This prospective study evaluated the effect of bevacizumab on the hypertrophy of the future liver remnant (FLR) after portal vein occlusion (PVO) before major hepatectomy for colorectal liver metastases.METHODS: Twenty-seven patients with colorectal liver metastases treated with preoperative...

Dopamine versus norepinephrine: is one better?.

Vincent JL, Biston P, Devriendt J, Brasseur A, De Backer D.
PMID: 19412154
Minerva Anestesiol. 2009 May;75(5):333-7.

Dopamine and norepinephrine are widely used as first line agents to correct hypotension in patients with acute circulatory failure. There has been considerable debate in recent years as to whether one is better than the other. Both drugs can...

Hepatic neovascularization after partial portal vein ligation: novel mechanism of chronic regulation of blood flow.

Yokoyama Y, Baveja R, Sonin N, Clemens MG, Zhang JX.
PMID: 11123194
Am J Physiol Gastrointest Liver Physiol. 2001 Jan;280(1):G21-31. doi: 10.1152/ajpgi.2001.280.1.G21.

The present study was undertaken to investigate hepatic microcirculatory response following partial portal vein ligation (PPVL) in rats. Portal pressure was markedly increased 2-6 wk after PPVL, but no significant reduction in sinusoidal perfusion and hepatocellular injury were detected....

[Effect of vasoactive intestinal polypeptide on liver blood flow in rat].

Nakata S, Morise K, Mitsuma T.
PMID: 2871207
Nihon Shokakibyo Gakkai Zasshi. 1986 Jan;83(1):72-8.

No abstract available.

[Halothane hepatotoxicity and hepatic circulation].

Hori T, Nagasaka H, Matsumoto N.
PMID: 3294458
Masui. 1988 Mar;37(3):268-79.

No abstract available.

Showing 1837 to 1847 of 1847 entries